US4542147A
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Perfluoro-1-azatricyclic amine compound
Assignee: Tanabe Pharma Corp
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Filing: 1983-06-17
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Granted: 1985-09-17
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Expires: 2003-06-17
Abstract
Abstract A novel compound of the formula, <IMAGE> wherein k is zero or an integer of 1 to 2, j is an integer of from 1 to 3, l and m are each zero or an integer of from 1 to 3, and n is an integer of from 1 to 4, the rings A, B and C being optionally substituted with at least one trifluoromethyl group or tetrafluoroethyl group is prepared by reacting the perhydro compound corresponding thereto with fluorine. The compound is useful as a material capable of carrying oxygen in an aqueous emulsion for lifesaving a patient suffering from massive hemorrhage and for preserving internal organs in transplantation.
Inventors
- 👤 Kazumasa Yokoyama
- 👤 Chikara Fukaya
- 👤 Yoshio Tsuda
- 👤 Taizo Ono
- 👤 Yoshio Arakawa
- 👤 Yoshihisa Inoue
- 👤 Youichiro Naito
- 👤 Tadakazu Suyama
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:39
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K9/0026; C; C07; C07D; C07D453/00; C07D453/02; C07D471/00; C07D471/02; C07D471/08; C07D487/00; C07D487/02; C07D487/08; C25; C25B; C25B3/00; C25B3/01; C25B3/05; C25B3/09; C25B3/11; C25B3/20; C25B3/27; C25B3/28
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
26 words
A perfluoro-1-azatricyclic amine compound of the formula: ##STR115## any carbon of the formula being optionally substituted with at least one trifluoromethyl group or one pentafluoroethyl group.
Claim 2
Dependent Claim
26 words
A perfluoro-1-azatricyclic amine compound of the formula: ##STR115## any carbon of the formula being optionally substituted with at least one trifluoromethyl group or one pentafluoroethyl group.
Claim 3
Dependent Claim
29 words
A composition for use as a blood substitute or infusion fluid which composition is an aqueous emulsion of a compound of the formula given and defined in claim 1.
Claim 4
Dependent Claim
25 words
A composition according to claim 2, which contains from 5 to 50% (W/V) of the compound of the formula given and defined in claim 1.
Claim 5
Dependent Claim
15 words
A composition according to claim 2, which contains, as emulsifier, a nonionic surfactant and/or phospholipid.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-09-16 | 1989-03-18 | 1989-09-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-09-16 | 1993-03-18 | 1993-09-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-09-16 | 1997-03-18 | 1997-09-17 | $7700.00 | Window Closed / Lapsed |