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US4623330A Expired / Lapsed US ⏱️ 0.0 years remaining

Gas diffusion-limited controlled release devices

Assignee: Commonwealth Scientific and Industrial Research Organisation
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Filing: 1983-02-16
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Granted: 1986-11-18
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Expires: 2003-02-16
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Abstract

Abstract A device for controllably delivering a solid, paste or liquid material in biological, environmental or industrial systems. The device is in the form of a tubular body, one end of which is open to allow egress of the material, and the other is closed. A gas-tight plunger slides within the body by virtue of spring driving means and gas from the external environment which enters the closed end of the tubular body by way of a gas permeable membrane and acts, together with the spring on the rear face of the plunger. The plunger controllably ejects the material from the open end of the device. The device has particular use in the delivery of therapeutic and/or prophylatic materials to animals.

Inventors

  • 👤 Ralph H. Laby
  • 👤 Bruno Kautzner

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-22 20:22
CPC Classifications
B; B65; B65D; B65D83/00; B65D83/76; B65D83/766

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 222 words
A device for delivering a solid or liquid paste material at a controlled rate comprising a hollow tubular body having one end which is at least partially open and another end which is closed, a gas tight plunger located inside the body so as to be capable of slidable movement within the body, the plunger comprising a disc of waxy solid material having lubricating properties which decreases the yield stress and frictional resistance between the plunger and the body, compression means for providing compressive forces on the disc in the axial direction, thereby urging the disc to expand radially and a spring means under compression located between the closed end and the plunger for urging the plunger towards the open end as the spring means expands, said material being locatable between the plunger and open end so that movement of the plunger towards the open end dispenses material through the open end of the device, wherein said device is provided with a gas permeable membrane at or adjacent the closed end of the body, such that gas from outside of the body may diffuse through the membrane internally into the body behind the plunger at a controlled rate to thereby control movement of the plunger under the influence of the spring means to dispense the material at a controlled rate in use.
Claim 2
Independent Claim 222 words
A device for delivering a solid or liquid paste material at a controlled rate comprising a hollow tubular body having one end which is at least partially open and another end which is closed, a gas tight plunger located inside the body so as to be capable of slidable movement within the body, the plunger comprising a disc of waxy solid material having lubricating properties which decreases the yield stress and frictional resistance between the plunger and the body, compression means for providing compressive forces on the disc in the axial direction, thereby urging the disc to expand radially and a spring means under compression located between the closed end and the plunger for urging the plunger towards the open end as the spring means expands, said material being locatable between the plunger and open end so that movement of the plunger towards the open end dispenses material through the open end of the device, wherein said device is provided with a gas permeable membrane at or adjacent the closed end of the body, such that gas from outside of the body may diffuse through the membrane internally into the body behind the plunger at a controlled rate to thereby control movement of the plunger under the influence of the spring means to dispense the material at a controlled rate in use.
Claim 3
Dependent Claim 21 words
A controlled release device as claimed in claim 1, wherein the disc of waxy material having lubricating properties is stearylamine diethoxylate.
Claim 4
Dependent Claim 38 words
A controlled release device as claimed in claim 1, wherein the compression means comprises two essentially rigid plates which are slightly smaller in diameter than the lubricant disc which is clamped between the plates by a spring mechanism.
Claim 5
Dependent Claim 32 words
A controlled release device as claimed in claim 1, wherein the gas diffusion membrane is composed of a material selected from the group consisting of polypropylene polyethylene, natural rubber, polyvinylchloride and silicone.
Claim 6
Dependent Claim 29 words
A controlled release device as claimed in claim 1 and adapted to contain a liquid, said device including a non-return valve in the open end of the tubular body.
Claim 7
Dependent Claim 91 words
A controlled release device as claimed in claim 1 further including a resilient member connected to the tubular body of the device, said resilient member being resiliently deformable between a first configuration to a second configuration thereby to facilitate administration of the device to an animal when in the second configuration and wherein when the device reaches the desired location within the animal after administration, the resilient member is capable of reverting to the first configuration so as to substantially reduce the possibility of expulsion of the device from the animal.
Claim 8
Dependent Claim 24 words
A controlled release device as claimed in claim 1, wherein said gas permeable membrane comprises the walls of the body adjacent the closed end.
Claim 9
Independent Claim 241 words
A device for delivering a solid or liquid paste material at a controlled rate comprising a hollow tubular body having one end which is at least partially open and another end which is closed, a gas tight plunger located inside the body so as to be capable of slidable movement within the body, the plunger comprising an elastic or resilient moulded material containing a waxy lubricant having lubricating properties which decreases the yield stress and frictional resistance between the plunger and the body, compression means for providing compressive forces on the elastic or resilient moulded material containing the waxy lubricant so that the waxy lubricant is forced to expand radially against the inside walls of the tubular body and a spring means under compression located between the closed end and the plunger for urging the plunger towards the open end as the spring means expands, said material being locatable between the plunger and open end so that movement of the plunger towards the open end dispenses material through the open end of the device, wherein said device is provided with a gas permeable membrane at or adjacent the closed end of the body, such that gas from outside of the body may diffuse through the membrane internally into the body behind the plunger at a controlled rate to thereby control movement of the plunger under the influence of the spring means to dispense the material at a controlled rate in use.
Claim 10
Independent Claim 241 words
A device for delivering a solid or liquid paste material at a controlled rate comprising a hollow tubular body having one end which is at least partially open and another end which is closed, a gas tight plunger located inside the body so as to be capable of slidable movement within the body, the plunger comprising an elastic or resilient moulded material containing a waxy lubricant having lubricating properties which decreases the yield stress and frictional resistance between the plunger and the body, compression means for providing compressive forces on the elastic or resilient moulded material containing the waxy lubricant so that the waxy lubricant is forced to expand radially against the inside walls of the tubular body and a spring means under compression located between the closed end and the plunger for urging the plunger towards the open end as the spring means expands, said material being locatable between the plunger and open end so that movement of the plunger towards the open end dispenses material through the open end of the device, wherein said device is provided with a gas permeable membrane at or adjacent the closed end of the body, such that gas from outside of the body may diffuse through the membrane internally into the body behind the plunger at a controlled rate to thereby control movement of the plunger under the influence of the spring means to dispense the material at a controlled rate in use.

References Cited (Backward Citations)

US1737844A Cited
US2809774A Cited
US3604417A Cited
US4389202A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1989-11-17 1990-05-19 1990-11-18 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1993-11-17 1994-05-19 1994-11-18 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1997-11-17 1998-05-19 1998-11-18 $7700.00 Window Closed / Lapsed

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