Anti-thrombogenic blood pump

Claim 2

An anti-thrombogenic blood pump, comprising: (a) a rotor means and stator means cooperating to convey a blood stream through said pump, an interface between said rotor means and stator means being exposed to said blood stream; and (b) purge seal means including; (i) a source of blood-compatible purge fluid; (ii) a continuous passageway formed between said rotor means and stator means between said purge fluid source and said interface, said passageway having a close-clearance, substantially uniform cross section over its entire length from said purge fluid source to said interface; and (iii) means for causing said purge fluid to flow continuously and substantially uniformly through said passsageway and into said blood stream stream at said interface; (c) whereby said flow substantially pregents the accumulation of blood elements at said interface by preventing entry of blood elements into said interface.

Claim 3

The pump of claim 1, in which said rotor means and said stator means are supported for relative rotation by bearing means, and said purge seal means constitute a fluid seal between said blood stream and said bearing means.

Claim 4

The pump of claim 2, in which said purge fluid is the bearing fluid used to lubricate said bearing means.

Claim 5

The pump of claim 3, in which said bearing means are of the hydrodynamic type, and recirculating means are provided between said bearing means and said purge seal means to prevent the hydrodynamic bearing flow from inducing recirculating effects in said purge seal means.

Claim 6

The pump of claim 2, in which the flow of said purge fluid into said blood stream at said interface is just sufficient to prevent blood elements from penetrating said interface.

Claim 7

The pump of claim 2, in which said purge seal means is a cylindrical seal.

Claim 8

The pump of claim 2, in which said purge seal means is a face seal.

Claim 9

The pump of claim 2, in which said purge seal means is a spherical seal.

Claim 10

The pump of claim 2, in which said purge fluid consists of protein-free blood filtrate derived from said blood stream.

Claim 11

The blood pump of claim 9, in which said filtrate is obtained by providing protein-filtering membrane means having its high-pressure side in operative contact with said blood on the outlet side of said blood pump, and its low-pressure side in operative connectioin with said purge seal means, whereby the protein-free filtrate fluid collected on the low-pressure side of said membrane constitutes the surce of purge fluid for said purge seal means.

Claim 12

An anti-thrombogenic centrifugal blood pump, comprising: (a) a housing including an impeller chamber; (b) driving means disposed in said housing outside said impeller chamber; (c) impeller means disposed in said impeller chamber, for centrifugally pumping blood through said impeller chamber; (d) shaft means associated with said motor means and impeller means for driving said impeller means; (e) said shaft means being rotatably supported in said housing by hydrodynamic journal bearing means operating in a blood-compatible bearing fluid; (f) said shaft means and housing forming an interface at said impeller chamber; and (g) purge seal means including: (i) a source of blood-compatible purge fluid; (ii) a continuous passageway formed by said shaft means and said housing between said purge fluid source and said interface, said passageway having a close-clearance, substantially uniform cross section over its entire length from said purge fluid source to said interface; and (iii) means for causing said purge fluid to flow continuously and substantially uniformly through said passageway and into said blood stream at said interface; (h) whereby said flow substantially prevents the accumulation of blood elements at said interface.

Claim 13

An anti-thrombogenic centrifugal blood pump, comprising: (a) a housing including an impeller chamber; (b) driving means disposed in said housing outside said impeller chamber; (c) impeller means disposed in said impeller chamber, for centrifugally pumping blood through said impeller chamber; (d) shaft means associated with said motor means and impeller means for driving said impeller means; (e) said shaft means being rotatably supported in said housing by hydrodynamic journal bearing means operating in a blood-compatible bearing fluid; (f) said shaft means and housing forming an interface at said impeller chamber; and (g) purge seal means including: (i) a source of blood-compatible purge fluid; (ii) a continuous passageway formed by said shaft means and said housing between said purge fluid source and said interface, said passageway having a close-clearance, substantially uniform cross section over its entire length from said purge fluid source to said interface; and (iii) means for causing said purge fluid to flow continuously and substantially uniformly through said passageway and into said blood stream at said interface; (h) whereby said flow substantially prevents the accumulation of blood elements at said interface.

