US4934369A
Expired / Lapsed
US
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Intravascular blood parameter measurement system
Assignee: Terumo Cardiovascular Systems Corp
•
Filing: 1989-03-23
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Granted: 1990-06-19
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Expires: 2009-03-23
Abstract
Abstract A parameter of blood is sensed in vivo with a system which includes a catheter and a probe. The catheter has a lumen extending therethrough, a proximal end, a distal end and a distal opening at the distal end. The probe includes one or more sensors at its distal end. A saline solution is introduced into the lumen so that there is an interface adjacent the distal opening of the catheter between the blood and saline solution. The probe is recieved within the catheter and affixed thereto. The interface is moved back and forth in the lumen to expose the sensors to blood so that they can sense the blood parameters of interest.
Inventors
- 👤 Thomas P. Maxwell
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 15:10
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/68; A61B5/6846; A61B5/6847; A61B5/6852; A61B5/145; A61B5/1455; A61B5/1459
Claims Analysis
Total Claims: 32
Claim 1
Independent Claim
133 words
A method of sensing a parameter of blood in vivo comprising: providing a catheter and a sensor in a vessel of a patient with the catheter having a lumen extending therethrough, a proximal end, a distal end and an opening and with the sensor being within the lumen and capable of sensing a parameter in blood and providing a signal in response thereto; introducing an anti-clotting solution into the lumen from a solution-introducing system so that there is an interface between the blood and the solution; moving the interface back and forth in the lumen so that the sensor is exposed to blood for at least a portion of the time that the interface is moving; and oscillator and causing the volume oscillator to expand and contract the volume of the introducing system.
Claim 2
Independent Claim
133 words
A method of sensing a parameter of blood in vivo comprising: providing a catheter and a sensor in a vessel of a patient with the catheter having a lumen extending therethrough, a proximal end, a distal end and an opening and with the sensor being within the lumen and capable of sensing a parameter in blood and providing a signal in response thereto; introducing an anti-clotting solution into the lumen from a solution-introducing system so that there is an interface between the blood and the solution; moving the interface back and forth in the lumen so that the sensor is exposed to blood for at least a portion of the time that the interface is moving; and oscillator and causing the volume oscillator to expand and contract the volume of the introducing system.
Claim 3
Dependent Claim
32 words
A method as defined in claim 1 wherein said step of moving includes expanding and contracting the volume of the solution-introducing system to at least assist in said moving of the interface.
Claim 4
Dependent Claim
33 words
A method as defined in claim 2 wherein said step of moving further includes providing a volume oscillator and causing the volume oscillator to expand and contract the volume of the solution-introducing system.
Claim 5
Dependent Claim
34 words
A method as defined in claim 1 wherein said step of moving includes providing the solution-introducing system with sufficient compliance so that the patient's heartbeats at least assist in said moving of the interface.
Claim 6
Dependent Claim
21 words
A method as defined in claim 1 wherein said step of moving moves the interface back and forth over the sensor.
Claim 7
Dependent Claim
34 words
A method as defined in claim 1 wherein the opening is a distal opening adjacent the distal end and said step of positioning includes positioning the sensor within a distal region of the lumen.
Claim 8
Dependent Claim
32 words
A method as defined in claim 6 wherein the distal opening opens at the distal end and said distal region extends no farther distally than about 0.005 inch proximally of said opening.
Claim 9
Dependent Claim
32 words
A method as defined in claim 6 wherein the distal opening opens at the distal end and said distal region extends no farther proximally than about 0.125 inch proximally of said opening.
Claim 10
Dependent Claim
30 words
A method as defined in claim 1 wherein said step of introducing includes introducing the anti-clotting solution to the lumen to produce a net flow of solution into the patient.
Claim 11
Dependent Claim
71 words
A method as defined in claim 1 wherein said step of positioning includes providing a probe which includes said sensor and transmission means for transmitting the signal from the sensor proximally with the sensor being carried by a distal portion of the transmission means, inserting the probe into said lumen of the catheter and attaching the probe to a proximal location on the catheter to position the sensor in the lumen.
Claim 12
Dependent Claim
20 words
A method as defined in claim 1 wherein said step of obtaining is carried out during said step of moving.
