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Hydrated lipidic lamellar phases or liposomes based on ecdysteroids

Assignee: LVMH Recherche GIE
•
Filing: 1989-10-02
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Granted: 1993-03-30
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Expires: 2009-10-02
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Abstract

Abstract PCT No. PCT/FR89/00507 Sec. 371 Date Mar. 22, 1991 Sec. 102(e) Date Mar. 22, 1991 PCT Filed Oct. 2, 1989 PCT Pub. No. WO90/03778 PCT Pub. Date Apr. 19, 1990.Compositions based on hydrated lipidic lamellar phases or liposomes are disclosed containing at least in part at least one ecdysteroid or ecdysteroid derivative, in particular ecdysterone, or a plant or animal extract containing the said ecdysteroid or ecdysteroid derivative. Cosmetic or pharmaceutical compositions can be prepared as well as compositions for sericulture or a phytosanitary composition.

Inventors

  • 👤 Alain Meybeck
  • 👤 Frederic Bonte

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 12:24
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/02; A61K8/14; A61K31/00; A61K31/56; A61K31/575; A61K8/18; A61K8/30; A61K8/63; A61K9/00; A61K9/10; A61K9/127; A61Q; A61Q19/00; A61Q19/08; Y; Y10; Y10T; Y10T428/00; Y10T428/29; Y10T428/2982; Y10T428/2984

