US4558070A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Acid salts of valproic acid
Assignee: Abbott Laboratories
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Filing: 1983-10-26
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Granted: 1985-12-10
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Expires: 2003-10-26
Abstract
Abstract Acid salts of valproic acid having the structure: ##STR1## wherein M is potassium, cesium or rubidium. The salts of the invention are useful in the treatment of epileptic seizures, and can be conveniently formulated into oral dosage forms.
Inventors
- 👤 John F. Bauer
- 👤 Douglas M. Shada
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 10:44
CPC Classifications
C; C07; C07C; C07C53/00; C07C53/126; C07C53/128; A; A61; A61P; A61P25/00; A61P25/08
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
27 words
A compound of the formula M Valproate 0.3 Valproic Acid wherein M is an alkali metal ion selected from the group consisting of K, Cs and Rb.
Claim 2
Dependent Claim
27 words
A compound of the formula M Valproate 0.3 Valproic Acid wherein M is an alkali metal ion selected from the group consisting of K, Cs and Rb.
Claim 3
Dependent Claim
11 words
A compound as defined in claim 1 wherein M is potassium.
Claim 4
Dependent Claim
48 words
An oral pharmaceutical dosage form for treating epileptic seizures or convulsions containing an effective amount of a compound of the formula: M Valproate 0.3 Valproic Acid wherein M is an alkali metal ion selected from the group consisting of K, Cs and Rb and a pharmaceutically acceptable diluent.
Claim 5
Dependent Claim
48 words
An oral pharmaceutical dosage form for treating epileptic seizures or convulsions containing an effective amount of a compound of the formula: M Valproate 0.3 Valproic Acid wherein M is an alkali metal ion selected from the group consisting of K, Cs and Rb and a pharmaceutically acceptable diluent.
Claim 6
Dependent Claim
13 words
An oral dosage form as defined in claim 3 wherein M is potassium.
Claim 7
Independent Claim
52 words
A method of treating epileptic seizures or convulsions which comprises administering to a patient in need of such treatment a therapeutically effective amount of a compound of the formula: ##STR6## M Valproate 0.3 Valproic Acid, wherein M is an alkali metal ion selected from the group consisting of K, Cs and Rb.
Claim 8
Independent Claim
52 words
A method of treating epileptic seizures or convulsions which comprises administering to a patient in need of such treatment a therapeutically effective amount of a compound of the formula: ##STR6## M Valproate 0.3 Valproic Acid, wherein M is an alkali metal ion selected from the group consisting of K, Cs and Rb.
References Cited (Backward Citations)
FR1074978A
Cited
FR2442M
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-12-09 | 1989-06-10 | 1989-12-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-12-09 | 1993-06-10 | 1993-12-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-12-09 | 1997-06-10 | 1997-12-10 | $7700.00 | Window Closed / Lapsed |