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US4886789A
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Peritoneal dialysis and compositions for use therein
Assignee: N M ROTHSCHILD & SONS Ltd
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Filing: 1989-04-10
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Granted: 1989-12-12
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Expires: 2009-04-10
Abstract
Abstract A peritoneal dialysis composition containing an osmotic agent comprising a glucose polymer mixture, said mixture including at least 15% by weight of glucose polymers having a D.P. (degree of polymerization) greater than 12. A method is provided for preparing the glucose polymers and a defined sterile aqueous solution of the same for use in peritoneal dialysis by introduction into the abdominal cavity. Also disclosed are methods of treating toxaemia caused by toxins arising from internal disorders of the body, such as hepatic encephalopathy, or which arise from external sources such as poisoning by overdoses of drugs or industrial and agricultural chemicals, e.g., paraquat.
Inventors
- 👤 Jeremiah Milner
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 05:39
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/14; A61M1/28; A61M1/287; A61K; A61K31/00; A61K31/70; A61K31/715; A61K31/716; A61K31/718; A61K45/00; A61K45/06
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
55 words
A method of effecting peritoneal dialysis which comprises introducing into the abdominal cavity of a patient an aqueous peritoneal dialysis composition comprising a water soluble glucose polymer mixture derived from the hydrolysis of starch containing at least 36.7% by weight of glucose polymers having a degree of polymerization (D.P.) of more than 12 glucose units.
Claim 2
Independent Claim
55 words
A method of effecting peritoneal dialysis which comprises introducing into the abdominal cavity of a patient an aqueous peritoneal dialysis composition comprising a water soluble glucose polymer mixture derived from the hydrolysis of starch containing at least 36.7% by weight of glucose polymers having a degree of polymerization (D.P.) of more than 12 glucose units.
Claim 3
Dependent Claim
20 words
The method of claim 1 wherein the average molecular weight of the glucose polymer mixture is from 15,000 to 25,000.
Claim 4
Dependent Claim
20 words
The method of claim 1 wherein the average molecular weight of the glucose polymer mixture is from 18,000 to 22,000.
Claim 5
Dependent Claim
34 words
The method of claim 1, 2 or 3 wherein the glucose polymer mixture contains more than 50% by weight of glucose polymers having a degree of polymerization (D.P.) of more than 12 glucose units.
Claim 6
Dependent Claim
35 words
The method of claim 1, 2 or 3 wherein the glucose polymer mixture contains from 50 to 90% by weight of glucose polymers having a degree of polymerization (D.P.) of more than 12 glucose units.
Claim 7
Dependent Claim
35 words
The method of claim 1, 2 or 3 wherein the glucose polymer mixture contains from 75 to 100% by weight of glucose polymers having a degree of polymerization (D.P.) of more than 12 glucose units.
Claim 8
Dependent Claim
35 words
The method of claim 1, 2 or 3 wherein the glucose polymer mixture contains from 90 to 100% by weight of glucose polymers having a degree of polymerization (D.P.) of more than 12 glucose units.
Claim 9
Dependent Claim
25 words
The method of claim 1, 2 or 3 wherein the aqueous peritoneal dialysis composition contains from 2 to 10% w/v of said glucose polymer mixture.
Claim 10
Dependent Claim
25 words
The method of claim 1, 2 or 3 wherein the aqueous peritoneal dialysis composition contains from 2 to 4% w/v of said glucose polymer mixture.
Claim 11
Dependent Claim
21 words
The method of claim 1, 2 or 3 wherein the glucose polymer mixture contains less than 3% by weight of glucose.
Claim 12
Dependent Claim
25 words
The method of claim 1, 2 or 3 wherein the aqueous peritoneal dialysis composition contains from 2 to 15% w/v of said glucose polymer mixture.
Claim 13
Dependent Claim
25 words
The method of claim 1, 2 or 3 wherein the aqueous peritoneal dialysis composition contains from 2 to 5% w/v of said glucose polymer mixture.
Claim 14
Dependent Claim
15 words
The method of claim 1, 2 or 3 wherein the patient suffers from renal failure.
Claim 15
Dependent Claim
18 words
The method of claim 1, 2 or 3 wherein the starch contains not more than 5% of 1,6-linkages.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-12-11 | 1993-06-12 | 1993-12-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-12-11 | 1997-06-12 | 1997-12-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-12-11 | 2001-06-12 | 2001-12-12 | $7700.00 | Window Closed / Lapsed |