Claim 13
Independent Claim
122 words
A method of sensing a parameter of blood in vivo comprising: providing a catheter and a sensor in a vessel of a patient with the catheter having a lumen extending therethrough, a proximal end, a distal end and an opening and with the sensor being within the lumen and capable of sensing a parameter of blood and providing a signal in response thereto; introducing an anti-clotting solution into the lumen from a solution-introducing system so that there is a net flow of solution into the patient; and moving blood from the vessel through the distal opening into the lumen during said step of introducing to expose the sensor to blood and obtain a signal in response to said parameter of the blood.
Claim 14
Independent Claim
122 words
A method of sensing a parameter of blood in vivo comprising: providing a catheter and a sensor in a vessel of a patient with the catheter having a lumen extending therethrough, a proximal end, a distal end and an opening and with the sensor being within the lumen and capable of sensing a parameter of blood and providing a signal in response thereto; introducing an anti-clotting solution into the lumen from a solution-introducing system so that there is a net flow of solution into the patient; and moving blood from the vessel through the distal opening into the lumen during said step of introducing to expose the sensor to blood and obtain a signal in response to said parameter of the blood.
Claim 15
Dependent Claim
63 words
A method as defined in claim 12 wherein said step of moving includes at least one of (A) moving blood back and forth in the lumen while expanding and contracting the volume of the solution-introducing system; and (B) providing the solution-introducing system with sufficient compliance so that the patient's heartbeats at least assist in said moving blood back and forth in the lumen.
Claim 16
Dependent Claim
17 words
A method as defined in claim 13 wherein said step of moving includes both (A) and (B).
Claim 17
Dependent Claim
50 words
A method as defined in claim 12 wherein said step of moving includes moving blood back and forth in the lumen while expanding and contracting the volume of the solution-introducing system, providing a volume oscillator, and causing the volume oscillator to expand and contract the volume of the solution-introducing system.
Claim 18
Dependent Claim
23 words
A method as defined in claim 12 wherein said step of moving is carried out while expanding the volume of the solution-introducing system.
Claim 19
Dependent Claim
15 words
A method as defined in claim 12 wherein said solution-introducing system has a variable volume.
Claim 20
Dependent Claim
128 words
An assembly for the in vivo measurement of a blood parameter comprising: a catheter having a lumen extending therethrough, a proximal end, a distal end and a distal opening at the distal end; a sensor for sensing the blood parameter and providing a signal in response thereto; means for mounting the sensor on the catheter with the sensor being within the lumen adjacent the distal opening; a conduit for coupling the lumen to a source of fluid whereby fluid can be supplied to the lumen; a compliant element coupled to said conduit to allow the volume of the fluid source to be expanded and contracted; and means for selectively nullifying the ability of the compliant element to allow expansion and contraction of the volume of the fluid source.
Claim 21
Dependent Claim
128 words
An assembly for the in vivo measurement of a blood parameter comprising: a catheter having a lumen extending therethrough, a proximal end, a distal end and a distal opening at the distal end; a sensor for sensing the blood parameter and providing a signal in response thereto; means for mounting the sensor on the catheter with the sensor being within the lumen adjacent the distal opening; a conduit for coupling the lumen to a source of fluid whereby fluid can be supplied to the lumen; a compliant element coupled to said conduit to allow the volume of the fluid source to be expanded and contracted; and means for selectively nullifying the ability of the compliant element to allow expansion and contraction of the volume of the fluid source.
Claim 22
Dependent Claim
27 words
An assembly as defined in claim 18 wherein said nullifying means includes means for selectively switching the compliant element into and out of communication with the conduit.
Claim 23
Dependent Claim
14 words
An assembly as defined in claim 19 wherein said switching means includes a valve.
Claim 24
Independent Claim
151 words
A method of sensing a parameter of blood in vivo comprising: providing a catheter and a sensor in a vessel of a patient with the catheter having a lumen extending therethrough, a proximal end, a distal end and an opening and with the sensor being within the lumen and capable of sensing a parameter in blood and providing a signal in response thereto; introducing an anti-clotting solution into the lumen from a solution-introducing system so that there is an interface between the blood and the solution; moving the interface back and forth in the lumen so that the sensor is exposed to blood for at least a portion of the time that the interface is moving, wherein said step of moving includes providing a compliant element and selectively switching the compliant element into and out of the solution-introducing system; and obtaining said signal from the sensor during said step of introducing.