Claims Analysis

Total Claims: 51
Claim 1
Independent Claim 27 words
A composition comprising hydrated lipidic lamellar phases or liposomes containing at least one ecdysteroid in a concentration ranging between 0.0001 and 5% by weight of the composition.
Claim 2
Dependent Claim 27 words
A composition comprising hydrated lipidic lamellar phases or liposomes containing at least one ecdysteroid in a concentration ranging between 0.0001 and 5% by weight of the composition.
Claim 3
Dependent Claim 30 words
The composition of claim 1, wherein the ecdysteroid is selected from the group consisting of ecdysterone, an acylated ecdysterone, an hydroxylated ecdysterone, a deoxyecdysterone, α-ecdysone, 2-deoxyecdysone and a β-ecdysone acetate.
Claim 4
Dependent Claim 24 words
The composition of claim 1, wherein the ecdysteroid is selected from the group consisting of ecdysterone, β-ecdysone-2-acetate, β-ecdysone-3-acetate, β-ecdysone-2,3-diacetate, β-ecdysone-2,3,22-triacetate, β-ecdysone-2,3,22,25-tetraacetate, 5-hydroxyecdysterone, and 2-deoxyecdysterone.
Claim 5
Dependent Claim 10 words
The composition of claim 1, wherein the ecdysteroid is ecdysterone.
Claim 6
Dependent Claim 26 words
The composition of claim 1, wherein the ecdysteroid is extracted from a plant selected from the group consisting of Polypodium vulgare, Ajuga decumbens, and Cyanotis arachnoidea.
Claim 7
Dependent Claim 25 words
The composition of claim 1, wherein the ecdysteroid is at least partially incorporated into the lipidic phase of the hydrated lipidic lamellar phases or liposomes.
Claim 8
Dependent Claim 22 words
The composition of claim 6, wherein the concentration of the ecdysteroid ranges between 0.001 and 30% by weight of said lipidic phase.
Claim 9
Dependent Claim 21 words
The composition of claim 1, wherein the concentration of the ecdysteroid ranges between 0.001 and 5% by weight of the composition.
Claim 10
Dependent Claim 22 words
The composition of claim 6, wherein the concentration of the ecdysteroid ranges between 0.01 and 10% by weight of said lipidic phase.
Claim 11
Dependent Claim 39 words
A cosmetic or pharmaceutical composition comprising hydrated lipidic lamellar phases or liposomes containing at least one ecdysteroid in a concentration ranging between 0.001 and 5% by weight of the composition, in admixture with a cosmetically or pharmaceutically acceptable excipient.
Claim 12
Dependent Claim 39 words
A cosmetic or pharmaceutical composition comprising hydrated lipidic lamellar phases or liposomes containing at least one ecdysteroid in a concentration ranging between 0.001 and 5% by weight of the composition, in admixture with a cosmetically or pharmaceutically acceptable excipient.
Claim 13
Dependent Claim 21 words
The composition of claim 10, wherein the concentration of the ecdysteroid ranges between 0.05 and 1% by weight of the composition.
Claim 14
Dependent Claim 30 words
The composition of claim 10, wherein the ecdysteroid is selected from the group consisting of ecdysterone, an acylated ecdysterone, an hydroxylated ecdysterone, a deoxyecdysterone, β-ecdysone, 2-deoxyecdysone and a β-ecdysone acetate.
Claim 15
Dependent Claim 24 words
The composition of claim 10, wherein the ecdysteroid is selected from the group consisting of ecdysterone, β-ecdysone-2-acetate, β-ecdysone-3-acetate, β-ecdysone-2,3-diacetate, β-ecdysone-2,3,22-triacetate, β-ecdysone-2,3,22,25-tetraacetate, 5-hydroxyecdysterone, and 2-deoxyecdysterone.
Claim 16
Dependent Claim 10 words
The composition of claim 10, wherein the ecdysteroid is ecdysterone.
Claim 17
Dependent Claim 26 words
The composition of claim 10, wherein the ecdysteroid is extracted from a plant selected from the group consisting of Polypodium vulgare, Ajuga decumbens, and Cyanotis arachnoidea.
Claim 18
Dependent Claim 25 words
The composition of claim 10, wherein the ecdysteroid is at least partially incorporated into the lipidic phase of the hydrated lipidic lamellar phases or liposomes.
Claim 19
Dependent Claim 22 words
The composition of claim 16, wherein the concentration of the ecdysteroid ranges between 0.001 and 30% by weight of said lipidic phase.
Claim 20
Dependent Claim 22 words
The composition of claim 16, wherein the concentration of the ecdysteroid ranges between 0.01 and 10% by weight of said lipidic phase.
Claim 21
Dependent Claim 29 words
A composition for sericulture comprising hydrated lipidic lamellar phases or liposomes containing at least one ecdysteroid in a concentration ranging between 0.0001 and 1% by weight of the composition.
Claim 22
Dependent Claim 29 words
A composition for sericulture comprising hydrated lipidic lamellar phases or liposomes containing at least one ecdysteroid in a concentration ranging between 0.0001 and 1% by weight of the composition.
Claim 23
Dependent Claim 21 words
The composition of claim 19, wherein the concentration of the ecdysteroid ranges between 0.0005 and 0.01% by weight of the composition.
Claim 24
Dependent Claim 30 words
The composition of claim 19, wherein the ecdysteroid is selected from the group consisting of ecdysterone, an acylated ecdysterone, an hydroxylated ecdysterone, a deoxyecdysterone, α-ecdysone, 2-deoxyecdysone and a β-ecdysone acetate.
Claim 25
Dependent Claim 24 words
The composition of claim 19, wherein the ecdysteroid is selected from the group consisting of ecdysterone, β-ecdysone-2-acetate, β-ecdysone-3-acetate, β-ecdysone-2,3-diacetate, β-ecdysone-2,3,22-triacetate, β-ecdysone-2,3,22,25-tetraacetate, 5-hydroxyecdysterone, and 2-deoxyecdysterone.
