US4532128A
Expired / Lapsed
US
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Quaternary ammonium group-containing polymers having antimicrobial activity
Assignee: Novartis Corp
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Filing: 1984-09-17
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Granted: 1985-07-30
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Expires: 2004-09-17
Abstract
Abstract Polymeric quaternary ammonium compounds having recurring vinylbenzyl ammonium units are disclosed. The quaternary ammonium units preferably have 2 alkyl substituents of 1 to 4 carbons and 1 alkyl substituent of 4 to 12 carbons. These materials have antimicrobial properties and are particularly useful for preserving ophthalmic solutions.
Inventors
- 👤 Bernard G. Sheldon
- 👤 Robert E. Wingard, Jr.
- 👤 Ned M. Weinshenker
- 👤 Daniel J. Dawson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:49
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/74; A61K31/745; A61K31/785
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
85 words
A method of inhibiting bacterial growth comprising applying to said bacteria an effective bacteria growth inhibiting amount of an antibacterial composition comprising an effective antibacterial concentration of a polymeric quaternary ammonium compound having at least about 10 recurring structural units of the formula: ##STR13## wherein R is a 4 to 12 atom alkyl, X - is a physiologically acceptable halide anion and R' and R" are independently selected from the group of alkyls of from 1 to 4 carbon atoms, in a hygienically acceptable carrier.
Claim 2
Independent Claim
85 words
A method of inhibiting bacterial growth comprising applying to said bacteria an effective bacteria growth inhibiting amount of an antibacterial composition comprising an effective antibacterial concentration of a polymeric quaternary ammonium compound having at least about 10 recurring structural units of the formula: ##STR13## wherein R is a 4 to 12 atom alkyl, X - is a physiologically acceptable halide anion and R' and R" are independently selected from the group of alkyls of from 1 to 4 carbon atoms, in a hygienically acceptable carrier.
Claim 3
Dependent Claim
16 words
The method of claim 1 wherein R' and R" are identical 1 or 2 carbon alkyls.
Claim 4
Dependent Claim
14 words
The method of claim 2 wherein R is an about 8 carbon atom alkyl.
Claim 5
Dependent Claim
16 words
The method of claim 1 wherein R is n-octyl and R' and R" are each methyl.
References Cited (Backward Citations)
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Cited
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-07-29 | 1989-01-28 | 1989-07-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-07-29 | 1993-01-28 | 1993-07-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-07-29 | 1997-01-28 | 1997-07-30 | $7700.00 | Window Closed / Lapsed |