Claim 25
Independent Claim
151 words
A method of sensing a parameter of blood in vivo comprising: providing a catheter and a sensor in a vessel of a patient with the catheter having a lumen extending therethrough, a proximal end, a distal end and an opening and with the sensor being within the lumen and capable of sensing a parameter in blood and providing a signal in response thereto; introducing an anti-clotting solution into the lumen from a solution-introducing system so that there is an interface between the blood and the solution; moving the interface back and forth in the lumen so that the sensor is exposed to blood for at least a portion of the time that the interface is moving, wherein said step of moving includes providing a compliant element and selectively switching the compliant element into and out of the solution-introducing system; and obtaining said signal from the sensor during said step of introducing.
Claim 26
Dependent Claim
24 words
A method as defined in claim 21 which further comprises taking a blood pressure reading with the compliant element out of the solution-introducing system.
Claim 27
Dependent Claim
20 words
A method as defined in claim 21 wherein said step of obtaining is carried out during said step of moving.
Claim 28
Independent Claim
145 words
A method of sensing a parameter of blood in vivo comprising: providing a catheter and a sensor in a vessel of a patient with the catheter having a lumen extending therethrough, a proximal end, a distal end and an opening and with the sensor being within the lumen and capable of sensing a parameter of blood and providing a signal in response thereto; introducing an anti-clotting solution into the lumen from a solution-introducing system so that there is a net flow of solution into the patient; and moving blood from the vessel through the distal opening into the lumen during said step of introducing to expose the sensor to blood and obtain a signal in response to said parameter of the blood, wherein said step of moving includes providing a compliant element and selectively switching the compliant element into and out of the solution-introducing system.
Claim 29
Independent Claim
145 words
A method of sensing a parameter of blood in vivo comprising: providing a catheter and a sensor in a vessel of a patient with the catheter having a lumen extending therethrough, a proximal end, a distal end and an opening and with the sensor being within the lumen and capable of sensing a parameter of blood and providing a signal in response thereto; introducing an anti-clotting solution into the lumen from a solution-introducing system so that there is a net flow of solution into the patient; and moving blood from the vessel through the distal opening into the lumen during said step of introducing to expose the sensor to blood and obtain a signal in response to said parameter of the blood, wherein said step of moving includes providing a compliant element and selectively switching the compliant element into and out of the solution-introducing system.
Claim 30
Dependent Claim
24 words
A method as defined in claim 24 which further comprises taking a blood pressure reading with the compliant element out of the solution-introducing system.
Claim 31
Independent Claim
122 words
A method of sensing a parameter of blood in vivo comprising: providing a catheter and a sensor in a vessel of a patient with the catheter having a lumen extending therethrough, a proximal end, a distal end and an opening and with the sensor being within the lumen and capable of sensing a parameter of blood and providing a signal in response thereto; introducing an anti-clotting solution into the lumen from a solution-introducing system which is under continuous pressure such that there is a net flow of solution into the patient; and moving blood from the vessel through the distal opening into the lumen to expose the sensor to blood and obtain a signal in response to said parameter of the blood.
Claim 32
Independent Claim
122 words
A method of sensing a parameter of blood in vivo comprising: providing a catheter and a sensor in a vessel of a patient with the catheter having a lumen extending therethrough, a proximal end, a distal end and an opening and with the sensor being within the lumen and capable of sensing a parameter of blood and providing a signal in response thereto; introducing an anti-clotting solution into the lumen from a solution-introducing system which is under continuous pressure such that there is a net flow of solution into the patient; and moving blood from the vessel through the distal opening into the lumen to expose the sensor to blood and obtain a signal in response to said parameter of the blood.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-06-18 | 1993-12-18 | 1994-06-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-06-18 | 1997-12-18 | 1998-06-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-06-18 | 2001-12-18 | 2002-06-19 | $7700.00 | Window Closed / Lapsed |