US4656252A
Expired / Lapsed
US
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Amidobiotin compounds useful in a avidin-biotin multiple layering process
Assignee: Individual
•
Filing: 1984-06-04
•
Granted: 1987-04-07
•
Expires: 2004-06-04
Abstract
Abstract Amidobiotin extender compounds useful, for example, in avidin-biotin multiple-layering process, which compounds include caproylamidobiotin-NHS ester, caproylamidobiotin-horse radish peroxidase, caproylamidobiotinribonuclease and caproylamidobiotin-alkaline phosphatase (B-ALP).
Inventors
- 👤 Roger W. Giese
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 09:21
CPC Classifications
B; B01; B01D; B01D67/00; B01D67/0081; B01D67/0093; B01D67/00933; A; A61; A61L; A61L27/00; A61L27/28; A61L27/34; A61L33/00; A61L33/0005; B82; B82Y; B82Y30/00; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/543; G01N33/54393; Y; Y10; Y10S; Y10S435/00; Y10S435/964; Y10S435/969; Y10S530/00; Y10S530/81; Y10S530/812; Y10S530/815; Y10S530/816
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
32 words
An amidobiotin compound having the formula: ##STR6## wherein R is an alkyl group containing 1-12 carbon atoms, a phenylene group, an alkyl-substituent phenylene group, or an alicyclic group containing 5-6 carbon atoms.
Claim 2
Dependent Claim
32 words
An amidobiotin compound having the formula: ##STR6## wherein R is an alkyl group containing 1-12 carbon atoms, a phenylene group, an alkyl-substituent phenylene group, or an alicyclic group containing 5-6 carbon atoms.
Claim 3
Dependent Claim
17 words
A compound as recited in claim 1, wherein R is an alkyl group containing 3-10 carbon atoms.
Claim 4
Dependent Claim
15 words
A compound as recited in claim 2 wherein R is (CH 2 ) 5 .
Claim 5
Dependent Claim
38 words
An amidobiotin compound having the formula: ##STR7## wherein R is an alkyl group containing 1-12 carbon atoms, a phenylene group, an alkyl-substituted phenylene group, or an alicyclic group containing 5-6 carbon atoms; and Y is a proteinaceous macromolecule.
Claim 6
Dependent Claim
38 words
An amidobiotin compound having the formula: ##STR7## wherein R is an alkyl group containing 1-12 carbon atoms, a phenylene group, an alkyl-substituted phenylene group, or an alicyclic group containing 5-6 carbon atoms; and Y is a proteinaceous macromolecule.
Claim 7
Dependent Claim
22 words
A compound as recited in claim 4 wherein R is an alkyl group containing 3-10 carbon atoms; and Y is an enzyme.
Claim 8
Dependent Claim
24 words
A compound as recited in claim 5 wherein R is (CH 2 ) 5 ; and Y is ribonuclease, horseradish peroxidase, or alkaline phosphatase.
Claim 9
Dependent Claim
49 words
An amidobiotin compound having the formula: ##STR8## wherein R 1 is an alkyl group containing 2-12 carbon atoms; R 2 is an alkyl group containing 1-12 carbon atoms, a phenylene group, an alkyl-substituted phenylene group, or an alicyclic group containing 5-6 carbon atoms; and Y is a proteinaceous macromolecule.
Claim 10
Dependent Claim
49 words
An amidobiotin compound having the formula: ##STR8## wherein R 1 is an alkyl group containing 2-12 carbon atoms; R 2 is an alkyl group containing 1-12 carbon atoms, a phenylene group, an alkyl-substituted phenylene group, or an alicyclic group containing 5-6 carbon atoms; and Y is a proteinaceous macromolecule.
Claim 11
Dependent Claim
33 words
A compound as recited in claim 7 wherein R 1 is an alkyl group containing 6 carbon atoms; R 2 is an alkyl group containing 3-10 carbon atoms; and Y is an enzyme.
Claim 12
Dependent Claim
21 words
A compound as recited in claim 8 wherein R 2 is (CH 2 ) 5 ; and Y is horseradish peroxidase.
References Cited (Backward Citations)
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