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US4614190A Expired / Lapsed US ⏱️ 0.0 years remaining

Photoradiation method and arrangement

Assignee: INNOVATIVE HEALTH CONCEPTS Inc
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Filing: 1982-09-08
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Granted: 1986-09-30
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Expires: 2002-09-08
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Abstract

Abstract A method and arrangement for activating a photoirradiable chemical such as hematoporphyrin derivative (HPD) particularly in vivo by use of pulsed radiation of the required frequency higher energy input with less damage surrounding tissue can be achieved.

Inventors

  • 👤 Alexei Stanco
  • 👤 James A. Piper

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 00:58
CPC Classifications
A; A61; A61K; A61K41/00; A61K41/0057; A61K41/0071; A61N; A61N5/00; A61N5/06; A61N2005/0658; A61N2005/0662; A61N5/0613; A61N5/062

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 97 words
A method for treating living tissue, wherein the tissue contains an administered hematoporphyrin derivative for sensitizing the tissue to irradiation treatment, the method comprising the step of irradiating the tissue with pulsed electromagnetic energy from a laser having a wave length in the range of 626 to 636 nanometers, the energy having a power level with a peak value on the order of tens of kilowatts, but an average value only on the order of several watts, the peak value being sufficient to activate the hematoporphyrin derivative, but too small to effect general deterioration of surrounding tissue.
Claim 2
Independent Claim 97 words
A method for treating living tissue, wherein the tissue contains an administered hematoporphyrin derivative for sensitizing the tissue to irradiation treatment, the method comprising the step of irradiating the tissue with pulsed electromagnetic energy from a laser having a wave length in the range of 626 to 636 nanometers, the energy having a power level with a peak value on the order of tens of kilowatts, but an average value only on the order of several watts, the peak value being sufficient to activate the hematoporphyrin derivative, but too small to effect general deterioration of surrounding tissue.
Claim 3
Dependent Claim 22 words
A method according to claim 1, wherein the electromagnetic radiation has a pulse length in the range of 20 to 50 nanoseconds.
Claim 4
Independent Claim 22 words
A method according to claims 1 or 2, wherein the pulse frequency is in the range of 100 hertz to 10 kilohertz.
Claim 5
Dependent Claim 19 words
A method according to claim 1, comprising the step of emitting the electromagnetic energy from a gold vapor laser.
Claim 6
Dependent Claim 35 words
A method according to claim 1, further comprising the step of coupling the electromagnetic energy emitted from the laser into at least one optical fiber for delivery of the energy to a tissue treatment site.

References Cited (Backward Citations)

SU581941A1 Cited
US3914013A Cited
US3900034A Cited
US4309998A Cited
US4266549A Cited
US4391275A Cited
US4336809A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1989-09-29 1990-03-31 1990-09-30 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1993-09-29 1994-03-31 1994-09-30 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1997-09-29 1998-03-31 1998-09-30 $7700.00 Window Closed / Lapsed

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