US4712558A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Electrical stimulation of muscle
Assignee: BMR Research and Development Ltd
•
Filing: 1985-03-12
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Granted: 1987-12-15
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Expires: 2005-03-12
Abstract
Abstract A method and apparatus are disclosed for the electrotrophic stimulation of muscle, that is, stimulation using pulses trains onto which information which will cause long-term functional and/or structural changes in the muscle tissue. This information is coded onto the interval between successive pulses of the series. Also disclosed is a method and apparatus for acquiring trophic data from motor unit action potential series.
Inventors
- 👤 Geoffrey Kidd
- 👤 Daniel V. Maher
- 👤 Jozef Cywinski
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 16:39
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/18; A61N1/32; A61N1/36; A61N1/36003; A61N1/36014; A61N1/3603; A61N1/36034; A61N1/36031
Claims Analysis
Total Claims: 42
Claim 1
Independent Claim
205 words
Apparatus for the stimulation of muscle fibre by the application of a stimulating electrical signal to the muscle fibre or to overlying tissue, comprising control means, pulse generating means for generating an electrical signal for use as said stimulating electrical signals and whose waveform carries information which affects the response of said muscle fibre to its stimulation by said signal and at least one pair of electrodes to be placed, in use, in electrical contact with the muscle fibre or overlying tissue, the pulse generating means being responsive in use to the control means to generate as said stimulating electrical signal a sequence of electrical pulses whose characteristics code for electrotrophic information thereby to convey electrotrophic information to the muscle fibre to bring about an electrotrophic response in said muscle fibre for effecting change in the muscle fibre to cause desired structural and/or functional adaptation of the muscle, and to supply the sequence of electrical pulses so generated to the said at least one pair of electrodes, which electrodes transmit the sequence of electrical pulses supplied by the pulse generating means to the muscle fibre or overlying tissue to impart thereto the electrotrophic stimulation to effect the desired structural and/or functional adaptation of the muscle.
Claim 2
Dependent Claim
205 words
Apparatus for the stimulation of muscle fibre by the application of a stimulating electrical signal to the muscle fibre or to overlying tissue, comprising control means, pulse generating means for generating an electrical signal for use as said stimulating electrical signals and whose waveform carries information which affects the response of said muscle fibre to its stimulation by said signal and at least one pair of electrodes to be placed, in use, in electrical contact with the muscle fibre or overlying tissue, the pulse generating means being responsive in use to the control means to generate as said stimulating electrical signal a sequence of electrical pulses whose characteristics code for electrotrophic information thereby to convey electrotrophic information to the muscle fibre to bring about an electrotrophic response in said muscle fibre for effecting change in the muscle fibre to cause desired structural and/or functional adaptation of the muscle, and to supply the sequence of electrical pulses so generated to the said at least one pair of electrodes, which electrodes transmit the sequence of electrical pulses supplied by the pulse generating means to the muscle fibre or overlying tissue to impart thereto the electrotrophic stimulation to effect the desired structural and/or functional adaptation of the muscle.
Claim 3
Dependent Claim
38 words
Apparatus according to claim 1 wherein the pulse generating means includes means for storing electrotrophic data relating to one or more specific muscles or muscle groups and for generating said sequence of pulses in accordance with said data.
Claim 4
Dependent Claim
31 words
Apparatus according to claim 2 wherein the pulse generating means further comprises translation means for translating the stored data into at least one-characteristic of the pulse signal which conveys electrotrophic information.
Claim 5
Dependent Claim
25 words
Apparatus according to claim 3 wherein the translation means comprising timing control means for translating the electrotrophic data into timing characteristics of the pulse sequence.
Claim 6
Dependent Claim
22 words
Apparatus according to claim 4 wherein the timing control means include means for setting the mark and/or space durations of successive pulses.
Claim 7
Dependent Claim
53 words
Apparatus according to claim 3 wherein the storing means comprises a number of addressable storage locations, each for storing respective time period values, the pulse generating means including means for successively reading the stored time period values and for generating pulses whose mark and/or space periods are defined by the timing period information.
Claim 8
Dependent Claim
17 words
Apparatus according to claim 3 wherein the pulse generator includes means for producing the pulses in bursts.
Claim 9
Dependent Claim
235 words
Apparatus for the stimulation of muscle fibre by the application of a stimulating electrical signal to the muscle fibre or to overlying tissue, comprising control means, pulse generating means for generating an electrical signal for use as stimulating electrical signals and whose waveform carries information which affects the response of said muscle fibre to its stimulation by said signal and at least one pair of electrodes to be placed, in use, in electrical contact with the muscle fibre or overlying tissue, the control means selectively controlling, in use, the pulse generating means to generate as said stimulating electrical signal a sequence of electrical pulses whose charateristics code electrophic information thereby to convey electrotrophic information to the muscle fibre to bring about an electrotrophic response in said muscle fibre for effecting change in the muscle fibre to cause desired structural and/or functional adaptation of the muscle, or a sequence of electrical pulses whose characteristics code Faradic information to convey Faradic information to the muscle fibre to bring about a Faradic response in said muscle fibre and to supply the sequence of electrical pulses so generated and coding the stimulating information to the said at least one pair of electrodes, which electrodes transmit the sequence of electrical pulses supplied by the pulse generating means to the muscle fibre or overlying tissue to effect the desired structural and/or functional adaption of the muscle or the Faradic stimulation respectively.
