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US4728323A Expired / Lapsed US ⏱️ 0.0 years remaining

Antimicrobial wound dressings

Assignee: 3M Co
•
Filing: 1986-07-24
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Granted: 1988-03-01
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Expires: 2006-07-24
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Abstract

Abstract Antimicrobial wound dressings are provided comprised of a substrate coated with an antimicrobially effective film of a silver salt. These antimicrobial wound dressings are prepared by vapor coating or sputter coating certain silver salts onto a variety of wound dressing substrates. Preferred silver salts are silver chloride and silver sulfate.

Inventors

  • 👤 Charles J. Matson

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 18:30
CPC Classifications
A; A61; A61L; A61L15/00; A61L15/07; A61L15/14; A61L15/16; A61L15/42; A61L15/46; A61L2300/00; A61L2300/10; A61L2300/102; A61L2300/104; A61L2300/40; A61L2300/404

Claims Analysis

Total Claims: 32
Claim 1
Independent Claim 54 words
An article useful as a wound dressing comprising a conformable substrate vapor coated with an antimicrobially effective film of silver chloride, said substrate having a low enough moisture vapor transmission to maintain a moist environment around the wound during healing so as to substantially prevent the formation of a hardened scab over the wound.
Claim 2
Dependent Claim 54 words
An article useful as a wound dressing comprising a conformable substrate vapor coated with an antimicrobially effective film of silver chloride, said substrate having a low enough moisture vapor transmission to maintain a moist environment around the wound during healing so as to substantially prevent the formation of a hardened scab over the wound.
Claim 3
Dependent Claim 19 words
An article according to claim 1 wherein said film is from about 50 to about 2000 Angstroms in thickness.
Claim 4
Dependent Claim 28 words
An article according to claim 1 wherein the substrate is a fabric or a polymeric film or foam having a tensile modulus of less than about 400,000 psi.
Claim 5
Dependent Claim 31 words
An article according to claim 1 wherein the substrate is selected from the group consisting of an adhesive-coated, thin film sheet, a polyurethane foam, a woven mesh and a non-woven mesh.
Claim 6
Dependent Claim 22 words
An article according to claim 1 wherein a coating of pressure-sensitive adhesive is disposed between said substrate and said antimicrobially effective film.
Claim 7
Dependent Claim 55 words
An article useful as a wound dressing comprising a conformable substrate vapor coated with an antimicrobially effective film of a silver arylsulfonate, said substrate having a low enough moisture vapor transmission to maintain a moist environment around the wound during healing so as to substantially prevent the formation of a hardened scab over the wound.
Claim 8
Dependent Claim 55 words
An article useful as a wound dressing comprising a conformable substrate vapor coated with an antimicrobially effective film of a silver arylsulfonate, said substrate having a low enough moisture vapor transmission to maintain a moist environment around the wound during healing so as to substantially prevent the formation of a hardened scab over the wound.
Claim 9
Dependent Claim 17 words
An article in accordance with claim 6 wherein said arylsulfonate is optionally substituted phenyl or naphthyl sulfonate.
Claim 10
Dependent Claim 20 words
An article in accordance with claim 6 wherein said arylsulfonate is an alkarylsulfonate having 1 to 12 aliphatic carbon atoms.
Claim 11
Dependent Claim 26 words
An article in accordance with claim 6 wherein said arylsulfonate is phenyl or naphthyl sulfonate optionally substituted with alkyl groups having 1 to 4 carbon atoms.
Claim 12
Dependent Claim 14 words
An article in accordance with claim 6 wherein said silver arylsulfonate is silver toluenesulfonate.
Claim 13
Dependent Claim 14 words
An article in accordance with claim 10 wherein said silver toluenesulfonate is silver p-toluenesulfonate.
Claim 14
Independent Claim 80 words
A method of preparing an antimicrobial wound dressing article comprising vapor coating a conformable substrate with an antimicrobially effective amount of a silver salt selected from the group consisting of silver fluoride, silver bromide, silver chloride, silver nitrate, silver sulfate, silver alkylcarboxylate, silver sulphadiazine, or silver arylsulfonate, said substrate having a low enough moisture vapor transmission to maintain a moist environment around the wound during healing so as to substantially prevent the formation of a hardened scab over the wound.
Claim 15
Independent Claim 80 words
A method of preparing an antimicrobial wound dressing article comprising vapor coating a conformable substrate with an antimicrobially effective amount of a silver salt selected from the group consisting of silver fluoride, silver bromide, silver chloride, silver nitrate, silver sulfate, silver alkylcarboxylate, silver sulphadiazine, or silver arylsulfonate, said substrate having a low enough moisture vapor transmission to maintain a moist environment around the wound during healing so as to substantially prevent the formation of a hardened scab over the wound.
Claim 16
Dependent Claim 80 words
A metod of preparing an antimicrobial wound dressing article comprising sputter coating a conformable substrate with an antimicrobially effective amount of a silver salt selected from the group consisting of silver fluoride, silver bromide, silver chloride, silver nitrate, silver sulfate, silver alkylcarboxylate, silver sulphadiazine, or silver arylsulfonate, said substrate having a low enough moisture vapor transmission to maintain a moist environment around the wound during healing so as to substantially prevent the formation of a hardened scab over the wound.
Claim 17
Dependent Claim 80 words
