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US4553553A Expired / Lapsed US ⏱️ 0.0 years remaining

Device for the detection of bacteria, fungi, and viruses in blood

Assignee: Roche Diagnostics GmbH
•
Filing: 1983-03-07
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Granted: 1985-11-19
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Expires: 2003-03-07
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Abstract

Abstract A device used in detecting bacteria, fungi, and viruses in blood circulated through a particulate adsorbent material initially in a housing has a piston for pushing the adsorbent material from the housing for the detection. The piston preferably provides one passage for circulating the blood through the adsorbent material in the housing. An O-ring on the piston preferably indicates when the device has been used.

Inventors

  • 👤 Ernst Homann
  • 👤 Michael Nelboeck
  • 👤 Klaus Schlieder
  • 👤 Gernold Bayer

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 17:55
CPC Classifications
C; C12; C12M; C12M23/00; C12M23/02; C12M23/10

Claims Analysis

Total Claims: 17
Claim 1
Independent Claim 171 words
In a device for use in the detection of at least one of bacteria, fungi, and viruses in blood, the device having a housing, particulate adsorbent capable of binding at least one of the bacteria, fungi, and viruses from blood flowing therethrough and suitable for subsequent use in at least one of bacteriological, virological, mycological, and electron-microscopic investigations in the housing, and means for connecting the housing into an extracorporeal blood circulation in such a way that the blood flows through the particulate adsorbant in the housing, the improvement comprising: a piston rod movably projecting through one side of the housing; piston means on the piston rod and in the housing for forcing at least part of the particulate adsorbent out of the housing; and a removable cover on another side of the housing such that, when the cover is removed and the piston rod moved into the housing, the piston means forces at least part of the particulate adsorbent out of the housing, whereby it is available for the investigations.
Claim 2
Dependent Claim 171 words
In a device for use in the detection of at least one of bacteria, fungi, and viruses in blood, the device having a housing, particulate adsorbent capable of binding at least one of the bacteria, fungi, and viruses from blood flowing therethrough and suitable for subsequent use in at least one of bacteriological, virological, mycological, and electron-microscopic investigations in the housing, and means for connecting the housing into an extracorporeal blood circulation in such a way that the blood flows through the particulate adsorbant in the housing, the improvement comprising: a piston rod movably projecting through one side of the housing; piston means on the piston rod and in the housing for forcing at least part of the particulate adsorbent out of the housing; and a removable cover on another side of the housing such that, when the cover is removed and the piston rod moved into the housing, the piston means forces at least part of the particulate adsorbent out of the housing, whereby it is available for the investigations.
Claim 3
Dependent Claim 48 words
A device as in claim 1, wherein the piston means tapers toward the piston rod, and further comprising an O-ring so placed on the taper as to slip off irreversibly when the piston means is moved into the housing, whereby to indicate that the device has been used.
Claim 4
Dependent Claim 45 words
A device as in claim 1, wherein the piston rod has a pasage therethrough from outside to inside the housing at least before the piston rod is moved, the passage forming a part of the means for connecting the housing into the extracorporeal blood circulation.
Claim 5
Dependent Claim 48 words
A device as in claim 3, wherein the piston means tapers toward the piston rod, and further comprising an O-ring so placed on the taper as to slip off irreversibly when the piston means is moved into the housing, whereby to indicate that the device has been used.
Claim 6
Dependent Claim 15 words
A device as in claim 3, wherein the passage extends longitudinally throughout the piston rod.
Claim 7
Dependent Claim 56 words
A device as in claim 4, and further comprising three way valve means connected to the means for connecting the housing into the extracorporeal blood circulation for so connecting the housing, for switching the circulation to the housing to at least one of a flushing agent and nutrient broth, and for stopping circulation to the housing.
Claim 8
Dependent Claim 48 words
A device as in claim 5, wherein the piston means tapers toward the piston rod, and further comprising an O-ring so placed on the taper as to slip off irreversibly when the piston means is moved into the housing, whereby to indicate that the device has been used.
Claim 9
Dependent Claim 37 words
A device as in claim 4, wherein the passage terminates in the piston means, and wherein the piston means comprises a holding element permeable to the blood circulated into the passage and impermeable to the particulate adsorbent.
Claim 10
Dependent Claim 13 words
A device as in claim 8, wherein the holding element comprises a filter.
Claim 11
Dependent Claim 56 words
A device as in claim 8, and further comprising three way valve means connected to the means for connecting the housing into the extracoporeal blood circulation for so connecting the housing, for switching the circulation to the housing to at least one of a flushing agent and nutrient broth, and for stopping circuation to the housing.
Claim 12
Dependent Claim 56 words
A device as in claim 3, and further comprising three way valve means connected to the means for connecting the housing into the extracorporeal blood circulation for so connecting the housing, for switching the circulation to the housing to at least one of a flushing agent and nutrient broth, and for stopping circulation to the housing.
Claim 13
Dependent Claim 37 words
A device as in claim 3, wherein the passage terminates in the piston means, and wherein the piston means comprises a holding element permeable to the blood circulated into the passage and impermeable to the particulate adsorbent.
Claim 14
Dependent Claim 48 words
A device as in claim 12, wherein the piston means tapers toward the piston rod, and further comprising an O-ring so placed on the taper as to slip off irreversibly when the piston means is moved into the housing, whereby to indicate that the device has been used.
Claim 15
Dependent Claim 13 words
A device as in claim 12, wherein the holding element comprises a filter.
Claim 16
Dependent Claim 56 words
A device as in claim 12, and further comprising three way valve means connected to the means for connecting the housing into the extracorporeal blood circulation for so connecting the housing, for switching the circulation to the housing to at least one of a flushing agent and nutrient broth, and for stopping circulation to the housing.
Claim 17
Dependent Claim 56 words
A device as in claim 1, and further comprising three way valve means connected to the means for connecting the housing into the extracorporeal blood circulation for so connecting the housing, for switching the circulation to the housing to at least one of a flushing agent and nutrient broth, and for stopping circulation to the housing.

References Cited (Backward Citations)

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1988-11-18 1989-05-20 1989-11-19 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1992-11-18 1993-05-20 1993-11-19 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1996-11-18 1997-05-20 1997-11-19 $7700.00 Window Closed / Lapsed

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