Claim 10
Dependent Claim
235 words
Apparatus for the stimulation of muscle fibre by the application of a stimulating electrical signal to the muscle fibre or to overlying tissue, comprising control means, pulse generating means for generating an electrical signal for use as stimulating electrical signals and whose waveform carries information which affects the response of said muscle fibre to its stimulation by said signal and at least one pair of electrodes to be placed, in use, in electrical contact with the muscle fibre or overlying tissue, the control means selectively controlling, in use, the pulse generating means to generate as said stimulating electrical signal a sequence of electrical pulses whose charateristics code electrophic information thereby to convey electrotrophic information to the muscle fibre to bring about an electrotrophic response in said muscle fibre for effecting change in the muscle fibre to cause desired structural and/or functional adaptation of the muscle, or a sequence of electrical pulses whose characteristics code Faradic information to convey Faradic information to the muscle fibre to bring about a Faradic response in said muscle fibre and to supply the sequence of electrical pulses so generated and coding the stimulating information to the said at least one pair of electrodes, which electrodes transmit the sequence of electrical pulses supplied by the pulse generating means to the muscle fibre or overlying tissue to effect the desired structural and/or functional adaption of the muscle or the Faradic stimulation respectively.
Claim 11
Dependent Claim
53 words
Apparatus according to claim 8 and including electrotrophic pulse generating means and functional stimulation pulse generating means, and means for selectively supplying either the electrotrophic pulse sequence or the functional stimulation pulses to the electrodes. and means for selectively supplying either the electrotrophic pulse sequence or the functional stimulation pulses to the electrodes.
Claim 12
Dependent Claim
21 words
Apparatus according to claim 8 and including means for establishing the functional stimulation to be produced by the functional stimulation pulses.
Claim 13
Dependent Claim
24 words
Apparatus according to claim 10, wherein the establishing means includes electromyographic means for examining functional stimulation pulses naturally produced by a person's nerve fibres.
Claim 14
Dependent Claim
38 words
Apparatus according to claim 8 wherein the pulse generating means includes means for storing electrotrophic data relating to one or more specific muscles or muscle groups and for generating said sequence of pulses in accordance with said data.
Claim 15
Dependent Claim
31 words
Apparatus according to claim 12 wherein the pulse generating means includes translation means to translate the stored data into at least one characteristic of the pulse signal which conveys electrotrophic information.
Claim 16
Dependent Claim
25 words
Apparatus according to claim 13 wherein the translation means comprise timing control means to translate the electrotrophic data into timing characteristics of the pulse sequence.
Claim 17
Dependent Claim
22 words
Apparatus according to claim 14 wherein the timing control means include means to set the mark and/or space durations of successive pulses.
Claim 18
Dependent Claim
53 words
Apparatus according to claim 12 wherein the storage means comprises a number of addressable storage locations, each for storing respective time period values, the pulse generating means including means for successively reading the stored time period values and for generating pulses whose mark and/or space periods are defined by the timing period information.
Claim 19
Dependent Claim
17 words
Apparatus according to claim 12 wherein the pulse generator includes means for producing the pulses in bursts.
Claim 20
Dependent Claim
17 words
Apparatus according to claim 16 wherein the pulse generator includes means for producing the pulses in bursts.
Claim 21
Independent Claim
111 words
A method of applying stimulating pulses to muscle fibre comprising generating and applying to the muscle fibres, or to overlying tissue, a stimulus pulse sequence, the pulse sequence being so selected that its waveform carries information which affects the response of said muscle fibre to its stimulation by said stimulating pulse sequence and its characteristics convey electrotrophic information to the muscle fibre for causing a desired structural and/or functional adaptation of muscle fibre of which a muscle is comprised and applying said sequence of pulses to the muscle, or to overlying tissue whereby an electrotrophic response is brought about in said muscle fibre to effect the desired structural and/or functional adaptation.
Claim 22
Independent Claim
111 words
A method of applying stimulating pulses to muscle fibre comprising generating and applying to the muscle fibres, or to overlying tissue, a stimulus pulse sequence, the pulse sequence being so selected that its waveform carries information which affects the response of said muscle fibre to its stimulation by said stimulating pulse sequence and its characteristics convey electrotrophic information to the muscle fibre for causing a desired structural and/or functional adaptation of muscle fibre of which a muscle is comprised and applying said sequence of pulses to the muscle, or to overlying tissue whereby an electrotrophic response is brought about in said muscle fibre to effect the desired structural and/or functional adaptation.
Claim 23
Dependent Claim
48 words
A method according to claim 19 and including the step of storing electrotrophic data relating to one or more specific muscles or muscle groups, reading out such data relating to a particular muscle or muscle group and generating said sequence of pulses in accordance with the read-out data.
Claim 24
Dependent Claim
28 words
A method according to claim 20 and including the step of translating the stored data into at least one characteristic of the pulse signal which conveys electrotrophic information.