A metod of preparing an antimicrobial wound dressing article comprising sputter coating a conformable substrate with an antimicrobially effective amount of a silver salt selected from the group consisting of silver fluoride, silver bromide, silver chloride, silver nitrate, silver sulfate, silver alkylcarboxylate, silver sulphadiazine, or silver arylsulfonate, said substrate having a low enough moisture vapor transmission to maintain a moist environment around the wound during healing so as to substantially prevent the formation of a hardened scab over the wound.
Claim 18
Dependent Claim 54 words
An article useful as a wound dressing comprising a conformable substrate vapor coated with an antimicrobially effective film of silver sulfate, said substrate having a low enough moisture vapor transmission to maintain a moist environment around the wound during healing so as to substantially prevent the formation of a hardened scab over the wound.
Claim 19
Dependent Claim 54 words
An article useful as a wound dressing comprising a conformable substrate vapor coated with an antimicrobially effective film of silver sulfate, said substrate having a low enough moisture vapor transmission to maintain a moist environment around the wound during healing so as to substantially prevent the formation of a hardened scab over the wound.
Claim 20
Dependent Claim 55 words
An article useful as a wound dressing comprising a conformable substrate vapor coated with an antimicrobially effective film of a silver alkylcarboxylate, said substrate having a low enough moisture vapor transmission to maintain a moist environment around the wound during healing so as to substantially prevent the formation of a hardened scab over the wound.
Claim 21
Dependent Claim 55 words
An article useful as a wound dressing comprising a conformable substrate vapor coated with an antimicrobially effective film of a silver alkylcarboxylate, said substrate having a low enough moisture vapor transmission to maintain a moist environment around the wound during healing so as to substantially prevent the formation of a hardened scab over the wound.
Claim 22
Dependent Claim 14 words
An article in accordance with claim 15 wherein said silver alkylcarboxylate is silver acetate.
Claim 23
Dependent Claim 18 words
An article in accordance with claim 15 wherein said alkylcarboxylate has from 1 to 12 aliphatic carbon atoms.
Claim 24
Dependent Claim 18 words
An article in accordance with claim 15 wherein said alkylcarboxylate has from 1 to 4 aliphatic carbon atoms.
Claim 25
Dependent Claim 54 words
An article useful as a wound dressing comprising a conformable substrate vapor coated with an antimicrobially effective film of silver nitrate, said substrate having a low enough moisture vapor transmission to maintain a moist environment around the wound during healing so as to substantially prevent the formation of a hardened scab over the wound.
Claim 26
Dependent Claim 54 words
An article useful as a wound dressing comprising a conformable substrate vapor coated with an antimicrobially effective film of silver nitrate, said substrate having a low enough moisture vapor transmission to maintain a moist environment around the wound during healing so as to substantially prevent the formation of a hardened scab over the wound.
Claim 27
Dependent Claim 54 words
An article useful as a wound dressing comprising a conformable substrate vapor coated with an antimicrobially effective film of silver fluoride, said substrate having a low enough moisture vapor transmission to maintain a moist environment around the wound during healing so as to substantially prevent the formation of a hardened scab over the wound.
Claim 28
Dependent Claim 54 words
An article useful as a wound dressing comprising a conformable substrate vapor coated with an antimicrobially effective film of silver fluoride, said substrate having a low enough moisture vapor transmission to maintain a moist environment around the wound during healing so as to substantially prevent the formation of a hardened scab over the wound.
Claim 29
Dependent Claim 54 words
An article useful as a wound dressing comprising a conformable substrate vapor coated with an antimicrobially effective film of silver bromide, said substrate having a low enough moisture vapor transmission to maintain a moist environment around the wound during healing so as to substantially prevent the formation of a hardened scab over the wound.
Claim 30
Dependent Claim 54 words
An article useful as a wound dressing comprising a conformable substrate vapor coated with an antimicrobially effective film of silver bromide, said substrate having a low enough moisture vapor transmission to maintain a moist environment around the wound during healing so as to substantially prevent the formation of a hardened scab over the wound.
Claim 31
Dependent Claim 54 words
An article useful as a wound dressing comprising a conformable substrate vapor coated with an antimicrobially effective film of silver sulphadiazine, said substrate having a low enough moisture vapor transmission to maintain a moist environment around the wound during healing so as to substantially prevent the formation of a hardened scab over the wound.
Claim 32
Dependent Claim 54 words
An article useful as a wound dressing comprising a conformable substrate vapor coated with an antimicrobially effective film of silver sulphadiazine, said substrate having a low enough moisture vapor transmission to maintain a moist environment around the wound during healing so as to substantially prevent the formation of a hardened scab over the wound.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1991-03-01 1991-08-31 1992-03-01 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1995-03-01 1995-08-31 1996-03-01 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1999-03-01 1999-08-31 2000-03-01 $7700.00 Window Closed / Lapsed

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