US4994030A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Reconstitution of human bone and tissue
Assignee: Osteotech Investment Corp
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Filing: 1988-06-28
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Granted: 1991-02-19
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Expires: 2008-06-28
Abstract
Abstract A kit and process for reconstituting human bone and/or related tissue is disclosed. The kit comprises a pre-formulated sterilized reconstitution medium and double ended transfer needle.
Inventors
- 👤 Frank P. Glowczewskie, Jr.
- 👤 David A. Present
- 👤 David W. Anderson
- 👤 Patrick A. McBrayer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 01:58
CPC Classifications
A; A61; A61J; A61J1/00; A61J1/14; A61J1/20; A61J1/2089; A61F; A61F2/00; A61F2/02; A61F2/28; A61B; A61B50/00; A61B2050/005; A61B2050/0051; A61B2050/0056; A61B50/30; A61B50/31; A61B2050/311; A61J1/2003; A61J1/2006; A61J1/201; A61J1/2013
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
166 words
A kit for reconstituting human tissue selected from the group consisting of bone and musculoskeletal tissue, said kit comprising: (a) a sealed vessel containing a sterile preformulated reconstitution medium for said human tissue, said sealed vessel comprising an access site into the interior of said vessel; and (b) means for accessing the interior of said sealed vessel and for placing the interior of said vessel in open communication with the interior of a sealed vessel containing said human tissue necessitating reconstitution; wherein said pre-formulated reconstitution medium comprises a sterile aqueous solution including, in an amount suitable to preserve sterility of said human tissue during reconstitution and subsequent implant, a preservative selected from the group consisting of gentamicin sulfate, bacitracin, polymyxin B, neomycin and cefazolin sodium; and said means of accessing the interior of said sealed vessel comprises a hollow needle having two opposite pointed open ends and being separate from both said sealed vessel containing said reconstitution medium and said sealed vessel containing said human tissue.
Claim 2
Dependent Claim
166 words
A kit for reconstituting human tissue selected from the group consisting of bone and musculoskeletal tissue, said kit comprising: (a) a sealed vessel containing a sterile preformulated reconstitution medium for said human tissue, said sealed vessel comprising an access site into the interior of said vessel; and (b) means for accessing the interior of said sealed vessel and for placing the interior of said vessel in open communication with the interior of a sealed vessel containing said human tissue necessitating reconstitution; wherein said pre-formulated reconstitution medium comprises a sterile aqueous solution including, in an amount suitable to preserve sterility of said human tissue during reconstitution and subsequent implant, a preservative selected from the group consisting of gentamicin sulfate, bacitracin, polymyxin B, neomycin and cefazolin sodium; and said means of accessing the interior of said sealed vessel comprises a hollow needle having two opposite pointed open ends and being separate from both said sealed vessel containing said reconstitution medium and said sealed vessel containing said human tissue.
Claim 3
Dependent Claim
43 words
The kit according to claim 1 wherein said sealed vessel containing said sterile pre-formulated reconstitution medium comprises a vial having a mouth aseptically sealed with a snugly fitting stopper means, said stopper means providing said access site into the interior of said vessel.
Claim 4
Dependent Claim
16 words
The kit according to claim 2 wherein said snugly fitting stopper means is a rubber stopper.
Claim 5
Dependent Claim
145 words
A kit for reconstituting human tissue selected from the group consisting of bone and musculoskeletal tissue, said kit comprising: (a) a sealed vessel containing a sterile preformulated reconstitution medium for said human tissue, said sealed vessel comprising an access site into the interior of said vessel; (b) means for accessing the interior of said sealed vessel and for placing the interior of said vessel in open communication with the interior of a sealed vessel containing said human tissue necessitating reconstitution; wherein said pre-formulated reconstitution medium comprises a sterile aqueous solution of gentamicin sulfate having a concentration of from about 250 to about 1000 micrograms/ml.; and said means of accessing the interior of said sealed vessel comprises a hollow needle having two opposite pointed open ends and being separate from both said sealed vessel containing said reconstitution medium and said sealed vessel containing said human tissue.
Claim 6
Dependent Claim
145 words
A kit for reconstituting human tissue selected from the group consisting of bone and musculoskeletal tissue, said kit comprising: (a) a sealed vessel containing a sterile preformulated reconstitution medium for said human tissue, said sealed vessel comprising an access site into the interior of said vessel; (b) means for accessing the interior of said sealed vessel and for placing the interior of said vessel in open communication with the interior of a sealed vessel containing said human tissue necessitating reconstitution; wherein said pre-formulated reconstitution medium comprises a sterile aqueous solution of gentamicin sulfate having a concentration of from about 250 to about 1000 micrograms/ml.; and said means of accessing the interior of said sealed vessel comprises a hollow needle having two opposite pointed open ends and being separate from both said sealed vessel containing said reconstitution medium and said sealed vessel containing said human tissue.
Claim 7
Dependent Claim
21 words
The kit according to claim 4 wherein said sterile aqueous solution of gentamicin sulfate has a concentration of about 500 micrograms/ml.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-02-18 | 1994-08-20 | 1995-02-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-02-18 | 1998-08-20 | 1999-02-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-02-18 | 2002-08-20 | 2003-02-19 | $7700.00 | Window Closed / Lapsed |