Abstract A ceramic-coated metal implant is used in medicine as a hemiprosthesis or endoprosthesis. A metal implant base body having at least a surface comprised of a barrier layer metal is imparted with a surface roughness of 100-400 μm by means of a mechanical and/or chemical and/or electrochemical pretreatment, thereby increasing the effective surface by more than 400%. Using anodic oxidation through spark discharge in aqueous electrolytes, an outer thickness of the roughened barrier layer metal is converted into a ceramic layer comprising oxides of the barrie layer metal and, optionally, a resorbable calcium phosphate. A maximum amount of calcium phosphate ceramic in the oxide layer faces an implantation bed of the implant. The calcium phosphate ceramic concentration decreases in the direction towards the phase boundary of the base body and oxide layer, so that bone can grow into the ceramic-coated metal implant and attain a high tenacity. In order to attain characteristics which are specific to bone, an after treatment in specific media, such as, for example, amino acids or antibiotics, can be performed. The implant can remain in place for a long period, is highly compatible with tissue and provides a large surface of bone contact, which automatically regulates bone growth in accordance with healing and growth processes.
A method of preparing an implant comprised of a ceramic-coated metal and which is highly compatible with tissue and bone, comprising texturing a surface of an implant base body which surface is comprised of a barrier layer metal to impart thereto a surface roughness of 100 to 400 μm, thereby increasing the effective surface by more than 400%, and then subjecting said barrier layer metal to anodic oxidation under spark discharge in an aqueous electrolyte solution containing calcium phosphate thereby to convert the outer 5 to 30 μm thickness thereof to a ceramic comprised 90 to 60% of oxides of the barrier layer metal and 10 to 40% of calcium phosphate and having grain dimensions of 2 to 20 μm diameter, said oxides briefly being molten during the anodic oxidation under spark discharge, the calcium phosphate being of a concentration distribution wherein the concentration decreases from a maximum at a surface of the ceramic coating to essentially zero within 1 μm of a phase boundary between the ceramic coating and underlying barrier layer metal.
Claim 2
Independent Claim
174 words
A method of preparing an implant comprised of a ceramic-coated metal and which is highly compatible with tissue and bone, comprising texturing a surface of an implant base body which surface is comprised of a barrier layer metal to impart thereto a surface roughness of 100 to 400 μm, thereby increasing the effective surface by more than 400%, and then subjecting said barrier layer metal to anodic oxidation under spark discharge in an aqueous electrolyte solution containing calcium phosphate thereby to convert the outer 5 to 30 μm thickness thereof to a ceramic comprised 90 to 60% of oxides of the barrier layer metal and 10 to 40% of calcium phosphate and having grain dimensions of 2 to 20 μm diameter, said oxides briefly being molten during the anodic oxidation under spark discharge, the calcium phosphate being of a concentration distribution wherein the concentration decreases from a maximum at a surface of the ceramic coating to essentially zero within 1 μm of a phase boundary between the ceramic coating and underlying barrier layer metal.
Claim 3
Dependent Claim
125 words
An implant which is highly biocompatible with tissue and bone, comprising a metallic base body having a textured surface comprising a barrier layer metal, said textured surface having a surface roughness of 100 to 400 μm and being ceramic-coated by the method of claim 1, such that the outer 5 to 30 μm thickness thereof are comprised of 90 to 60% of oxides of said barrier layer metal and 10 to 40% of calcium phosphate and have grain dimensions of 2 to 20 μm diameter, the calcium phosphate concentration distribution being such that said concentration decreases from a maximum at a surface of the ceramic coating to essentially zero within 1 mm of a phase boundary between said ceramic coating and said barrier layer metal.