US4680708A
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US
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Method and apparatus for analyzing electrocardiographic signals
Assignee: Washington University in St. Louis
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Filing: 1984-11-05
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Granted: 1987-07-14
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Expires: 2004-11-05
Abstract
Abstract ECG signals are digitized and a template representative of an arrhythmia free interval for a particular patient is formed. Subsequent ECG signals which match the template are averaged to form averaged ECG signals to reduce noise. A fast Fourier transform (FET) is performed on the terminal 40 millisecond portion of the QRS complex and the ST segment. The 60 db area and 40 Hz intercept of the resultant spectral output are used as a figure of merit in predicting the liklihood of a particular patient experiencing ventricular tachycardia. Alternatively, the FET magnitude is squared to form energy spectra of the ECG signals and a measure of the energy in a first preselected portion such as the 20-50 Hz region is compared with a second preselected portion such as the entire spectra to form a figure of merit for predicting ventricular tachycardia.
Inventors
- 👤 Hans D. Ambos
- 👤 Michael E. Cain
- 👤 Burton E. Sobel
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 09:29
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/24; A61B5/316; A61B5/318; A61B5/346; A61B5/349; A61B5/35; A61B5/72; A61B5/7235; A61B5/7253; A61B5/7257
Claims Analysis
Total Claims: 40
Claim 1
Independent Claim
106 words
A method for analyzing electrocardiogram (ECG) signals to determine the presence or absence of a predetermined frequency content in a preselected portion of said ECG signals comprising the steps of: converting analog ECG signals to digital ECG signals; performing a fast Fourier transform (FFT) on said preselected portion of said digital ECG signals; and determining a figure of merit (FOM) associated with the frequency content of said at least a preselected portion of said ECG signals from said output of said Fourier transform step, whereby said determination of the presence or absence of said predetermined frequency content can be determined from the vaule of said FOM.
Claim 2
Independent Claim
106 words
A method for analyzing electrocardiogram (ECG) signals to determine the presence or absence of a predetermined frequency content in a preselected portion of said ECG signals comprising the steps of: converting analog ECG signals to digital ECG signals; performing a fast Fourier transform (FFT) on said preselected portion of said digital ECG signals; and determining a figure of merit (FOM) associated with the frequency content of said at least a preselected portion of said ECG signals from said output of said Fourier transform step, whereby said determination of the presence or absence of said predetermined frequency content can be determined from the vaule of said FOM.
Claim 3
Dependent Claim
26 words
The method of claim 1 wherein said method further comprises the step of: comparing said FOM with a predetermined FOM associated with said predetermined frequency content.
Claim 4
Dependent Claim
38 words
The method of claim 2 wherein said step of determining the FOM comprises the steps of: determining the normalized power level of the FFT output at 40 Hz; and determining the 60 dB area of the FFT output.
Claim 5
Dependent Claim
26 words
The method of claim 3 wherein said method further comprises the step of forming a spectral plot of the FFT output before determining said FOM therefrom.
Claim 6
Dependent Claim
59 words
The method of claim 3 wherein said ECG signals comprises X, Y, and Z ECG signals and said step of determining said FOM further comprises: determining said FOM for each of said X, Y, and Z ECG signals; and forming the mean of said 40 Hz intercepts and said 60 dB areas from said X, Y, and Z FOM's.
Claim 7
Dependent Claim
47 words
The method of claim 3 wherein said preselected portion of said digital ECG signals comprises the terminal portion of said QRS portion and said FOM associated with said predetermined frequency content comprises a 60 dB area greater than 2400 and 40 Hz drop less than 47 dB.
Claim 8
Dependent Claim
43 words
The method of claim 3 wherein said preselected portion of said digital ECG signals comprises the ST portion and said FOM associated with said predetermined frequency content comprises a 60 dB area greater than 2500 and 40 Hz drop less than 52 dB.
Claim 9
Dependent Claim
41 words
The method of claim 1 wherein said method further comprises the step of: forming an averaged ECG signal by averaging preselected ones of said digital ECG signals before performing a FFT on at least a portion of said averaged ECG signal.
Claim 10
Dependent Claim
120 words
The method of claim 8 wherein said ECG signals comprise X, Y, and Z signals and said method further comprises the steps of: forming an averaged ECG signal for each of said X, Y, and Z signals; forming an ECG template; screening said digital ECG signals through said template to obtain said preselected ones of said digital ECG signals, said step of forming a template further comprising: selecting model X, Y, and Z signals; determining the R--R interval between successive QRS portions of a selected one of said model X, Y, and Z signals; determining the fiducial point of said selected one; and determining the peak to peak amplitude of each of said model X, Y and Z QRS portions.
