US4767559A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for producing contact lens cleaning tablets with a disinfecting action for one-step cleaning
Assignee: LAPIS LAZULI INTERNATIONAL NV OF HOLLAND
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Filing: 1987-04-08
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Granted: 1988-08-30
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Expires: 2007-04-08
Abstract
Abstract Methods for producing a contact lens one-step cleaning and disinfecting tablet designed to be dissolved in water comprising: (A) preparing a tablettable neutralizing core mixture consisting essentially of at least one biocompatible reducing agent, at least one biocompatible catalyst, and at least one first buffering agent; (B) forming a core tablet from the mixture of step (A); (C) preparing a jacket mixture consisting essentially of at least one biocompatible cleaning and disinfecting agent and a second buffering agent; and (D) enveloping the core tablet of step (B) with the jacket mixture of step (C) so that it is completely surrounded by a stable outer layer thereof, as well as tablets produced by such methods.
Inventors
- 👤 Hans Kruse
- 👤 Jochen Jacobs
- 👤 Klaus-Dieter Wisotzki
- 👤 Jutta Thul
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 20:06
CPC Classifications
C; C11; C11D; C11D3/00; C11D3/48; A; A01; A01N; A01N25/00; A01N25/34; A61; A61L; A61L12/00; A61L12/08; A61L12/12; A61L12/124; A61L12/126; C11D17/00; C11D17/0047; C11D17/0065; C11D17/0073; C11D3/0005; C11D3/0078; C11D3/16; C11D3/38; C11D3/386; C11D3/38636
Claims Analysis
Total Claims: 33
Claim 1
Independent Claim
155 words
A method for producing a contact lens one-step cleaning and disinfecting tablet designed to be dissolved in water comprising: (A) preparing a tablettable neutralizing core mixture consisting essentially of at least one biocompatible reducing agent, and/or at least one biocompatible catalyst, and at least one first buffering agent; (B) forming a core tablet from the mixture of step (A); (C) preparing a jacket mixture consisting essentially of a biocompatible cleaning and disinfecting agent which is a hydrogen peroxide generating compound and at least one alkylglucoside of the general formula R 1 O(C n H 2n O) y (Z) x wherein R 1 is a C 8-18 alkyl, n is 2 or 3, y is 0-10, Z is glucose, and x is 1-10, and a second buffering agent; and (D) enveloping the core tablet of step (B) with the jacket mixture of step (C) so that it is completely surrounded by a stable outer layer thereof.
Claim 2
Independent Claim
155 words
A method for producing a contact lens one-step cleaning and disinfecting tablet designed to be dissolved in water comprising: (A) preparing a tablettable neutralizing core mixture consisting essentially of at least one biocompatible reducing agent, and/or at least one biocompatible catalyst, and at least one first buffering agent; (B) forming a core tablet from the mixture of step (A); (C) preparing a jacket mixture consisting essentially of a biocompatible cleaning and disinfecting agent which is a hydrogen peroxide generating compound and at least one alkylglucoside of the general formula R 1 O(C n H 2n O) y (Z) x wherein R 1 is a C 8-18 alkyl, n is 2 or 3, y is 0-10, Z is glucose, and x is 1-10, and a second buffering agent; and (D) enveloping the core tablet of step (B) with the jacket mixture of step (C) so that it is completely surrounded by a stable outer layer thereof.
Claim 3
Dependent Claim
24 words
The method of claim 1 wherein step (B) further comprises step (B1) of enveloping said core tablet with a biocompatible and water-soluble lacquer layer.
Claim 4
Dependent Claim
28 words
The method of claim 1 wherein step (B) is achieved by compressing the mixture of step (A) under a pressure of about 10,000 kilos per cm 2 .
Claim 5
Dependent Claim
28 words
The method of claim 2 wherein step (B) is achieved by compressing the mixture of step (A) under a pressure of about 10,000 kilos per cm 2 .
Claim 6
Dependent Claim
28 words
The method of claim 2 wherein said enveloping step (B1) is by coating a dense layer of said lacquer on said core tablet utilizing a rotary coating drum.
Claim 7
Dependent Claim
57 words
The method of claim 1 wherein step (D) is achieved by (a) pressing a part of said jacket layer into a matrix hole of a tabletting press, (b) introducing said core tablets into said partial layer, and (c) pressing the remainder of said jacket layer on top of the core tablet to produce a completely jacketed tablet.
Claim 8
Dependent Claim
55 words
The method of claim 2 wherein step (D) is achieved by (a) pressing a part of said jacket layer into a matrix hole of a tabletting press, (b) introducing said core tablets into said partial layer, and (c) pressing the remainder of said jacket layer on the core tablet to produce a completely jacketed tablet.
Claim 9
Dependent Claim
54 words
The method of claim 1 wherein in said core of step (A), said reducing agent is used alone and consists essentially of ascorbic acid, sodium ascorbate, glucose, or a mixture thereof, said reducing agent being present in about 1-5 mol % excess as compared with said at least one biocompatible cleaning and disinfecting agent.
Claim 10
Dependent Claim
42 words
The method of claim 1 wherein in said core of step (A), said enzyme catalyst is used alone and consists essentially of catalase, said enzyme being present in about 0.001-0.2 mg/ml based upon the quantity of said biocompatible cleaning and disinfecting agent.
