Rate responsive pacing system using the integrated evoked potential

Claim 2

A cardiac pacing method which comprises the steps of: applying electrical stimulus pulses to the heart; detecting the evoked potential of said applied electrical stimulus pulses; integrating said detected potential over time to obtain a selected parameter; storing said selected parameter; comparing said selected parameter with a corresponding selected parameter of at least one previous cardiac cycle that has been stored; and controlling the rate of said electrical stimulus pulses in response to said comparison.

Claim 3

A method as described in claim 1, in which the rate controlling step includes the steps of not changing the pacing rate if the compared selected parameters are equal, varying the pacing rate in one direction if the selected parameter is less than the prior value, and varying the pacing rate in the opposite direction if the selected parameter is greater than the prior value.

Claim 4

A method as described in claim 1, wherein said selected parameter comprises the depolarization gradient duration.

Claim 5

A method as described in claim 3, including the steps of sensing the occurrence of the electrical stimulus pulse and the occurrence of the peak of the integrated evoked potential to obtain the depolarization gradient duration.

Claim 6

A method as described in claim 4, in which the controlling step includes the steps of not changing the pacing rate if the compared depolarization gradient durations are equal, increasing the pacing rate if the depolarization gradient duration is less than the prior value, and decreasing the pacing rate if the depolarization gradient duration is greater than the prior value.

Claim 7

A method as described in claim 5, in which the rate controlling step comprises the following steps: if the depolarization gradient duration is less than the prior value, then determining if the pacing rate is at a predetermined maximum; and if the pacing rate is at a predetermined maximum, then not changing the pacing rate rate, but if the pacing rate is less than said predetermined maximum then increasing the pacing rate; and if the depolarization gradient duration is greater than the prior value, then determining whether the pacing rate is at a predetermined minimum value; and if the pacing rate is at a predetermined minimum value, then not changing the pacing rate, but if the pacing rate is greater than said predetermined minimum then decreasing the pacing rate.

Claim 8

A cardiac pacing method which comprises the steps of: applying electrical stimulus pulses to the heart ventricle; detecting the evoked potential of said applied electrical stimulus pulses; integrating said detected potential over time to obtain a selected parameter; comparing said selected parameter with a target value; and controlling the rate of said electrical stimulus pulses in response to said comparison.

Claim 9

A cardiac pacing method which comprises the steps of: applying electrical stimulus pulses to the heart ventricle; detecting the evoked potential of said applied electrical stimulus pulses; integrating said detected potential over time to obtain a selected parameter; comparing said selected parameter with a target value; and controlling the rate of said electrical stimulus pulses in response to said comparison.

Claim 10

A method as described in claim 7, wherein said selected parameter comprises the depolarization gradient duration.

Claim 11

A method as described in claim 8, including the steps of sensing the occurrence of the electrical stimulus pulse and the occurrence of the peak of the integrated evoked potential to obtain the depolarization gradient duration.

Claim 12

Cardiac pacing apparatus which comprises: means for applying electrical stimulus pulses to the heart; means for detecting the evoked potential of said applied electrical stimulus pulses; means for integrating said detected potential over time to obtain a selected parameter; means for storing said selected parameter; means for comparing said selected parameter with a corresponding selected parameter of at least one previous cardiac cycle that has been stored; and means for controlling the rate of said electrical stimulus pulses in response to said comparison.

Claim 13

Cardiac pacing apparatus which comprises: means for applying electrical stimulus pulses to the heart; means for detecting the evoked potential of said applied electrical stimulus pulses; means for integrating said detected potential over time to obtain a selected parameter; means for storing said selected parameter; means for comparing said selected parameter with a corresponding selected parameter of at least one previous cardiac cycle that has been stored; and means for controlling the rate of said electrical stimulus pulses in response to said comparison.

Claim 14

Apparatus as described in claim 10, in which said controlling means includes means for maintaining the pacing rate constant if the compared selected parameters are equal, means for varying the pacing rate in one direction if the selected parameter is less than the prior value, and means for varying the pacing rate in the opposite direction if the selected parameter is greater than the prior value.

Claim 15

Apparatus as described in claim 11, including means for determining if the pacing rate is at a predetermined minimum, means for determining if the pacing rate is at a predetermined maximum, said controlling means being operable to maintain the pacing rate if the pacing rate is at one of a predetermined maximum and a predetermined minimum.

Claim 16

Cardiac pacing apparatus as described in claim 10, wherein said selected parameter comprises the depolarization gradient duration.

Claim 17

Cardiac pacing apparatus as described in claim 13, including means for sensing the occurrence of the electrical stimulus pulse and the occurrence of the peak of the integrated evoked potential, to obtain the depolarization gradient duration.

Claim 18

Apparatus as described in claim 14, in which said controlling means includes means for maintaining the pacing rate constant if the compared depolarization gradient durations are equal, means for increasing the pacing rate if the depolarization gradient duration is less than the prior value, and means for decreasing the pacing rate if the depolarization gradient duration is greater than the prior value.