Claim 26
Dependent Claim 10 words
The composition of claim 19, wherein the ecdysteroid is ecdysterone.
Claim 27
Dependent Claim 26 words
The composition of claim 19, wherein the ecdysteroid is extracted from a plant selected from the group consisting of Polypodium vulgare, Ajuga decumbens, and Cyanotis arachnoidea.
Claim 28
Dependent Claim 25 words
The composition of claim 19, wherein the ecdysteroid is at least partially incorporated into the lipidic phase of the hydrated lipidic lamellar phases or liposomes.
Claim 29
Dependent Claim 22 words
The composition of claim 25, wherein the concentration of the ecdysteroid ranges between 0.001 and 30% by weight of said lipidic phase.
Claim 30
Dependent Claim 22 words
The composition of claim 25, wherein the concentration of the ecdysteroid ranges between 0.01 and 10% by weight of said lipidic phase.
Claim 31
Dependent Claim 28 words
A phytosanitary composition comprising hydrated lipidic lamellar phases or liposomes containing at least one ecdysteroid in a concentration ranging between 0.0001 and 5% by weight of the composition.
Claim 32
Dependent Claim 28 words
A phytosanitary composition comprising hydrated lipidic lamellar phases or liposomes containing at least one ecdysteroid in a concentration ranging between 0.0001 and 5% by weight of the composition.
Claim 33
Dependent Claim 21 words
The composition of claim 28, wherein the concentration of the ecdysteroid ranges between 0.0005 and 1% by weight of the composition.
Claim 34
Dependent Claim 30 words
The composition of claim 28, wherein the ecdysteroid is selected from the group consisting of ecdysterone, an acylated ecdysterone, an hydroxylated ecdysterone, a deoxyecdysterone, α-ecdysone, 2-deoxyecdysone and a β-ecdysone acetate.
Claim 35
Dependent Claim 24 words
The composition of claim 28, wherein the ecdysteroid is selected from the group consisting of ecdysterone, β-ecdysone-2-acetate, β-ecdysone-3-acetate, β-ecdysone-2,3-diacetate, β-ecdysone-2,3,22-triacetate, β-ecdysone-2,3,22,25-tetraacetate, 5-hydroxyecdysterone, and 2-deoxyecdysterone.
Claim 36
Dependent Claim 10 words
The composition of claim 28, wherein the ecdysteroid is ecdysterone.
Claim 37
Dependent Claim 26 words
The composition of claim 28, wherein the ecdysteroid is extracted from a plant selected from the group consisting of Polypodium vulgare, Ajuga decumbens, and Cyanotis arachnoidea.
Claim 38
Dependent Claim 25 words
The composition of claim 28, wherein the ecdysteroid is at least partially incorporated into the lipidic phase of the hydrated lipidic lamellar phases or liposomes.
Claim 39
Dependent Claim 22 words
The composition of claim 34, wherein the concentration of the ecdysteroid ranges between 0.001 and 30% by weight of said lipidic phase.
Claim 40
Dependent Claim 22 words
The composition of claim 34, wherein the concentration of the ecdysteroid ranges between 0.01 and 10% by weight of said lipidic phase.
Claim 41
Independent Claim 54 words
A method for regenerating the cutaneous structure, comprising applying to the area of the skin to be treated, in an amount sufficient to regenerate the cutaneous structure, a composition comprising hydrated lipidic lamellar phases or liposomes containing at least one ecdysteroid in a concentration ranging between 0.001 and 5% by weight of the composition.
Claim 42
Independent Claim 54 words
A method for regenerating the cutaneous structure, comprising applying to the area of the skin to be treated, in an amount sufficient to regenerate the cutaneous structure, a composition comprising hydrated lipidic lamellar phases or liposomes containing at least one ecdysteroid in a concentration ranging between 0.001 and 5% by weight of the composition.
Claim 43
Dependent Claim 13 words
The method of claim 37, for producing an anti-wrinkling effect on the skin.
Claim 44
Dependent Claim 13 words
The method of claim 37, for producing a cicatrizing effect on the skin.
Claim 45
Dependent Claim 13 words
The method of claim 37, for producing an anti-aging effect on the skin.
Claim 46
Dependent Claim 13 words
The method of claim 37, for producing a tonic effect on the hair.
Claim 47
Dependent Claim 30 words
The method of claim 37, wherein the ecdysteroid is selected from the group consisting of ecdysterone, an acylated ecdysterone, an hydroxylated ecdysterone, a deoxyecdysterone, α-ecdysone, 2-deoxyecdysone and a β-ecdysone acetate.
Claim 48
Dependent Claim 24 words
The method of claim 37, wherein the ecdysteroid is selected from the group consisting of ecdysterone, β-ecdysone-2-acetate, β-ecydysone-3acetate, β-ecdysone-2,3-diacetate, β-ecdysone-2,3,22-triacetate, β-ecdysone-2,3,22,25-tetraacetate, 5-hydroxyecdysterone, and 2-deoxyecdysterone.
Claim 49
Dependent Claim 25 words
The method of claim 37, wherein the ecdysteroid is at least partially incorporated into the lipidic phase of the hydrated lipidic lamellar phases or liposomes.
Claim 50
Dependent Claim 26 words
The method of claim 44, wherein the concentration of the ecdysteroid in the lipidic phase ranges between 0.001 and 30% by weight of said lipidic phase.
Claim 51
Dependent Claim 26 words
The method of claim 44, wherein the concentration of the ecdysteroid in the lipidic phase ranges between 0.01 and 10% by weight of said lipidic phase.

References Cited (Backward Citations)

US4427649A Cited
US4508703A Cited
US4485054A Cited
US4891219A Cited

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