US5092838A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Histidine buffered peritoneal dialysis solution
Assignee: Baxter International Inc
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Filing: 1989-11-30
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Granted: 1992-03-03
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Expires: 2009-11-30
Abstract
Abstract A peritoneal dialysis solution buffered with L-histidine to a pH of at least 6.5. An apparatus and method for utilizing the solution is also disclosed.
Inventors
- 👤 Dirk Faict
- 👤 Francesco Peluso
- 👤 Patrick Balteau
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 02:46
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/14; A61M1/16; A61M1/28; A61M1/287; A61P; A61P7/00; A61P7/08
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
136 words
A method of performing peritoneal dialysis comprising: providing a first container of solution having a pH of less than 6; providing a second container of solution including an amino acid buffer being chosen from the group consisting essentially of histidine, its isomers, polymers and derivatives in a concentration such that after mixing said solutions, the final pH of the mixed solution will be greater than 6.5; providing fluid connection means connecting said first and second containers, said connection means being initially sealed to keep said solutions initially separate, said connections means being unsealable to allow mixing of said solutions; providing means for delivering the mixture of said solutions to a patient to perform peritoneal dialysis; unsealing said connections means to open said fluid connection; mixing said solutions; and delivering said mixed solution via said delivery means.
Claim 2
Independent Claim
136 words
A method of performing peritoneal dialysis comprising: providing a first container of solution having a pH of less than 6; providing a second container of solution including an amino acid buffer being chosen from the group consisting essentially of histidine, its isomers, polymers and derivatives in a concentration such that after mixing said solutions, the final pH of the mixed solution will be greater than 6.5; providing fluid connection means connecting said first and second containers, said connection means being initially sealed to keep said solutions initially separate, said connections means being unsealable to allow mixing of said solutions; providing means for delivering the mixture of said solutions to a patient to perform peritoneal dialysis; unsealing said connections means to open said fluid connection; mixing said solutions; and delivering said mixed solution via said delivery means.
Claim 3
Dependent Claim
25 words
The method of claim 1 wherein the amino acid concentration of said mixed solution is in the range of 0.01 to 60 millimoles per liter.
Claim 4
Dependent Claim
25 words
The method of claim 2 wherein the amino acid concentration of said mixed solution is in the range of 1 to 20 millimoles per liter.
Claim 5
Dependent Claim
12 words
The method of claim 1 wherein said amino acid buffer is L-histidine.
Claim 6
Dependent Claim
35 words
A peritoneal dialysis solution buffered with at least one amino acid to a pH of at least 6.5, said amino acid being chosen from the group consisting essentially of histidine, its isomers, polymers and derivatives.
Claim 7
Dependent Claim
35 words
A peritoneal dialysis solution buffered with at least one amino acid to a pH of at least 6.5, said amino acid being chosen from the group consisting essentially of histidine, its isomers, polymers and derivatives.
Claim 8
Dependent Claim
13 words
The peritoneal dialysis solution of claim 5 wherein said amino acid is L-histidine.
Claim 9
Dependent Claim
20 words
The peritoneal dialysis solution of claim 6 wherein said solution comprises 0.01 to 60 millimoles per liter of said L-histidine.
Claim 10
Dependent Claim
21 words
The peritoneal dialysis solution of claim 7 wherein said solution comprises between 1 to 20 millimoles per liter of said L-histidine.
Claim 11
Dependent Claim
21 words
The peritoneal dialysis solution of claim 5 wherein said solution comprises 0.01 to 60 millimoles per liter of said amino acid.
Claim 12
Dependent Claim
22 words
The peritoneal dialysis solution of claim 9 wherein said solution comprises between 1 to 20 millimoles per liter of said amino acid.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-03-03 | 1995-09-02 | 1996-03-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-03-03 | 1999-09-02 | 2000-03-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-03-03 | 2003-09-02 | 2004-03-03 | $7700.00 | Window Closed / Lapsed |