Claim 14

The pump of claim 11, in which said impeller means are shroudless.

Claim 15

The blood pump of claim 12, in which said impeller means include a hub and a plurality of blades, the surface of said hub and the wall of said impeller chamber forming an essentially continuous smooth surface at the interface between said hub means and said wall.

Claim 16

The blood pump of claim 13, in which said blades are arranged to sweep said interface as said impeller means rotate.

Claim 17

The blood pump of claim 13, in which said purge fluid flow into said impeller chamber is at a rate just sufficient to overcome the flow of blood or blood elements into said interface at all points along the interface between said shaft means and said housing.

Claim 18

The blood pump of claim 11, in which said bearing fluid and said purge fluid are the same fluid.

Claim 19

The blood pump of claim 11, further comprising plenum means surrounding said shaft means adjacent said bearing means between said bearing means and said passageway for recirculating said bearing fluid into said bearing means without affecting the flow of said purge fluid into said passageway.

Claim 20

The blood pump of claim 17, in which a low-impedance source of bearing fluid is connected to said plenum means.

Claim 21

The blood pump of claim 11, in which the clearance of said purge seal means at said interface is on the order of 2.5 μm.

Claim 22

An anti-thrombogenic axial blood pump, comprising: (a) stator means defining an elongated housing; (b) rotor means mounted for axial rotation within said housing to convey a blood stream axially of said housing, said rotor means and stator means defining between them an interface in contact with said blood stream; (c) bearing means for rotatably supporting said rotor means on said stator means; and (d) purge seal means interposed between said bearing means and said blood stream at said interface for producing an outflow of purge fluid into said blood stream at said interface sufficient to prevent penetration of blood elements into said interface; (e) said purge seal means including: (i) a source of blood-compatible purge fluid; (ii) a continuous passageway formed between said rotor means and stator means between said purge fluid source and said interface, said passageway having a substantially uniform, close-clearance cross section over its entire length from said purge fluid source to said interface, and forming a hydrodynamic bearing; and (iii) means for causing said purge fluid to flow continuously through said passageway and into said blood stream at said interface; (f) whereby by said flow substantially prevents the accumulation of blood elements at said interface while providing the bearing fluid for said hydrodynamic bearing.

Claim 23

An anti-thrombogenic axial blood pump, comprising: (a) stator means defining an elongated housing; (b) rotor means mounted for axial rotation within said housing to convey a blood stream axially of said housing, said rotor means and stator means defining between them an interface in contact with said blood stream; (c) bearing means for rotatably supporting said rotor means on said stator means; and (d) purge seal means interposed between said bearing means and said blood stream at said interface for producing an outflow of purge fluid into said blood stream at said interface sufficient to prevent penetration of blood elements into said interface; (e) said purge seal means including: (i) a source of blood-compatible purge fluid; (ii) a continuous passageway formed between said rotor means and stator means between said purge fluid source and said interface, said passageway having a substantially uniform, close-clearance cross section over its entire length from said purge fluid source to said interface, and forming a hydrodynamic bearing; and (iii) means for causing said purge fluid to flow continuously through said passageway and into said blood stream at said interface; (f) whereby by said flow substantially prevents the accumulation of blood elements at said interface while providing the bearing fluid for said hydrodynamic bearing.

Claim 24

The pump of claim 20, in which the stator and rotor surfaces adjacent said interface form an essentially continuous smooth surface swept by said blood stream.

Claim 27

The method of claim 22, further comprising the step of continually sweeping all of said points during operation of said pump.

Claim 28

The method of claim 22, further comprising the step of adjusting the flow rate of said fluid to just slightly exceed the maximum diffusion rate of elements of said blood into said interface along the perimeter of said interface.

Claim 29

The method of claim 24, further comprising the step of deriving said fluid by membrane filtration from said blood at a pressure sufficient to produce at least said adjusted flow rate of said fluid.

Claim 30

The pump of claim 1, in which the smallest cross section of said passageway is adjacent said interface.