US4986832A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Artificial blood vessel and process for preparing it
Assignee: Ube Corp
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Filing: 1988-08-25
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Granted: 1991-01-22
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Expires: 2008-08-25
Abstract
Abstract Disclosed is an artificial blood comprising a vessel wall that is comprised of plural layers and is porous as a whole, wherein an innermost layer has open-cell structure in which pores are connected through each other, and has a thickness of not less than 5 μm or more and not more than 2/3 of the thickness of the vessel wall. Also disclosed is a process for preparing an artificial blood vessel, comprising the steps of; solidifying a layer that has been formed on the surface of a rod-like substrate by coating a solution comprising a polymeric compound, followed by desolvation to make a rod; coating a solution having the same composition as the solution comprising a polymeric compound, on the inner surface of the rod, and spraying a powder which is insoluble to the polymeric compound solution thereon; solidifying the polymeric compound solution coated on the inner surface of the rod, followed by desolvation; and removing the powder from the polymeric compound.
Inventors
- 👤 Noriaki Kaneko
- 👤 Yoshimi Hirata
- 👤 Masahiro Moriwaki
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 01:49
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/14; A61L27/20; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61L27/16; A61L27/18; A61L27/50; A61L27/56
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
109 words
An artificial blood vessel comprising a vessel wall that is comprised of two layers which have interfaces therebetween and wherein a porous innermost first layer has an open-cell structure in which the cells communicate with each other through interconnecting pores and has a thickness of at least 5 μm and not more than 2/3 of the total wall thickness of the vessel wall; and a second layer which is contiguous to said innermost layer, and has a closed cell structure which prevents blood from permeating therethrough, said closed cell structure comprising closed cells which do not communicate with each other or with the open cells of the innermost layer.
Claim 2
Dependent Claim
109 words
An artificial blood vessel comprising a vessel wall that is comprised of two layers which have interfaces therebetween and wherein a porous innermost first layer has an open-cell structure in which the cells communicate with each other through interconnecting pores and has a thickness of at least 5 μm and not more than 2/3 of the total wall thickness of the vessel wall; and a second layer which is contiguous to said innermost layer, and has a closed cell structure which prevents blood from permeating therethrough, said closed cell structure comprising closed cells which do not communicate with each other or with the open cells of the innermost layer.
Claim 3
Dependent Claim
67 words
The artificial blood vessel according to claim 1, wherein said open-cell structure of the innermost layer is constituted of cells having an average diameter of from 5 to 150 μm and being substantially elongated ovals opening toward an inner surface of the vessel wall and said interconnecting pores having a diameter of at least 3 μm and connecting through each of these cells adjacent to each other.
Claim 4
Dependent Claim
38 words
The artificial blood vessel according to claim 1, wherein said second layer has a thickness of from 5 to 500 μm and is constituted of mutually independent closed pores having a diameter ranging from 0.01 to 100 μm.
Claim 5
Dependent Claim
38 words
The artificial blood vessel according to claim 2, wherein said second layer has a thickness of from 5 to 500 μm and is constituted of mutually independent closed pores having a diameter ranging from 0.01 to 100 μm.
Claim 6
Dependent Claim
35 words
The artificial blood vessel according to claim 1, wherein said vessel wall comprises a polyurethane and at least the innermost layer is reinforced with short fibers made of a synthetic resin distributed at random therein.
Claim 7
Dependent Claim
35 words
The artificial blood vessel according to claim 1, wherein said vessel wall comprises a polyurethaneurea and at least the innermost layer is reinforced with short fibers made of a synthetic resin distributed at random therein.
Claim 8
Dependent Claim
49 words
The artificial blood vessel according to claim 1, further comprising a third layer which is an outermost layer having a group of large pores of from 200 to 300 mm in average diameter to impart flexibility to the vessel wall, restrain kinking and contribute a joining to connective tissues.
Claim 9
Dependent Claim
80 words
The artificial blood vessel according to claim 7, wherein said open-cell structure of the innermost layer is constituted of pores having an average diameter of from 5 to 150 μm and being substantially elongated ovals and/or modified shapes thereof and opening toward an inner surface of the wall vessel with an average diameter of 5 to 150 μm, and interconnecting pores having a diameter of at least 3 μm and connecting through each of these pores adjacent to each other.
Claim 10
Dependent Claim
35 words
The artificial blood vessel according to claim 7, wherein said vessel wall comprises a polyurethane and at least the innermost layer is reinforced with short fibers made of a synthetic resin distributed at random therein.
Claim 11
Dependent Claim
35 words
The artificial blood vessel according to claim 7, wherein said vessel wall comprises a polyurethaneurea and at least the innermost layer is reinforced with short fibers made of a synthetic resin distributed at random therein.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-01-21 | 1994-07-23 | 1995-01-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-01-21 | 1998-07-23 | 1999-01-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-01-21 | 2002-07-23 | 2003-01-22 | $7700.00 | Window Closed / Lapsed |