US4748158A
Expired / Lapsed
US
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Alkyl glycosides as potentiating agents in antiseptic, disinfecting and cleaning preparations to increase microbicidal activity
Assignee: Henkel AG and Co KGaA
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Filing: 1985-12-06
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Granted: 1988-05-31
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Expires: 2005-12-06
Abstract
Abstract Alkyl glycosides are used to greatly increase the microbicidal activity of biguanide compounds, such as chlorhexidine salts. The alkyl glycoside/biguanide agents have a particular utility in teeth cleaning preparations due to their improved microbicidal activity against gram-positive bacteria.
Inventors
- 👤 Manfred Biermann
- 👤 Rudolf Lehmann
- 👤 Harald Schnegelberger
- 👤 Walter Ploeger
- 👤 Hans-Juergen Klueppel
- 👤 Karl-Heinz Schmid
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:03
CPC Classifications
C; C11; C11D; C11D3/00; C11D3/48; A; A01; A01N; A01N47/00; A01N47/40; A01N47/42; A01N47/44; A61; A61K; A61K31/00; A61K31/70; A61K8/00; A61K8/18; A61K8/30; A61K8/40; A61K8/43; A61K8/60; A61K8/604; A61Q; A61Q11/00
Claims Analysis
Total Claims: 29
Claim 1
Independent Claim
47 words
A microbiocidal composition comprising a microbiocidally-active combination of a biguanide compound microbiocidally active against bacteria and from about 10 to about 10,000 ppm of a C 6 - C 18 -alkyl glycoside in a non-microbiocidally-active amount which is sufficient to potentiate the microbiocidal activity of said biguanide.
Claim 2
Dependent Claim
47 words
A microbiocidal composition comprising a microbiocidally-active combination of a biguanide compound microbiocidally active against bacteria and from about 10 to about 10,000 ppm of a C 6 - C 18 -alkyl glycoside in a non-microbiocidally-active amount which is sufficient to potentiate the microbiocidal activity of said biguanide.
Claim 3
Dependent Claim
15 words
The composition as defined in claim 1, wherein the biguanide compound comprises a chlorhexidine salt.
Claim 4
Dependent Claim
21 words
The composition as defined in claim 1, wherein the amount of alkyl glycoside is in the range of about 10-2000 ppm.
Claim 5
Dependent Claim
21 words
The composition as defined in claim 1, wherein the amount of alkyl glycoside is in the range of about 50-1000 ppm.
Claim 6
Dependent Claim
24 words
The compositon as defined in claim 1, wherein the alkyl glycoside and the biguanide compound are present in substantially the same quantities by weight.
Claim 7
Dependent Claim
23 words
The composition as defined in claim 1, wherein the alkyl glycoside contains an alkyl group having from about 8 to 16 carbon atoms.
Claim 8
Dependent Claim
19 words
The composition as defined in claim 6, wherein the alkyl group contains from about 10 to 14 carbon atoms.
Claim 9
Dependent Claim
14 words
The composition as defined in claim 1, wherein the alkyl glycoside comprises a monoglycoside.
Claim 10
Dependent Claim
14 words
The composition as defined in claim 1, wherein the alkyl glycoside comprises an oligoglycoside.
Claim 11
Dependent Claim
16 words
The composition as defined in claim 9, wherein the oligoglycoside contains up to 8 glycoside residues.
Claim 12
Dependent Claim
16 words
The composition as defined in claim 9, wherein the oligoglycoside contains up to 3 glycoside residues.
Claim 13
Dependent Claim
11 words
A surface disinfection composition including the microbiocidal composition of claim 1.
Claim 14
Dependent Claim
25 words
A hygienic composition for the care of the oral cavity comprising a physiologically-compatible carrier and the microbiocidal composition of claim 1 in a microbiocidally-active amount.
Claim 15
Dependent Claim
17 words
The hygienic composition of claim 13, further including an abrasive tooth polish compatible with the biguanide compound.
Claim 16
Dependent Claim
16 words
The hygienic composition of claim 13, wherein the carrier comprises a solution of alcohol in water.
Claim 17
Dependent Claim
10 words
The hygienic composition of claim 13, further including a binder.
Claim 18
Dependent Claim
52 words
The hygienic composition of claim 13, wherein the microbiocidal composition comprises a biguanide compound present in a amount insufficient for substantial microbiocidal activity, and the C 6 -C 18 - alkyl glycoside is present in an amount sufficient to potentiate the microbiocidal activity of the biguanide compound and microbiocially-activate the microbiocidal composition.
Claim 19
Dependent Claim
17 words
The hydienic composition of claim 17, further including an abrasive tooth polish compatible with the biguanide compound.
Claim 20
Dependent Claim
12 words
The hygienic composition of claim 13, wherein the bacteria are gram-positive bacteria.
Claim 21
Dependent Claim
23 words
The hygienic composition of claim 13, wherein the alkyl glycoside is present in an amount sufficient to further function as a foaming agent.
Claim 22
Dependent Claim
20 words
The composition of claim 1, wherein the alkyl glycoside is the reaction product of a fatty alcohol and a sugar.
Claim 23
Dependent Claim
19 words
The composition of claim 1, wherein the alkyl portion of the glycoside contains an even number of carbon atoms.
Claim 24
Dependent Claim
22 words
A method for improving the hygiene of the oral cavity comprising contacting the cavity with a hygienic composition according to claim 13.
Claim 25
Dependent Claim
11 words
The method of claim 23, wherein the bacteria are gram-positive bacteria.
Claim 26
Dependent Claim
8 words
The method of claim 24, wherein the microbicidally-active
Claim 27
Dependent Claim
13 words
The method of claim 24, wherein the microbiocidally-active composition is a tooth powder.
Claim 28
Dependent Claim
12 words
The method of claim 24, wherein the microbiocidally-active composition is a mouthwash.
Claim 29
Dependent Claim
52 words
The method of claim 23, wherein the biguanide compound is present in an amount insufficient for substantial microbiocidal activity in the oral cavity and the C 6 -C 18 -alkyl glycoside is present in an amount sufficient to potentiate the microbiocidal activity of the biguanide compound and to microbiocidally activate the composition.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-05-31 | 1991-11-30 | 1992-05-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-05-31 | 1995-11-30 | 1996-05-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-05-31 | 1999-11-30 | 2000-05-31 | $7700.00 | Window Closed / Lapsed |