Claim 11
Dependent Claim
129 words
The method of claim 9 wherein said step of screening said ECG signals comprises the steps of: choosing candidate X, Y, and Z signals for comparison with said template; performing a multi-point cross correlation between said selected one of said model X, Y, and Z signals and the corresponding one of said candidate X, Y, and Z signals; selecting said candidate X, Y, and Z signals as a portion of said preselected ones if said R--R interval of said selected one of said candidate X, Y, and Z signals is within ±20% of said template value; said cross correlation coefficient is greater than or equal to 98%; and at least two out of three of the candidate QRS peak to peak amplitudes are the same as the template values.
Claim 12
Dependent Claim
55 words
The method of claim 10 wherein said screening step further comprises selecting said candidate X, Y, and Z signals as a portion of said preselected ones of said digital ECG signals if and only if the X, Y, and Z signals before and after said chosen signal are also acceptable when compared with said template.
Claim 13
Dependent Claim
22 words
The method of claim 1 wherein said preselected portion of said ECG signals comprises the terminal 40 milliseconds of the QRS portion.
Claim 14
Dependent Claim
21 words
The method of claim 1 wherein said preselected portion of said ECG signals comprises the ST portion of the ECG signal.
Claim 15
Independent Claim
81 words
An apparatus for analyzing electrocardiogram (ECG) signals to determine the presence of a predetermined frequency content in the ECG signal comprising: A/D means for converting analog ECG signals to digital ECG signals; FFT means for performing a fast Fourier transform (FFT) on at least a portion of said digital ECG signals; and means for determining a figure of merit (FOM) for said FFT, said FOM associated with the frequency content of said at least a portion of said digital ECG signals.
Claim 16
Independent Claim
81 words
An apparatus for analyzing electrocardiogram (ECG) signals to determine the presence of a predetermined frequency content in the ECG signal comprising: A/D means for converting analog ECG signals to digital ECG signals; FFT means for performing a fast Fourier transform (FFT) on at least a portion of said digital ECG signals; and means for determining a figure of merit (FOM) for said FFT, said FOM associated with the frequency content of said at least a portion of said digital ECG signals.
Claim 17
Dependent Claim
26 words
The apparatus of claim 14 wherein said apparatus further comprises: comparison means for comparing said FOM with a predetermined FOM associated with said predetermined frequency content.
Claim 18
Dependent Claim
29 words
The apparatus of claim 15 wherein said at least a portion of said digital ECG signals comprises the terminal 40 milliseconds of a QRS portion of said ECG signals.
Claim 19
Dependent Claim
24 words
The apparatus of claim 15 wherein said at least a portion of said digital ECG signals comprises the ST segment of said ECG signal.
Claim 20
Dependent Claim
26 words
The apparatus of claim 16 wherein said predetermined FOM comprises a 60 dB area greater than 2400 and a 40 Hz intercept less than 47 dB.
Claim 21
Dependent Claim
26 words
The apparatus of claim 17, wherein said predetermined FOM comprises a 60 dB area greater than 2500 and a 40 Hz intercept less than 52 dB.
Claim 22
Independent Claim
91 words
A method for analyzing electrocardiogram (ECG) signals to determine the presence or absence of a predetermined frequency content in a preselected portion of said ECG signals comprising the steps of: converting analog ECG signals to digital ECG signals; forming energy spectra of said preselected portion of said digital ECG signals; and comparing a measure of the energy content of a first preselected portion of said energy spectra with a measure of the energy content of a second preselected portion whereby the presence or absence of a predetermined frequency content is determined.
Claim 23
Independent Claim
91 words
A method for analyzing electrocardiogram (ECG) signals to determine the presence or absence of a predetermined frequency content in a preselected portion of said ECG signals comprising the steps of: converting analog ECG signals to digital ECG signals; forming energy spectra of said preselected portion of said digital ECG signals; and comparing a measure of the energy content of a first preselected portion of said energy spectra with a measure of the energy content of a second preselected portion whereby the presence or absence of a predetermined frequency content is determined.
Claim 24
Dependent Claim
39 words
The method of claim 20 wherein the step of forming the energy spectra comprises the steps of: performing a fast-Fourier transform (FFT) on said ECG preselected portion; and squaring the magnitude of said FFT of said ECG preselected portion.
Claim 25
Dependent Claim
27 words
The method of claim 21 wherein said ECG preselected portion comprises a terminal portion of the QRS portion along with the ST portion of said ECG signals.
Claim 26
Dependent Claim
46 words
The method of claim 22 wherein the step of comparing an energy measure of the energy content comprises the step of: comparing the maximum amplitude of each frequency peak in said first preselected portion with the maximum amplitude of the largest peak in said energy spectra.
Claim 27
Dependent Claim
23 words
The method of claim 23 wherein said first preselected portion comprises approximately the region from 20 Hz to between 50 and 70 Hz.
Claim 28
Dependent Claim
45 words
The method of claim 22 wherein the step of comparing an energy measure of the energy content comprises the step of comparing the area of the energy spectra in said first preselected portion with the area of the energy spectra in said second preselected portion.
