US5032666A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Amine rich fluorinated polyurethaneureas and their use in a method to immobilize an antithrombogenic agent on a device surface
Assignee: Becton Dickinson and Co
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Filing: 1989-06-19
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Granted: 1991-07-16
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Expires: 2009-06-19
Abstract
Abstract A thermoplastic polyurethaneurea having free amino groups is the reaction product of a diisocyanate, a fluorinated polyol, a non-fluorinated polyol and a polyamine. The invention includes a shaped polymeric support structure having the thermoplastic polyurethaneurea coated thereon and a medical article comprising the coated support and heparin covalently bonded to the free amino groups of the coated support. In another aspect of the invention, a method for preparing the heparinized medical article is provided.
Inventors
- 👤 Can B. Hu
- 👤 Donald D. Solomon
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 01:29
CPC Classifications
C; C08; C08G; C08G18/00; C08G18/06; C08G18/28; C08G18/40; C08G18/48; C08G18/50; C08G18/5003; C08G18/5015; A; A61; A61L; A61L33/00; A61L33/0005; A61L33/0011; A61L33/0029; C08G18/08; C08G18/10; C08G18/12
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
47 words
A thermoplastic polyurethaneurea having reactive amino groups comprising a product from the reaction of a diisocyanate, a polyamine and a mixture of polyols comprising a fluorinated polyol and a nonfluorinated polyol, said nonfluorinated polyol being selected from the group consisting of a polyalkyleneoxide polyol and a polyesterpolyol.
Claim 2
Dependent Claim
47 words
A thermoplastic polyurethaneurea having reactive amino groups comprising a product from the reaction of a diisocyanate, a polyamine and a mixture of polyols comprising a fluorinated polyol and a nonfluorinated polyol, said nonfluorinated polyol being selected from the group consisting of a polyalkyleneoxide polyol and a polyesterpolyol.
Claim 3
Dependent Claim
25 words
The polyurethaneurea of claim 1 wherein said diisocyanate is selected from the group consisting of 4,4'-diphenylmethane-diisocyanate, 3,3'-diphenylmethane-diisocyanate, 4,4'-dicyclohexylmethane-diisocyanate, isophorone diisocyanate, hexamethylene diisocyanate and mixtures thereof.
Claim 4
Dependent Claim
51 words
The polyurethaneurea of claim 1 wherein said fluorinated polyol is selected from the group having the formula ##STR2## wherein R is a perfluorinated alkyl group having about 1 to 12 carbon atoms, x is about 1 to 4, y is about 0 to 20 and z is about 2 to 5.
Claim 5
Dependent Claim
26 words
The polyurethaneurea of claim 1 wherein said polyalkyleneoxide polyol is selected from the group consisting of polytetramethylene ether glycol, polypropylene glycol, polyethylene glycol and mixtures thereof.
Claim 6
Dependent Claim
28 words
The polyurethaneurea of claim 1 wherein said polyamine is selected from the group consisting of a diamine having from 2 to 20 carbon atoms and a polyoxyethylene diamine.
Claim 7
Dependent Claim
31 words
A thermoplastic polyurethaneurea having reactive amino groups comprising a product from the reaction of 4,4'-diphenylmethane-diisocyanate, a polyamine and a mixture of polyols consisting of a fluorinated polyether polyol and polytetramethylenether glycol.
Claim 8
Dependent Claim
31 words
A thermoplastic polyurethaneurea having reactive amino groups comprising a product from the reaction of 4,4'-diphenylmethane-diisocyanate, a polyamine and a mixture of polyols consisting of a fluorinated polyether polyol and polytetramethylenether glycol.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-07-15 | 1995-01-14 | 1995-07-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-07-15 | 1999-01-14 | 1999-07-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-07-15 | 2003-01-14 | 2003-07-16 | $7700.00 | Window Closed / Lapsed |