US5128147A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Heat intensifier and localizer for radiofrequency thermotherapy
Assignee: Thermal Developments Inc
•
Filing: 1990-08-06
•
Granted: 1992-07-07
•
Expires: 2010-08-06
Abstract
Abstract A sterile injectable mixture which intensifies and localizes radio frequency thermotherapy; the injectable mixture contains finely ground ferrite particles in a viscid aqueous suspension, the ferrite being matched for maximum radio frequency absorption at a specific frequency. A chemotherapeutic agent, a surfactant and a bioacceptable hydrophic colloid are also contained in the mixture.
Inventors
- 👤 Harry H. Leveen
- 👤 Eric G. LeVeen
- 👤 Robert F. Leveen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 07:34
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0002; A61K9/0009
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
68 words
A sterile injectable mixture for injection into a tumor which intensifies and localizes radio frequency thermotherapy of the tumor, said mixture comprising the combination of finely ground manganese zinc ferrite means in an aqueous suspension, a surfactant, a chemotheraputic agent, an anesthetic agent and a thickening agent, said manganese zinc ferrite means comprising individual manganese and zinc complexed ferrite particles coated by microencapsulation with an inert plastic para-di-zylene.
Claim 2
Dependent Claim
68 words
A sterile injectable mixture for injection into a tumor which intensifies and localizes radio frequency thermotherapy of the tumor, said mixture comprising the combination of finely ground manganese zinc ferrite means in an aqueous suspension, a surfactant, a chemotheraputic agent, an anesthetic agent and a thickening agent, said manganese zinc ferrite means comprising individual manganese and zinc complexed ferrite particles coated by microencapsulation with an inert plastic para-di-zylene.
Claim 3
Dependent Claim
18 words
A sterile injectable mixture as claimed in claim 1 wherein said aqueous suspension is in a saline solution.
Claim 4
Dependent Claim
18 words
A sterile injectable mixture as claimed in claim 1 wherein said aqueous suspension is a bioacceptable hydrophillic colloid.
Claim 5
Dependent Claim
16 words
A sterile injectable mixture as claimed in claim 3 wherein said hydrophillic colloid is sodium alginate.
Claim 6
Dependent Claim
15 words
A sterile injectable mixture as claimed in claim 3 wherein said hydrophillic colloid is dextran.
Claim 7
Dependent Claim
15 words
A sterile injectable mixture as claimed in claim 3 wherein said hydrophillic colloid is carbowax.
Claim 8
Dependent Claim
14 words
A sterile injectable mixture as claimed in claim 1 wherein said surfactant is lecithin.
Claim 9
Dependent Claim
17 words
A sterile injectable mixture as claimed in claim 1 wherein said surfactant is a non ionic detergent.
Claim 10
Dependent Claim
15 words
A sterile injectable mixture as claimed in claim 1 wherein said surfactant is a hydroxycellulose.
Claim 11
Dependent Claim
15 words
A sterile injectable mixture as claimed in claim 1 wherein said anesthetic agent is lidocaine.
Claim 12
Dependent Claim
15 words
A sterile injectable mixture as claimed in claim 1 wherein said anesthetic agent is porcaine.
Claim 13
Dependent Claim
99 words
A sterile injectable mixture for injection into a tumor which intensifies and localizes radio frequency thermotherapy, said mixture containing finely ground complexed manganese zinc ferrite particles in powder form, said complexed manganese zinc ferrite particles being at least two thirds iron and encapsulated in biologically inert plastic material in a viscid aqueous suspension, said complexed manganeses zinc ferrite particles being matched for maximum radio frequency absorption ranging from 13.56 mHz to about 27.12 mHz and substantially totally absorbing the energy of the radio frequency waves, said mixture further containing a chemotherapeutic agent, a surfactant and a bioacceptable hydrophillic colloid.
Claim 14
Dependent Claim
99 words
A sterile injectable mixture for injection into a tumor which intensifies and localizes radio frequency thermotherapy, said mixture containing finely ground complexed manganese zinc ferrite particles in powder form, said complexed manganese zinc ferrite particles being at least two thirds iron and encapsulated in biologically inert plastic material in a viscid aqueous suspension, said complexed manganeses zinc ferrite particles being matched for maximum radio frequency absorption ranging from 13.56 mHz to about 27.12 mHz and substantially totally absorbing the energy of the radio frequency waves, said mixture further containing a chemotherapeutic agent, a surfactant and a bioacceptable hydrophillic colloid.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-07-07 | 1996-01-06 | 1996-07-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-07-07 | 2000-01-06 | 2000-07-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-07-07 | 2004-01-06 | 2004-07-07 | $7700.00 | Window Closed / Lapsed |