Claim 11
Dependent Claim
102 words
The method of claim 1 wherein in said core of step (A), said reducing agent consists essentially of ascorbic acid, sodium ascorbate, glucose, or a mixture thereof, and is present in from one-quarter to one-half of about a 1-5 mol % excess; wherein said enzyme catalyst consists essentially of catalase and is present in about 0.001-0.2 mg/ml, the amounts of both being based upon the quantity of said biocompatible cleaning and disinfecting agent; and wherein said first buffering agent is of a type and present in an amount sufficient to effect a pH of about 7 upon the dissolution of said core.
Claim 12
Dependent Claim
66 words
The method of claim 1 wherein in said jacket of step (C), said at least one biocompatible cleaning and disinfecting agent consists essentially of at least one hydrogen peroxide generating compound and sufficient second buffering agent to adjust the pH of an aqueous solution prepared therefrom to about 2-7, both present in an amount sufficient to generate a cleaning and disinfecting effective amount of hydrogen peroxide.
Claim 13
Dependent Claim
76 words
The method of claim 1 wherein in said jacket of step (C), said at least one cleaning and disinfecting agent consists essentially of sufficient second buffering agent to adjust the pH of an aqueous solution prepared therefrom to about 2-7, and the average molecular weight ratio of said hydrogen peroxide generating compound to said alkylglucoside is about 1·10 2 to 32·10 4 :1, the combination of agents being present in a cleaning and disinfecting effective amount.
Claim 14
Dependent Claim
76 words
The method of claim 10 wherein in said jacket of step (C), said at least one cleaning and disinfecting agent consists essentially of sufficient second buffering agent to adjust the pH of an aqueous solution prepared therefrom to about 2-7, and the average molecular weight ratio of said hydrogen peroxide generating compound to said alkylglucoside is about 1·10 2 to 32·10 4 :1, the combination of agents being present in a cleaning and disinfecting effective amount.
Claim 15
Dependent Claim
51 words
The method of claim 11 wherein in said jacket of step (C), said at least one hydrogen peroxide generating compound consists essentially of urea peroxyhydrate, melamine perhydrate, potassium persulfate, or a mixture thereof, and said second buffering agent consists essentially of citric acid, salicylic acid, lactic acid, or a mixture thereof.
Claim 16
Dependent Claim
68 words
The method of claim 1 wherein in said core of step (A), said reducing agent is sodium ascorbate, said catalyst is catalase, and said first buffer is sodium hydrogen carbonate; and wherein in said jacket, said cleaning and disinfecting agent is a combination of urea peroxohydrate and/or melamine perhydrate with at least one alkylglucoside derived from a C 12-14 fatty acid with an average of 1.4 glucose moieties.
Claim 17
Dependent Claim
35 words
The method of claim 15 wherein the ingredients of said core of step (A) and/or said core tablet of step (B) is enveloped in a water-soluble continuously sealed coating of polyvinyl pyrrolidone or a polyacrylate.
Claim 18
Dependent Claim
15 words
A contact lens one-step cleaning and disinfecting tablet prepared by the method of claim 1.
Claim 19
Dependent Claim
15 words
A contact lens one-step cleaning and disinfecting tablet prepared by the method of claim 2.
Claim 20
Dependent Claim
15 words
A contact lens one-step cleaning and disinfecting tablet prepared by the method of claim 3.
Claim 21
Dependent Claim
15 words
A contact lens one-step cleaning and disinfecting tablet prepared by the method of claim 4.
Claim 22
Dependent Claim
15 words
A contact lens one-step cleaning and disinfecting tablet prepared by the method of claim 5.
Claim 23
Dependent Claim
15 words
A contact lens one-step cleaning and disinfecting tablet prepared by the method of claim 6.
Claim 24
Dependent Claim
15 words
A contact lens one-step cleaning and disinfecting tablet prepared by the method of claim 7.
Claim 25
Dependent Claim
15 words
A contact lens one-step cleaing and disinfecting tablet prepared by the method of claim 8.
Claim 26
Dependent Claim
15 words
A contact lens one-step cleaning and disinfecting tablet prepared by the method of claim 9.
Claim 27
Dependent Claim
15 words
A contact lens one-step cleaning and disinfecting tablet prepared by the method of claim 10.
Claim 28
Dependent Claim
15 words
A contact lens one-step cleaning and disinfecting tablet prepared by the method of claim 11.
Claim 29
Dependent Claim
15 words
A contact lens one-step cleaning and disinfecting tablet prepared by the method of claim 12.
Claim 30
Dependent Claim
15 words
A contact lens one-step cleaning and disinfecting tablet prepared by the method of claim 13.
Claim 31
Dependent Claim
15 words
A contact lens one-step cleaning and disinfecting tablet prepared by the method of claim 14.
Claim 32
Dependent Claim
15 words
A contact lens one-step cleaning and disinfecting tablet prepared by the method of claim 15.
Claim 33
Dependent Claim
15 words
A contact lens one-step cleaning and disinfecting tablet prepared by the method of claim 16.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-08-30 | 1992-02-29 | 1992-08-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-08-30 | 1996-02-29 | 1996-08-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-08-30 | 2000-02-29 | 2000-08-30 | $7700.00 | Window Closed / Lapsed |