Claim 29
Dependent Claim
38 words
The method of claim 22 wherein said first preselected portion comprises approximately the region from at least 20 Hz to 50 Hz and said second preselected portion comprises approximately the the region from 0 Hz to 20 Hz.
Claim 30
Independent Claim
94 words
An apparatus for analyzing electrocardiogrm (ECG) signals to determine the presence or absence of a predetermined frequency content in a preselected portion of said ECG signals comprising: means for converting analog ECG signals to digital ECG signals; means for forming energy spectra of said preselected portion of said digital ECG signals; and means for comparing a measure of the energy content of a first preselected portion of said energy spectra with a measure of the energy content of a second preselected portion whereby the presence or absence of a predetermined frequency content is determined.
Claim 31
Independent Claim
94 words
An apparatus for analyzing electrocardiogrm (ECG) signals to determine the presence or absence of a predetermined frequency content in a preselected portion of said ECG signals comprising: means for converting analog ECG signals to digital ECG signals; means for forming energy spectra of said preselected portion of said digital ECG signals; and means for comparing a measure of the energy content of a first preselected portion of said energy spectra with a measure of the energy content of a second preselected portion whereby the presence or absence of a predetermined frequency content is determined.
Claim 32
Dependent Claim
40 words
The apparatus of claim 27 wherein said means for forming the energy spectra comprises: means for performing a fast-Fourier transform (FFT) on said ECG preselected portion; and means for squaring the magnitude of said FFT of said ECG preselected portion.
Claim 33
Dependent Claim
27 words
The apparatus of claim 28 wherein said ECG preselected portion comprises a terminal portion of the QRS portion along with the ST portion of said ECG signals.
Claim 34
Dependent Claim
44 words
The apparatus of claim 29 wherein said means for comparing an energy measure of the energy content comprises: means for comparing the area of the energy spectra in said first preselected portion with the area of the energy spectra in said second preselected portion.
Claim 35
Dependent Claim
37 words
The method of claim 29 wherein said first preselected portion comprises approximately the region from at least 20 Hz to 50 Hz and said second preselected portion comprises approximately the region from 0 Hz to 20 Hz.
Claim 36
Dependent Claim
44 words
The apparatus of claim 29 wherein means for comparing an energy measure of the energy content comprises: means for comparing the maximum amplitude of each frequency peak in said first preselected portion with the maximum amplitude of the largest peak in said energy spectra.
Claim 37
Dependent Claim
23 words
The apparatus of claim 32 wherein said first preselected portion comprises approximately the region from 20 Hz to between 50 and 70 Hz.
Claim 38
Independent Claim
125 words
An apparatus for analyzing X, Y, and Z electrocardiogram (ECG) signals to determine the presence of a predetermined frequency content thereof comprising: A/D means for converting analog X, Y, and Z ECG signals to digital ones; averaging means for averaging selected ones of each of said X, Y, and Z ECG signals for forming averaged, X, Y, and Z ECG signals; FFT means for performing a fast Fourier transform (FFT) on at least a portion of each of said averaged X, Y, and Z ECG signals; means for determining a figure of merit (FOM) from the FFT of each of said averaged X, Y, and Z ECG signals; and comparison means for comparing said FOM with a predetermined FOM associated with said predetermined frequency content.
Claim 39
Independent Claim
125 words
An apparatus for analyzing X, Y, and Z electrocardiogram (ECG) signals to determine the presence of a predetermined frequency content thereof comprising: A/D means for converting analog X, Y, and Z ECG signals to digital ones; averaging means for averaging selected ones of each of said X, Y, and Z ECG signals for forming averaged, X, Y, and Z ECG signals; FFT means for performing a fast Fourier transform (FFT) on at least a portion of each of said averaged X, Y, and Z ECG signals; means for determining a figure of merit (FOM) from the FFT of each of said averaged X, Y, and Z ECG signals; and comparison means for comparing said FOM with a predetermined FOM associated with said predetermined frequency content.
Claim 40
Dependent Claim
45 words
The apparatus of claim 34 wherein said apparatus further comprises: means for selecting said selected ones of said X, Y, and Z signals for averaging comprising means for comparing said ECG X, Y, and Z signals with a predetermined template of a model ECG signal.
References Cited (Backward Citations)
US4094308A
Cited
US4289141A
Cited
US4211237A
Cited
US4170992A
Cited
US4296755A
Cited
US4422459A
Cited
US4501279A
Cited
US4492235A
Cited
US4458691A
Cited
US4458692A
Cited
US4432375A
Cited
US4510944A
Cited
US4559602A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-07-13 | 1991-01-12 | 1991-07-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-07-13 | 1995-01-12 | 1995-07-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-07-13 | 1999-01-12 | 1999-07-14 | $7700.00 | Window Closed / Lapsed |