US4731080A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Coated intraocular lens
Assignee: Individual
•
Filing: 1986-05-20
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Granted: 1988-03-15
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Expires: 2006-05-20
Abstract
Abstract An improved intraocular lens is coated with a non-smudging biologically compatible hydrophobic crosslinked vinyl-containing silicone polymer coating material, such as polymethylvinyl siloxane or polymethylphenylvinyl siloxane. The coating material is inert, does not smudge upon contact with another surface, reduces damage on contact with the intraocular tissue, particularly the endothelium, and prevents intraocular lens induction of inflammation. The coating material or matrix preferably contains at least one optically compatible medicament which can be gradually and controllably released therefrom with time and which makes the lens suitable for implantation in both the phakic and aphakic eye. The coating material may further contain a small amount of fine particle size fumed silica.
Inventors
- 👤 Miles A. Galin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 00:41
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/14; A61F2/16; A61F2/1613; A61L; A61L27/00; A61L27/28; A61L27/34; A61L27/50; A61L27/54; A61F2/0077; A61F2002/009; A61F2250/00; A61F2250/0058; A61F2250/0067; A61L2300/00; A61L2300/20; A61L2300/21; A61L2300/23; A61L2300/232; A61L2300/40; A61L2300/404; A61L2300/41; A61L2300/42; A61L2300/60; A61L2300/602
Claims Analysis
Total Claims: 23
Claim 1
Independent Claim
27 words
An intraocular lens coated with a non-smudging biologically compatible hydrophobic crosslinked vinyl-containing silicone polymer coating material selected from the group consisting of polymethylvinyl siloxane and polymethylphenylvinyl siloxane.
Claim 2
Dependent Claim
27 words
An intraocular lens coated with a non-smudging biologically compatible hydrophobic crosslinked vinyl-containing silicone polymer coating material selected from the group consisting of polymethylvinyl siloxane and polymethylphenylvinyl siloxane.
Claim 3
Dependent Claim
43 words
An intraocular lens defined by claim 1 wherein the coating material contains at least one optically compatible medicament which can be gradually and controllably released therefrom with time and which makes the lens suitable for implantation in both the phakic and aphakic eye.
Claim 4
Dependent Claim
25 words
An intraocular lens defined by claims 1 or 2 wherein the coating constitutes from about 0.001% to about 20% by weight of the intraocular lens.
Claim 5
Dependent Claim
25 words
An intraocular lens defined by claims 1 or 2 wherein the coating has a thickness of from about 10 Å to about 10 6 Å.
Claim 6
Dependent Claim
23 words
An intraocular lens defined by claim 2 wherein the medicament constitutes from about 0.001% to about 20% by weight of the coating material.
Claim 7
Dependent Claim
19 words
An intraocular lens defined by claim 1 wherein the hydrophobic crosslinked vinyl-containing silicone polymer coating material is polymethylvinyl siloxane.
Claim 8
Dependent Claim
19 words
An intraocular lens defined by claim 1 wherein the hydrophobic crosslinked vinyl-containing silicone polymer coating material is polymethylphenylvinyl siloxane.
Claim 9
Dependent Claim
13 words
An intraocular lens defined by claim 2 wherein the medicament is an anticoagulant.
Claim 10
Dependent Claim
14 words
An intraocular lens defined by claim 2 wherein the medicament is an antiinflammatory agent.
Claim 11
Dependent Claim
14 words
An intraocular lens defined by claim 2 wherein the medicament is an anticomplement agent.
Claim 12
Dependent Claim
14 words
An intraocular lens defined by claim 2 wherein the medicament is an antibacterial agent.
Claim 13
Dependent Claim
13 words
An intraocular lens defined by claim 2 wherein the medicament is ethacrylic acid.
Claim 14
Dependent Claim
16 words
An intraocular lens defined by claim 2 wherein the coating material also contains a sulfated polysaccharide.
Claim 15
Dependent Claim
25 words
An intraocular lens defined by claim 13 wherein the sulfated polysaccharide is heparin having a molecular weight of from about 12,000 to about 15,000 daltons.
Claim 16
Dependent Claim
28 words
An intraocular lens defined by claim 13 wherein the sulfated polysaccharide is low molecular weight heparin having a molecular weight of from about 2,500 to about 5,300 daltons.
Claim 17
Dependent Claim
14 words
An intraocular lens defined by claim 13 wherein the sulfated polysaccharide is dextran sulfate.
Claim 18
Dependent Claim
14 words
An intraocular lens defined by claim 13 wherein the sulfated polysaccharide is chondroitin sulfate.
Claim 19
Dependent Claim
14 words
An intraocular lens defined by claim 13 wherein the sulfated polysaccharide is chitosan sulfate.
Claim 20
Dependent Claim
14 words
An intraocular lens defined by claim 13 wherein the sulfated polysaccharide is xylan sulfate.
Claim 21
Dependent Claim
14 words
An intraocular lens defined by claim 13 wherein the sulfated polysaccharide is a hyaluronate.
Claim 22
Dependent Claim
23 words
An intraocular lens defined by claims 1 or 2 wherein the coating material contains a small amount of fine particle size fumed silica.
Claim 23
Dependent Claim
37 words
An intraocular lens defined by claim 21 wherein the coating material contains an amount up to about 20% by weight of the coating material of fumed silica particles having an average particle size of about 12 nanometers.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-03-15 | 1991-09-14 | 1992-03-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-03-15 | 1995-09-14 | 1996-03-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-03-15 | 1999-09-14 | 2000-03-15 | $7700.00 | Window Closed / Lapsed |