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US4534899A Expired / Lapsed US ⏱️ 0.0 years remaining

Synthetic phospholipid compounds

Assignee: ZONE ENTERPRISES Inc
•
Filing: 1983-03-07
•
Granted: 1985-08-13
•
Expires: 2003-03-07
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Abstract

Abstract Synthetic phospholipid compounds and their method of preparation, which compounds are phosphatidylethanolamine polycarboxyl polyalkylene glycols and are prepared by the reaction of a phosphatidylethanolamine, a polycarboxylic acid, such as succinic or glutaryl anhydride, and a polyalkylene glycol, such as polyethylene glycol.

Inventors

  • 👤 Barry D. Sears

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 06:31
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/10; A61K9/127; A61K47/00; A61K47/06; A61K47/24; A61K9/0012; A61K9/0019; A61K9/1271; C; C07; C07F; C07F9/00; C07F9/02; C07F9/06; C07F9/08; C07F9/09; C07F9/10; C08; C08G; C08G65/00; C08G65/02; C08G65/32; C08G65/329; C08G65/335; C08G65/3356

Claims Analysis

Total Claims: 25
Claim 1
Independent Claim 76 words
A synthetic phospholipid compound having the structural formula: ##STR3## wherein R 1 and R 2 represent hydrogen or organic acyl radicals; R 3 represents a C 2 to C 4 alkylene radical; X represents hydrogen or an alkyl radical; R 4 represents a C 2 to C 10 alkylene radical; R 5 represents an organic linking radical; R 6 represents hydrogen or a lower alkyl radical; and n represents a number of from 0 to 200.
Claim 2
Dependent Claim 76 words
A synthetic phospholipid compound having the structural formula: ##STR3## wherein R 1 and R 2 represent hydrogen or organic acyl radicals; R 3 represents a C 2 to C 4 alkylene radical; X represents hydrogen or an alkyl radical; R 4 represents a C 2 to C 10 alkylene radical; R 5 represents an organic linking radical; R 6 represents hydrogen or a lower alkyl radical; and n represents a number of from 0 to 200.
Claim 3
Dependent Claim 20 words
The phospholipid compound of claim 1 wherein R 1 and R 2 represent C 2 to C 20 fatty-acid radicals.
Claim 4
Dependent Claim 13 words
The phospholipid compound of claim 1 wherein R 5 represents a polymethylene radical.
Claim 5
Dependent Claim 18 words
The phospholipid compound of claim 3 wherein R 5 represents a C 1 to C 4 methylene radical.
Claim 6
Dependent Claim 16 words
The phospholipid compound of claim 1 wherein n represents a number of from 2 to 100.
Claim 7
Dependent Claim 18 words
The phospholipid compound of claim 1 wherein R 1 and R 2 are organic radicals derived from soybeans.
Claim 8
Dependent Claim 13 words
The phospholipid compound of claim 1 wherein R 4 represents an ethylene radical.
Claim 9
Dependent Claim 13 words
The phospholipid compound of claim 1 wherein R 3 represents an ethylene radical.
Claim 10
Dependent Claim 13 words
The phospholipid compound of claim 1 wherein R 6 represents a methyl radical.
Claim 11
Dependent Claim 16 words
The phospholipid compound of claim 1 wherein the molecular weight is from about 150 to 3000.
Claim 12
Dependent Claim 51 words
The synthetic phospholipid compound having the structural formula: ##STR4## wherein R 1 and R 2 represent C 2 to C 20 hydrocarbon organic acyl radicals; X represents hydrogen or a methyl radical; m represents a number of from 1 to 4; and n represents a number of from 0 to 200.
Claim 13
Dependent Claim 51 words
The synthetic phospholipid compound having the structural formula: ##STR4## wherein R 1 and R 2 represent C 2 to C 20 hydrocarbon organic acyl radicals; X represents hydrogen or a methyl radical; m represents a number of from 1 to 4; and n represents a number of from 0 to 200.
Claim 14
Dependent Claim 12 words
The synthetic phospholipid compound which is a phosphatidylethanolamine succinyl polyethylene glycol compound.
Claim 15
Dependent Claim 12 words
The synthetic phospholipid compound which is a phosphatidylethanolamine succinyl polyethylene glycol compound.
Claim 16
Dependent Claim 12 words
The synthetic phospholipid compound which is a phosphatidylethanolamine glutaryl polyethylene glycol compound.
Claim 17
Dependent Claim 12 words
The synthetic phospholipid compound which is a phosphatidylethanolamine glutaryl polyethylene glycol compound.
Claim 18
Dependent Claim 17 words
The synthetic phospholipid compound which is a phosphatidylethanolamine di or tri carboxyl polyethylene or polypropylene glycol compound.
Claim 19
Dependent Claim 17 words
The synthetic phospholipid compound which is a phosphatidylethanolamine di or tri carboxyl polyethylene or polypropylene glycol compound.
Claim 20
Dependent Claim 18 words
The synthetic phospholipid compound of claim 14 wherein the compound is a polyethylene or polypropylene monomethyl ether compound.
Claim 21
Dependent Claim 17 words
The synthetic phospholipid compound of claim 14 wherein the carboxyl is a C 3 -C 6 carboxyl.
Claim 22
Dependent Claim 11 words
The synthetic phospholipid compound soy phosphatidylethanolamine succinyl polyethylene glycol monomethyl ether.
Claim 23
Dependent Claim 11 words
The synthetic phospholipid compound soy phosphatidylethanolamine succinyl polyethylene glycol monomethyl ether.
Claim 24
Dependent Claim 11 words
The synthetic phospholipid compound soy phosphatidylethanolamine glutaryl polyethylene glycol monomethyl ether.
Claim 25
Dependent Claim 11 words
The synthetic phospholipid compound soy phosphatidylethanolamine glutaryl polyethylene glycol monomethyl ether.

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1988-08-12 1989-02-11 1989-08-13 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1992-08-12 1993-02-11 1993-08-13 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1996-08-12 1997-02-11 1997-08-13 $7700.00 Window Closed / Lapsed

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