US4721800A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Biocompatible surfaces
Assignee: Abbott Vascular Devices Ltd
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Filing: 1985-01-18
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Granted: 1988-01-26
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Expires: 2005-01-18
Abstract
Abstract A compound of formula: ##STR1## in which X 1 is a reactive group that can react to form a covalent bond with a reactive group on the surface of a material to be rendered biocompatible, X 2 is a group --O.sup.⊖ or a precursor of such a group, n is 2, 3 or 4, Y is a group --N.sup.⊕ R 3 A.sup.⊖ wherein each R, which may be the same or different, is a C 1 -C 4 alkyl group and A.sup.⊖ is an anion present when X 2 is an electrically neutral group or Y is ##STR2## wherein R 1 together with X 2 forms a direct bond between the nitrogen and the phosphorus atoms.
Inventors
- 👤 Dennis Chapman
- 👤 Aziz A. Durrani
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:05
CPC Classifications
C; C07; C07F; C07F9/00; C07F9/02; C07F9/547; C07F9/6564; C07F9/6581; C07F9/6584; C07F9/65842; C07F9/65844; A; A61; A61L; A61L33/00; A61L33/0076; A61L33/0082; C07C; C07C43/00; C07C43/30; C07C43/315; C07F5/00; C07F5/003; C07F9/06; C07F9/08; C07F9/09; C07F9/091
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
147 words
A compound of formula ##STR24## in which X 1 is ##STR25## in which each R, which may be the same or different, is a C 1 -C 4 alkyl group, y is an integer from 1 to 10 and X 3 is a reactive group that can react to form a covalent bond with a reactive group on the surface of a material to be rednered bicompatible, X 2 is a group -- O.sup.⊖ or precursor of such a group, n is 2, 3 or 4, Y is a group --N.sup.⊕ R 3 A.sup.⊖ wherein each R, which may the the same or diffreent, is a C 1 -C 4 alkyl group and A.sup.⊖ is an anion present when X 2 is an electrically neutral group or Y is ##STR26## wherein R 1 together with X 2 forms a direct bond between the nitrogen and phosphorus atoms.
Claim 2
Dependent Claim
147 words
A compound of formula ##STR24## in which X 1 is ##STR25## in which each R, which may be the same or different, is a C 1 -C 4 alkyl group, y is an integer from 1 to 10 and X 3 is a reactive group that can react to form a covalent bond with a reactive group on the surface of a material to be rednered bicompatible, X 2 is a group -- O.sup.⊖ or precursor of such a group, n is 2, 3 or 4, Y is a group --N.sup.⊕ R 3 A.sup.⊖ wherein each R, which may the the same or diffreent, is a C 1 -C 4 alkyl group and A.sup.⊖ is an anion present when X 2 is an electrically neutral group or Y is ##STR26## wherein R 1 together with X 2 forms a direct bond between the nitrogen and phosphorus atoms.
Claim 3
Dependent Claim
18 words
A compound according to claim 1 wherein, in the group X 1 , both groups R are methyl.
Claim 4
Dependent Claim
11 words
A compound according to claim 1 wherein X 3 is chlorine.
Claim 5
Dependent Claim
18 words
A compound according to claim 1 wherein Y is --N.sup.⊕ R 3 A.sup.⊖ and each R is methyl.
Claim 6
Dependent Claim
10 words
A compound according to claim 4 wherein n is 2.
Claim 7
Dependent Claim
14 words
A compound according to claim 1 wherein Y is ##STR27## and n is 2.
Claim 8
Dependent Claim
41 words
A mixture comprising at least one compound of formula (I) as defined in claim 1 wherein Y is a group --N.sup.⊕ R 3 .A.sup.⊖ and at least one compound of formula (I) as defined in claim 19 wherein Y is ##STR28##
Claim 9
Dependent Claim
33 words
A mixture according to claim 7 comprising a compound wherein Y is a group --N.sup.⊕ R 3 .A.sup.⊖ and a compound wherein Y is ##STR29## in a molar ratio of 19:1 to 4:1.
Claim 10
Dependent Claim
2 words
Choline chlorodimethylsilylphosphate.
Claim 11
Dependent Claim
2 words
Choline chlorodimethylsilylphosphate.
Claim 12
Dependent Claim
5 words
Phosphatidyl choline ethylene glycol dimethylsilylchloride.
Claim 13
Dependent Claim
5 words
Phosphatidyl choline ethylene glycol dimethylsilylchloride.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-01-25 | 1991-07-27 | 1992-01-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-01-25 | 1995-07-27 | 1996-01-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-01-25 | 1999-07-27 | 2000-01-26 | $7700.00 | Window Closed / Lapsed |