US4885171A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Use of rapamycin in treatment of certain tumors
Assignee: Wyeth Canada Inc
•
Filing: 1984-03-22
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Granted: 1989-12-05
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Expires: 2004-03-22
Abstract
Abstract Methods for using rapamycin in the treatment of certain cancers or tumors are disclosed.
Inventors
- 👤 Sehgal N. Surendra
- 👤 Claude Vezina
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 09:17
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/44; A61K31/445; A61K31/74; A61K31/765
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
38 words
A method of treating transplanted tumors in a transplanted tumor bearing mammal, wherein said tumor is selected from lymphatic leukemia, colon, mammary, melanocarcinoma and ependymoblastoma tumors which comprises administering to said mammal an antitumor effective amount of rapamycin.
Claim 2
Independent Claim
38 words
A method of treating transplanted tumors in a transplanted tumor bearing mammal, wherein said tumor is selected from lymphatic leukemia, colon, mammary, melanocarcinoma and ependymoblastoma tumors which comprises administering to said mammal an antitumor effective amount of rapamycin.
Claim 3
Dependent Claim
12 words
The method of claim 1 wherein rapamycin is administered orally or parenterally.
Claim 4
Dependent Claim
22 words
The method of claim 2 wherein rapamycin is administered intraperitoneally as a solution in saline with a derivative of (Z)-sorbitan mono-9-octadecenoate poly(oxy-1,2-ethanediyl).
Claim 5
Dependent Claim
23 words
The method of claim 2 wherein rapamycin is administered at a daily dose of 0.5 to 500 mg per kg of body weight.
Claim 6
Dependent Claim
23 words
The method of claim 2 wherein rapamycin is administered at a daily dose of 10 to 250 mg per kg of body weight.
Claim 7
Independent Claim
24 words
The method of reducing tumor size in a colon tumor bearing mammal, comprising administering to said mammal an anti-colon tumor effective amount of rapamycin.
Claim 8
Independent Claim
24 words
The method of reducing tumor size in a colon tumor bearing mammal, comprising administering to said mammal an anti-colon tumor effective amount of rapamycin.
Claim 9
Independent Claim
26 words
The method of prolonging the survival time of a colon tumor bearing mammal, which comprises administering to said mammal an anti-colon tumor effective amount of rapamycin.
Claim 10
Independent Claim
26 words
The method of prolonging the survival time of a colon tumor bearing mammal, which comprises administering to said mammal an anti-colon tumor effective amount of rapamycin.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-12-04 | 1993-06-05 | 1993-12-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-12-04 | 1997-06-05 | 1997-12-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-12-04 | 2001-06-05 | 2001-12-05 | $7700.00 | Window Closed / Lapsed |