US4631149A
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Antiviral eudistomins from a marine tunicate
Assignee: ILLINOIS URBANA ILL, University of, Trustees of
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Filing: 1984-02-09
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Granted: 1986-12-23
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Expires: 2004-02-09
Abstract
Abstract The subject invention concerns novel and useful antiviral compounds referred to as eudistomins. These compounds are obtainable from well-known and available marine organisms. Their utility is as antiviral agents as well as antibacterial and antitumor agents in some cases.
Inventors
- 👤 Kenneth L. Rinehart, Jr.
- 👤 Gary C. Harbour
- 👤 Jun'ichi Kobayashi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 06:28
CPC Classifications
C; C07; C07D; C07D471/00; C07D471/02; C07D471/04; C07D515/00; C07D515/12; C07D515/14
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
89 words
A compound selected from the group consisting of eudistomins C, E, K, L, F, and the acylates of C and E having the formula II: wherein the variables for each eudistomin are defined as follows: ______________________________________
Eudistomin
R R.sub.1 R.sub.2
R.sub.31
______________________________________
C H OH Br H
E Br OH H H
K H H Br H
L H Br H H
F H OH Br --COCH.sub.2 OH
C (diacetyl)
H --OCOCH.sub.3
Br --COCH.sub.3
E (diacetyl)
Br --OCOCH.sub.3
H --COCH.sub.3
______________________________________ or other carboxylic acylates or pharmaceutically acceptable salts.
Claim 2
Dependent Claim
89 words
A compound selected from the group consisting of eudistomins C, E, K, L, F, and the acylates of C and E having the formula II: wherein the variables for each eudistomin are defined as follows: ______________________________________
Eudistomin
R R.sub.1 R.sub.2
R.sub.31
______________________________________
C H OH Br H
E Br OH H H
K H H Br H
L H Br H H
F H OH Br --COCH.sub.2 OH
C (diacetyl)
H --OCOCH.sub.3
Br --COCH.sub.3
E (diacetyl)
Br --OCOCH.sub.3
H --COCH.sub.3
______________________________________ or other carboxylic acylates or pharmaceutically acceptable salts.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-12-22 | 1990-06-23 | 1990-12-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-12-22 | 1994-06-23 | 1994-12-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-12-22 | 1998-06-23 | 1998-12-23 | $7700.00 | Window Closed / Lapsed |