US4820263A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Apparatus and method for iontophoretic drug delivery
Assignee: Medtronic Inc
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Filing: 1987-11-07
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Granted: 1989-04-11
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Expires: 2007-11-07
Abstract
Abstract An ionic substance is mixed with a polar, non-ionic adhesive to form an electrode for use in the iontophoretic introduction of the ionic substance into a body. The electrode may be formed as a sheet of the mixture of a size and shape suitable for attachment to the electrode plate of an iontophoretic current generator. The mixture may be incorporated in an electrode as a means for holding the ionic substance, a means for attaching the electrode to the body, a means for attaching the iontophoretic current generator to the body, or a means for conducting the ionic current into the body. The electrode may also be employed in combination with an electrical stimulator to provide for simultaneous electrical stimulation and iontophoretic drug administration to the body.
Inventors
- 👤 Richard Spevak
- 👤 Gary A. Lattin
- 👤 Allan H. Jevne
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:13
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/02; A61N1/04; A61N1/0404; A61N1/0408; A61N1/0428; A61N1/0432; A61N1/0436; A61N1/0452; A61N1/0456
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
154 words
A device for use in iontophoretically introducing an ionic substance into body tissue through the skin of a patient, comprising: an insulative casing; a source of direct electrical current, mounted within said casing; active electrode plate means mounted on the exterior of said casing for removably mounting on said casing an active electrode element containing said ionic substance and for electrically coupling said active electrode element to said current source; indifferent electrode plate means mounted on the exterior of said casing for removably mounting on said casing an indifferent electrode element and for electrically coupling said indifferent electrode element to said current source; an adhesive active electrode element containing said ionic substance, removably mounted on said active electrode plate means; and an adhesive indifferent electrode element removably mounted on said indifferent electrode plate means; wherein said active and indifferent electrode elements are sufficiently adhesive to retain said housing on said skin of said patient.
Claim 2
Independent Claim
154 words
A device for use in iontophoretically introducing an ionic substance into body tissue through the skin of a patient, comprising: an insulative casing; a source of direct electrical current, mounted within said casing; active electrode plate means mounted on the exterior of said casing for removably mounting on said casing an active electrode element containing said ionic substance and for electrically coupling said active electrode element to said current source; indifferent electrode plate means mounted on the exterior of said casing for removably mounting on said casing an indifferent electrode element and for electrically coupling said indifferent electrode element to said current source; an adhesive active electrode element containing said ionic substance, removably mounted on said active electrode plate means; and an adhesive indifferent electrode element removably mounted on said indifferent electrode plate means; wherein said active and indifferent electrode elements are sufficiently adhesive to retain said housing on said skin of said patient.
Claim 3
Dependent Claim
19 words
A device as described in claim 1 wherein said active and indifferent electrode elements comprise sheets of adhesive materials.
Claim 4
Dependent Claim
64 words
A device as described in claim 1 wherein said active and indifferent electrode elements have first adhesive surfaces removably attaching said active and indifferent electrode elements to said active and indifferent electrode plate means, respectively, and have second adhesive surfaces opposed to said first adhesive surfaces whereby said active and indifferent electrode elements serve to attach said housing to said skin of said patient.
Claim 5
Independent Claim
151 words
A device for use in iontophoretically introducing an ionic substance into body tissue through the skin of a patient, comprising: a casing; a source of direct electrical current mounted within said casing; first electrode mounting means mounted on the exterior of said casing for mounting on said casing a first adhesive electrode element containing an ionic substance and for electrically coupling said first adhesive electrode element to said current source; second electrode mounting means mounted on the exterior of said casing for mounting on said casing a second adhesive electrode element for coupling said second adhesive electrode element to said current source; a first adhesive electrode element containing said ionic substance, mounted on said first electrode plate means; and a second adhesive electrode element mounted on said second electrode plate means; wherein said first and second electrode elements are sufficiently adhesive to retain said housing on said skin of said patient.
Claim 6
Independent Claim
151 words
A device for use in iontophoretically introducing an ionic substance into body tissue through the skin of a patient, comprising: a casing; a source of direct electrical current mounted within said casing; first electrode mounting means mounted on the exterior of said casing for mounting on said casing a first adhesive electrode element containing an ionic substance and for electrically coupling said first adhesive electrode element to said current source; second electrode mounting means mounted on the exterior of said casing for mounting on said casing a second adhesive electrode element for coupling said second adhesive electrode element to said current source; a first adhesive electrode element containing said ionic substance, mounted on said first electrode plate means; and a second adhesive electrode element mounted on said second electrode plate means; wherein said first and second electrode elements are sufficiently adhesive to retain said housing on said skin of said patient.
Claim 7
Dependent Claim
18 words
A device according to claim 4 wherein said first and second adhesive electrode elements are sheets of adhesive.
Claim 8
Dependent Claim
22 words
A device according to claim 4 wherein said first and second adhesive electrode elements are sheets fabricated of a polar, non-ionic adhesive.
Claim 9
Independent Claim
137 words
A method of iontophoretically introducing an ionic substance into a body, through the skin of the patient, comprising: selecting a source of direct electrical current of the type comprising an insulative housing and first and second electrode mounting means, said first and second electrode mounting means coupled to said source of direct electrical current; applying a first sheet of adhesive material containing said ionic substance to said first electrode mounting means; applying a second sheet of adhesive, conductive material to said second electrode mounting means; mounting said source of direct electrical current to said skin of said patient by applying said first and second sheets of adhesive material to said skin of said patient; and activating said source of direct electrical current to drive said ionic substance through said skin of said patient and into said body.
Claim 10
Independent Claim
137 words
A method of iontophoretically introducing an ionic substance into a body, through the skin of the patient, comprising: selecting a source of direct electrical current of the type comprising an insulative housing and first and second electrode mounting means, said first and second electrode mounting means coupled to said source of direct electrical current; applying a first sheet of adhesive material containing said ionic substance to said first electrode mounting means; applying a second sheet of adhesive, conductive material to said second electrode mounting means; mounting said source of direct electrical current to said skin of said patient by applying said first and second sheets of adhesive material to said skin of said patient; and activating said source of direct electrical current to drive said ionic substance through said skin of said patient and into said body.
Claim 11
Dependent Claim
133 words
A method according to claim 7 wherein said first sheet of adhesive material has opposing first and second adhesive surfaces, and wherein said step of applying said first sheet of adhesive material to said first electrode mounting means comprises adhering said first adhesive surface to said first electrode mounting means; wherein said second sheet of adhesive material has opposing first and second adhesive surfaces wherein said step of applying said second sheet of adhesive material comprises adhering said first adhesive surface of said second sheet of adhesive material to said second electrode mounting means; and wherein said step of mounting said source of direct electrical current to said skin of said patient comprises adhering said second adhesive surfaces of said first and second sheets of adhesive material to said skin of said patient.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-04-10 | 1992-10-10 | 1993-04-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-04-10 | 1996-10-10 | 1997-04-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-04-10 | 2000-10-10 | 2001-04-11 | $7700.00 | Window Closed / Lapsed |