US4973755A
Expired / Lapsed
US
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Stable solvent adducts of Z-1-(p-β-dimethylaminoethoxy-phenyl)-1-(p-hydroxyphenyl)-2-phenyl-but-1-ene
Assignee: Heumann Pharma GmbH and Co
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Filing: 1988-04-19
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Granted: 1990-11-27
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Expires: 2008-04-19
Abstract
Abstract This invention relates to new stereochemically pure and stable adducts of Z-1-(p-β-dimethylaminoethoxyphenyl)-1-(p-hydroxyphenyl)-2-phenyl-but-1-ene and certain solvents which by virtue of their marked antioestrogenic activities may be used for the therapeutic treatment of benign breast diseases and hormone-dependent mammary tumors, in particularly by percutaneous application.
Inventors
- 👤 Ingomar Grafe
- 👤 Helmut Schickaneder
- 👤 Peter W. Jungblut
- 👤 Kurt H. Ahrens
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 03:44
CPC Classifications
C; C07; C07C; C07C217/00; C07C217/02; C07C217/04; C07C217/06; C07C217/14; C07C217/18; A; A61; A61K; A61K31/00; A61K31/13; A61K31/135; A61P; A61P35/00
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
11 words
A stable solvent adduct of Z-1-(p-β-dimethylaminoethoxyphenyl)-1-(p-hydroxyphenyl)-2-phenyl-but-1-ene corresponding to the formula: ##STR17##
Claim 2
Dependent Claim
11 words
A stable solvent adduct of Z-1-(p-β-dimethylaminoethoxyphenyl)-1-(p-hydroxyphenyl)-2-phenyl-but-1-ene corresponding to the formula: ##STR17##
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US4198435A
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-11-26 | 1994-05-28 | 1994-11-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-11-26 | 1998-05-28 | 1998-11-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-11-26 | 2002-05-28 | 2002-11-27 | $7700.00 | Window Closed / Lapsed |