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US4937369A Expired / Lapsed US ⏱️ 0.0 years remaining

Analogues of phosphatidylcholine or phosphatidyl ethanol amines

Assignee: Abbott Vascular Devices Ltd
•
Filing: 1989-03-27
•
Granted: 1990-06-26
•
Expires: 2009-03-27
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Abstract

Abstract A compound of formulain which X<sup>1</sup> is a reactive group that can react to form a covalent bond with a reactive group on the surface of a material to be rendered biocompatible, X<sup>2</sup> is a group -O<sup>e</sup> or a precursor of such a group, n is 2, 3 or 4, Y is a group -*NR<sub>3</sub>A<sup>e</sup> wherein each R, which may be the same or different, is a C<sub>1</sub>-C<sub>4</sub> alkyl group and A<sup>e</sup> is an anion present when X<sup>2</sup> is an electrically neutral group or Y iswherein R<sup>1</sup> together with X<sup>2</sup> forms a direct bond between the nitrogen and the phosphorus atoms.

Inventors

  • 👤 Dennis Chapman
  • 👤 Aziz A. Durrani

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 11:45
CPC Classifications
C; C07; C07F; C07F9/00; C07F9/02; C07F9/547; C07F9/6564; C07F9/6581; C07F9/6584; C07F9/65842; C07F9/65844; A; A61; A61L; A61L33/00; A61L33/0076; A61L33/0082; C07C; C07C43/00; C07C43/30; C07C43/315; C07F5/00; C07F5/003; C07F9/06; C07F9/08; C07F9/09; C07F9/091

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 70 words
A compound of formula ##STR25## in which X 1 is halogen, X 2 is group --O.sup.⊖ or a precursor of such a group, n is 2, 3 or 4, Y is a group --N + R 3 A - wherein each R which may be the same or different, is a C 1 -C 4 alkyl group and A - is present when X 2 is an electrically neutral group.
Claim 2
Dependent Claim 70 words
A compound of formula ##STR25## in which X 1 is halogen, X 2 is group --O.sup.⊖ or a precursor of such a group, n is 2, 3 or 4, Y is a group --N + R 3 A - wherein each R which may be the same or different, is a C 1 -C 4 alkyl group and A - is present when X 2 is an electrically neutral group.
Claim 3
Dependent Claim 11 words
A compound according to claim 1 wherein X 1 is chlorine.
Claim 4
Dependent Claim 18 words
A compound according to claim 1 wherein Y is --N.sup.⊕ R 3 A.sup.⊖ and each R is methyl.
Claim 5
Dependent Claim 10 words
A compound according to claim 3 wherein n is 2.
Claim 6
Dependent Claim 3 words
Choline acetate dichlorophosphate.
Claim 7
Dependent Claim 3 words
Choline acetate dichlorophosphate.

References Cited (Backward Citations)

US3197431A Cited
US3202633A Cited
US3492193A Cited
US4006176A Cited
US4206156A Cited
US4239709A Cited
US4609646A Cited
US4471131A Cited
US4640790A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1993-06-25 1993-12-25 1994-06-26 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1997-06-25 1997-12-25 1998-06-26 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2001-06-25 2001-12-25 2002-06-26 $7700.00 Window Closed / Lapsed

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