US4599326A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Acetyl erythromycin stearate, and compositions containing it
Assignee: Orion Oyj
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Filing: 1984-12-27
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Granted: 1986-07-08
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Expires: 2004-12-27
Abstract
Abstract The invention relates to a new antibiotic compound, acetyl erythromycin stearate having formula I ##STR1## The compound according to the invention is absorbed readily from the alimentary tract. Gastric acid does not convert the compound according to the invention to an uneffective form as is the case with some other erythromycin antibiotics. Absorbing is good also when the patient eats when taking the new medicine. The compound according to the invention is prepared by reacting erythromycin base with acetyl halide in an organic solvent in the presence of an acid acceptor. The stearate salt is prepared from the obtained ester without in between isolating the ester.
Inventors
- 👤 Martti L. A. Marvola
- 👤 Esko V. Marttila
- 👤 Jaakko A. Uotila
- 👤 Aino K. Pippuri
- 👤 Pekka J. Kairisalo
- 👤 Erkki J. Honkanen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 05:06
CPC Classifications
C; C07; C07H; C07H17/00; C07H17/04; C07H17/08; A; A61; A61P; A61P31/00; A61P31/04
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
11 words
An antibiotic compound, acetyl erythromycin stearate, having the formula I ##STR3##
Claim 2
Dependent Claim
11 words
An antibiotic compound, acetyl erythromycin stearate, having the formula I ##STR3##
Claim 3
Dependent Claim
37 words
An antibiotic composition, comprising about 196.5 mg to about 393 mg acetyl erythromycin stearate as well as one or more ingredients selected from the group: liquid or solid carriers, fillers, lubricants and other ancillary or additive ingredients.
Claim 4
Dependent Claim
37 words
An antibiotic composition, comprising about 196.5 mg to about 393 mg acetyl erythromycin stearate as well as one or more ingredients selected from the group: liquid or solid carriers, fillers, lubricants and other ancillary or additive ingredients.
Claim 5
Dependent Claim
30 words
An antibiotic composition according to claim 2, comprising one or several ingredients selected from the group: polyvinyl pyrrolidone, microcrystalline cellulose, modified cellulose gum, corn starch, granulated sugar and magnesium stearate.
References Cited (Backward Citations)
US4150220A
Cited
US4349545A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-07-07 | 1990-01-06 | 1990-07-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-07-07 | 1994-01-06 | 1994-07-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-07-07 | 1998-01-06 | 1998-07-08 | $7700.00 | Window Closed / Lapsed |