US4610993A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Use of selected pyridine-N-oxide disulfide compounds to treat or prevent bovine mastitis
Assignee: Olin Corp
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Filing: 1984-08-08
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Granted: 1986-09-09
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Expires: 2004-08-08
Abstract
Abstract Described is a method for treating an animal for bovine mastitis wherein said animal is administered an effective amount of at least one selected pyridine-N-oxide disulfide compound to treat or prevent bovine mastitis.
Inventors
- 👤 John H. Wedig
- 👤 John G. Babish
- 👤 Jeffrey Davidson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 11:20
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/44
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
98 words
A method of treating an animal for bovine mastitis which comprises administering to said animal an effective amount of at least one pyridine-N-oxide disulfide compound to treat or prevent bovine mastitis, said pyridine-N-oxide disulfide compound selected from the group consisting of (a) 2,2'-dithiobis-pyridine-1,1'-dioxide; and (b) adducts of 2,2'-dithiobis-pyridine-1,1'-dioxide, the adducts having the formula: (C.sub.5 H.sub.4 NOS).sub.2 MY.sub.t wherein M is an alkaline earth metal selected from the group consisting of calcium, magnesium, barium and strontium; Y is an anion selected from the group consisting of halides, sulfates, nitrates, chlorates and acetates; and t is either 1 or 2.
Claim 2
Independent Claim
98 words
A method of treating an animal for bovine mastitis which comprises administering to said animal an effective amount of at least one pyridine-N-oxide disulfide compound to treat or prevent bovine mastitis, said pyridine-N-oxide disulfide compound selected from the group consisting of (a) 2,2'-dithiobis-pyridine-1,1'-dioxide; and (b) adducts of 2,2'-dithiobis-pyridine-1,1'-dioxide, the adducts having the formula: (C.sub.5 H.sub.4 NOS).sub.2 MY.sub.t wherein M is an alkaline earth metal selected from the group consisting of calcium, magnesium, barium and strontium; Y is an anion selected from the group consisting of halides, sulfates, nitrates, chlorates and acetates; and t is either 1 or 2.
Claim 3
Dependent Claim
18 words
The method of claim 1 wherein the administration is effected to the teats and udder of a cow.
Claim 4
Dependent Claim
36 words
The method of claim 2 wherein from 1 to about 4 doses of about 25 to about 1000 milligrams of 2,2'-dithiobis-pyridine-1,1'-dioxide are infused into each teat of said cow at intervals of 12 to 48 hours.
Claim 5
Dependent Claim
24 words
The method of claim 3 wherein from about 25 to about 100 milligrams of said 2,2'-dithiobis-pyridine-1,1'-dioxide are infused into each teat of said cow.
Claim 6
Dependent Claim
24 words
The method of claim 2 wherein an effective amount of 2,2'-dithiobis-pyridine-1,1'-dioxide is applied to the outside of the teats and udder of a cow.
Claim 7
Dependent Claim
42 words
The method of claim 2 wherein from 1 to about 4 doses of about 25 to about 1000 milligrams of the magnesium sulfate trihydrate adduct of 2,2'-dithiobis-pyridine-1,1'-dioxide are infused into each teat of said cow at intervals of 12 to 48 hours.
Claim 8
Dependent Claim
29 words
The method of claim 6 wherein from about 25 to about 100 milligrams of said magnesium sulfate trihydrate adduct of 2,2'-dithiobis-pyridine-1,1'-dioxide are infused into each teat of said cow.
Claim 9
Dependent Claim
29 words
The method of claim 2 wherein an effective amount of magnesium sulfate trihydrate adduct of 2,2'-dithiobis-pyridine-1,1'-dioxide is applied to the outside of the teats and udder of a cow.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-09-08 | 1990-03-10 | 1990-09-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-09-08 | 1994-03-10 | 1994-09-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-09-08 | 1998-03-10 | 1998-09-09 | $7700.00 | Window Closed / Lapsed |