US4647671A
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Cleavable cross-linking reagent
Assignee: Harvard University
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Filing: 1985-01-25
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Granted: 1987-03-03
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Expires: 2005-01-25
Abstract
Abstract An alkali-cleavable heterobifunctional cross-linking analytical reagent is provided in the form of a compound having the structure ##STR1## in which R 1 and R 2 is each an alkylene group having from 2 to 4 carbon atoms.
Inventors
- 👤 Martin A. Schwartz
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 06:48
CPC Classifications
C; C07; C07D; C07D207/00; C07D207/02; C07D207/30; C07D207/34; C07D207/36; C07D207/40; C07D207/404; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/531; G01N33/532; G01N33/534; G01N33/58; G01N33/60
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
26 words
A compound having the structure ##STR3## in which R 1 and R 2 , is each an alkylene group having from 1 to 4 carbon atoms.
Claim 2
Dependent Claim
26 words
A compound having the structure ##STR3## in which R 1 and R 2 , is each an alkylene group having from 1 to 4 carbon atoms.
Claim 3
Dependent Claim
15 words
A compound as claimed in claim 1 in which R 1 contains two carbon atoms.
Claim 4
Dependent Claim
16 words
A compound as claimed in claim 1 in which R 2 , contains two carbon atoms.
Claim 5
Dependent Claim
12 words
A compound as claimed in claim 1 which is 1-(N-(2-hydroxy-5-azidobenzoyl)-2- aminoethyl)-4-(N-hydroxysuccinimidyl) -succinate.
Claim 6
Dependent Claim
13 words
A compound as claimed in claim 1 which is radiolabeled with iodine isotope.
Claim 7
Dependent Claim
13 words
A compound as claimed in claim 2 which is radiolabeled with iodine isotope.
Claim 8
Dependent Claim
13 words
A compound as claimed in claim 3 which is radiolabeled with iodine isotope.
Claim 9
Dependent Claim
13 words
A compound as claimed in claim 4 which is radiolabeled with iodine isotope.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-03-02 | 1990-09-01 | 1991-03-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-03-02 | 1994-09-01 | 1995-03-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-03-02 | 1998-09-01 | 1999-03-03 | $7700.00 | Window Closed / Lapsed |