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US4825851A Expired / Lapsed US ⏱️ 0.0 years remaining

Method for comminuting kidney stones

Assignee: Duke University
•
Filing: 1987-12-14
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Granted: 1989-05-02
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Expires: 2007-12-14
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Abstract

Abstract A method for comminuting kidney stones including treating a stone to be comminuted with a surface energy-lowering solution and applying acoustic impulses to the stone so as to pulverize the stone into fragments small enough to be passed through the ureter and urethra.

Inventors

  • 👤 Franklin H. Cocks
  • 👤 Scott R. Akers

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 07:01
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/22; A61B17/225; A61B17/22004; A61K; A61K31/00; A61K31/185; A61K31/19; A61B2017/22082; A61B2017/22084

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 85 words
A lithotripter method for comminuting kidney stones comprising: introducing a surface energy-lowering solution other than urine into a kidney through a catheter such that a stone within the kidney is exposed to said solution for at least 5 minutes; and applying at least 200 focused intense acoustic impulses to the stone after introduction of said solution; whereby the stone is comminuted into fragments small enough to be passed through the ureter and urethra with minimized risk of damage to the kidney from said acoustic impulses.
Claim 2
Dependent Claim 85 words
A lithotripter method for comminuting kidney stones comprising: introducing a surface energy-lowering solution other than urine into a kidney through a catheter such that a stone within the kidney is exposed to said solution for at least 5 minutes; and applying at least 200 focused intense acoustic impulses to the stone after introduction of said solution; whereby the stone is comminuted into fragments small enough to be passed through the ureter and urethra with minimized risk of damage to the kidney from said acoustic impulses.
Claim 3
Dependent Claim 16 words
A method according to claim 1 wherein the surface energy-lowering solution is a citric acid solution.
Claim 4
Dependent Claim 16 words
A method according to claim 2 wherein the stone to be communicated is a phosphate stone.
Claim 5
Dependent Claim 76 words
A lithotripter method for comminuting phosphate kidney stones comprising: introducing a citric acid surface energy lowering solution into a kidney through a catheter such that a stone within the kidney is exposed to said citric acid solution; and applying at least 200 focused intense acoustic impulses which produce pressure waves greater than 1 kbar in amplitude to the stone; whereby the stone is comminuted into fragments small enough to be passed through the ureter and urethra.
Claim 6
Dependent Claim 76 words
A lithotripter method for comminuting phosphate kidney stones comprising: introducing a citric acid surface energy lowering solution into a kidney through a catheter such that a stone within the kidney is exposed to said citric acid solution; and applying at least 200 focused intense acoustic impulses which produce pressure waves greater than 1 kbar in amplitude to the stone; whereby the stone is comminuted into fragments small enough to be passed through the ureter and urethra.
Claim 7
Dependent Claim 55 words
A method according to claim 4 wherein the citric acid solution comprises from about 20 to about 40 grams of citric acid, from about 2 to about 6 grams of anhydrous magnesium oxide, from about 3 to about 7 grams of anhydrous sodium carbonate and from about 800 to about 1200 cc of distilled water.
Claim 8
Dependent Claim 27 words
A method according to claim 4 wherein the stone is exposed to the citric acid solution for at least 5 minutes before the acoustic impulses are applied.

References Cited (Backward Citations)

JPS577416A Cited
JPH0219154A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-05-01 1992-10-31 1993-05-02 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-05-01 1996-10-31 1997-05-02 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-05-01 2000-10-31 2001-05-02 $7700.00 Window Closed / Lapsed

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