Claim 25
Dependent Claim
19 words
A method according to claim 21 wherein the electrotrophic data is translated into timing characteristics of the pulse sequence.
Claim 26
Dependent Claim
19 words
A method according to claim 22 wherein the timing characteristics include the mark and/or space durations of successive pulses.
Claim 27
Dependent Claim
44 words
A method according to claim 20 wherein the storing step comprises for storing respective time period values for successive pulses to be generated in a number of addressable storage locations, the time period values of defining the mark and/or space periods of successive pulses.
Claim 28
Independent Claim
99 words
A method of applying stimulating pulses to muscle fibre comprising the steps of generating and applying to the muscle fibres, or to overlying tissue, two or more stimulus pulse sequences, a first one of the pulse sequence being so selected that the pulse sequence conveys electrotrophic information for causing a desired structural and/or functional adaptation of muscle fibre of which a muscle is comprised and applying said sequence of pulses to the muscle, or to overlying tissue and a second one of the pulse sequences being so selected as to cause a desired faradic stimulation of the muscle fibre.
Claim 29
Independent Claim
99 words
A method of applying stimulating pulses to muscle fibre comprising the steps of generating and applying to the muscle fibres, or to overlying tissue, two or more stimulus pulse sequences, a first one of the pulse sequence being so selected that the pulse sequence conveys electrotrophic information for causing a desired structural and/or functional adaptation of muscle fibre of which a muscle is comprised and applying said sequence of pulses to the muscle, or to overlying tissue and a second one of the pulse sequences being so selected as to cause a desired faradic stimulation of the muscle fibre.
Claim 30
Dependent Claim
39 words
A method according to claim 25 wherein the step of applying the two or more pulse sequences comprises applying the first and second sequences of pulses in a treatment sequence to regenerate the muscle and/or improving its mechanical performance.
Claim 31
Dependent Claim
40 words
A method according to claim 26 wherein the treatment sequence comprises applying the first and second pulse sequences a multiplicity of times, and varying, during the treatment sequence, the relative frequencies of application of the first and second pulse sequences.
Claim 32
Dependent Claim
51 words
A method according to claim 25 and including the step of storing electrotrophic and functional stimulation data relating to one or more specific muscles or muscle groups, reading out such data relating to a particular muscle or muscle group and generating said sequence of pulses in accordance with the read-out data.
Claim 33
Dependent Claim
28 words
A method according to claim 28 and including the step of translating the stored data into at least one characteristic of the pulse signal which conveys electrotrophic information.
Claim 34
Dependent Claim
19 words
A method according to claim 29 wherein the electrotrophic data is translated into timing characteristics of the pulse sequence.
Claim 35
Dependent Claim
19 words
A method according to claim 30 wherein the timing characteristics include the mark and/or space durations of successive pulses.
Claim 36
Dependent Claim
44 words
A method according to claim 28 wherein the storing step comprises for storing respective time period values for successive pulses to be generated in a number of addressable storage locations, the time period values of defining the mark and/or space periods of successive pulses.
Claim 37
Independent Claim
120 words
A method of generating a sequence of muscle stimulating pulses in accordance with pulse interval data held a memory comprising the steps of (A) reading out an item of pulse interval data from said memory; (B) initializing the contents of a memory location with data representing a count; (C) periodically incrementing or decrementing said contents; (D) periodically testing said contents and repeating (C) until said contents have a value determined in relation to the pulse interval data such that the number of repeats of (C) is determined by the pulse interval data; and (E) generating a stimulating pulse when said value occurs; steps (A) to (E) inclusive being executed for each of a series of items of pulse interval data.
Claim 38
Independent Claim
120 words
A method of generating a sequence of muscle stimulating pulses in accordance with pulse interval data held a memory comprising the steps of (A) reading out an item of pulse interval data from said memory; (B) initializing the contents of a memory location with data representing a count; (C) periodically incrementing or decrementing said contents; (D) periodically testing said contents and repeating (C) until said contents have a value determined in relation to the pulse interval data such that the number of repeats of (C) is determined by the pulse interval data; and (E) generating a stimulating pulse when said value occurs; steps (A) to (E) inclusive being executed for each of a series of items of pulse interval data.
Claim 39
Dependent Claim
47 words
A method according to claim 33 wherein in step (B) the contents of the memory location are initialized with the value of the item of pulse interval data and wherein the loop from step (D) to step (E) is excited when said contents have a predetermined value.
Claim 40
Dependent Claim
16 words
A method according to claim 33 wherein a plurality of channels of stimulating pulses are produced.
Claim 41
Dependent Claim
32 words
A method according to claim 35 wherein steps (A) to (E) inclusive are carried out for each of a plurality of channels, corresponding steps for each channel being carried out in succession.
Claim 42
Dependent Claim
32 words
A method according to claim 33 and including the step of checking whether a stimulating pulse should be produced and inhibiting the production of a stimulating pulse if it should not be.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-12-14 | 1991-06-15 | 1991-12-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-12-14 | 1995-06-15 | 1995-12-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-12-14 | 1999-06-15 | 1999-12-15 | $7700.00 | Window Closed / Lapsed |