Dose metering plunger devices for use with syringes

Claim 2

A dose metering device for a syringe having a cylinder in which a piston moves to express liquid therefrom, which device comprises an axially-movable plunger which is adapted in use to drive the piston axially in the cylinder for dose expression therefrom, a manually-rotatable operating member, a rotary screw mechanism operatively associated with the plunger, a unidirectional coupling by which the operating member is operatively coupled to the rotary screw mechanism, angular rotation of the operating member in one direction (referred to as the forward direction) being transmitted by the unidirectional coupling to the rotary screw mechanism which is arranged to convert said transmitted rotation into corresponding axial movement of the plunger, whereby in use successive rotary operating strokes of the operating member in the said forward direction are converted into successive axial movement steps of the plunger to express successive doses from the syringe whose volumes correspond to the angular extents of the respective operating strokes of the operating member, and stop means arranged to limit each of the said operating strokes of the operating member at the same predetermined angular finishing point, the unidirectional coupling permitting the manual angular retraction of the operating member independently of the plunger after each said operating stroke from its finishing point predetermined by the stop means to a selected angular position constituting a variable starting point for the next operating stroke, and scale means arranged to indicate selectable angular positions of a plurality of said starting points, whereby the volume of each dose to be expressed is variably preset in use by selection of the angular position, as indicated by the scale means, of the starting point of the respective operating stroke of the operating member.

Claim 3

A device as claimed in claim 1, in which the scale means comprises an arcuate scale of indicia and a cooperating pointer, by which the angular extent of each operating stroke from its selected starting point to the finishing point determined by the stop means can be measured directly on the scale, from which measurement the volume of the corresponding dose is ascertainable, the operating member being rotatable into a position in which the pointer indicates the selected starting point on the scale.

Claim 4

A device as claimed in claim 1 or claim 2, in which the scale means is calibrated in units of dose volume.

Claim 5

A device as claimed in claim 1 or claim 2, in which the screw mechanism comprises an external helical screwthread formed coaxially on the plunger and a cooperating internal helical screwthread formed in a part which in use is fixed to the cylinder, the plunger being rotatable relative to the cylinder.

Claim 6

A device as claimed in claim 4, in which the operating member is coupled coaxially to the plunger through the said unidirectional coupling and screw mechanism.

Claim 7

A device as claimed in claim 5, in which the operating member is coupled coaxially through the unidirectional coupling to a rotary driving member keyed to the threaded plunger for coaxial rotation therewith but axially slidable relative thereto.

Claim 8

A device as claimed in claim 6, in which the threaded plunger comprises a tubular member having an axial bore, and the rotary driving member is an elongate member extending slidably within said bore and keyed to the plunger for rotation therewith.

Claim 9

A device as claimed in claim 1 or claim 2, in which the unidirectional coupling is a ratchet and pawl mechanism.

Claim 10

A device as claimed in claim 7, in which the unidirectional coupling is a ratchet and pawl mechanism whereof the ratchet comprises a toothed wheel secured coaxially to the rotary driving member and the cooperating pawl is carried by the operating member.

Claim 11

A device as claimed in claim 1 or claim 2, in which the stop means comprises a stop member carried by a part of the device which in use is atached to the cylinder of a syringe, and a cooperating abutment on the operating member which is adapted to engage the stop at the end of each operating stroke.

Claim 12

A device as claimed in claim 10 in which the stop member is a fixed stop.

Claim 13

A device as claimed in claim 11 in which the stop member is detachably mounted on the said part and in which the abutment is formed in a pointer constituting a part of the scale means and carried by the operating member.

Claim 14

A device as claimed in claim 1 or claim 2, in which the stop means includes a fixed stop.

Claim 15

A device as claimed in claim 7, in which the said tubular member is adapted to be detachably secured to the cylinder of a syringe, and carries a stop member.

Claim 16

A device as claimed in claim 14, in which the stop member forms part of a releasable connection between said tubular member and the cylinder.

Claim 17

A device as claimed in claim 1 or claim 2, in combination with a syringe having a cylinder to which said device is attached and a piston arranged to be acted on by the plunger of said device for dose expression.

Claim 18

A syringe including a cylinder and a piston movable axially in said cylinder to express liquid therefrom, an axially-movable plunger arranged and adapted to drive the piston for expression of a dose of liquid, a manually-rotatable operating member, a rotary screw mechanism operatively associated with the plunger, a unidirectional coupling by which the operating member is operatively coupled to the rotary screw mechanism, angular rotation of the operating member in one direction (referred to as the forward direction) being transmitted by the unidirectional coupling to the rotary screw mechanism which is arranged to convert said transmitted rotation into corresponding axial movement of the plunger whereby in use successive rotary operating strokes of the operating member in the said forward direction are converted into successive axial movement steps of the plunger to express successive doses from the syringe whose volumes correspond to the angular extents of the respective operating strokes of the operating member, and stop means arranged to limit each of the said operating strokes of the operating member at the same predetermined angular finishing point, the unidirectional coupling permitting the manual angular retraction of the operating member independently of the plunger after each said operating stroke from its finishing point predetermined by the stop means to a selected angular position constituting a variable starting point for the next operating stroke, and scale means arranged to indicate selectable angular positions of a plurality of said starting points, whereby the volume of each dose to be expressed is variably preset in use by selection of the angular position, as indicated by the scale means, of the starting point of the respective operating stroke of the operating member.

Claim 19

A syringe including a cylinder and a piston movable axially in said cylinder to express liquid therefrom, an axially-movable plunger arranged and adapted to drive the piston for expression of a dose of liquid, a manually-rotatable operating member, a rotary screw mechanism operatively associated with the plunger, a unidirectional coupling by which the operating member is operatively coupled to the rotary screw mechanism, angular rotation of the operating member in one direction (referred to as the forward direction) being transmitted by the unidirectional coupling to the rotary screw mechanism which is arranged to convert said transmitted rotation into corresponding axial movement of the plunger whereby in use successive rotary operating strokes of the operating member in the said forward direction are converted into successive axial movement steps of the plunger to express successive doses from the syringe whose volumes correspond to the angular extents of the respective operating strokes of the operating member, and stop means arranged to limit each of the said operating strokes of the operating member at the same predetermined angular finishing point, the unidirectional coupling permitting the manual angular retraction of the operating member independently of the plunger after each said operating stroke from its finishing point predetermined by the stop means to a selected angular position constituting a variable starting point for the next operating stroke, and scale means arranged to indicate selectable angular positions of a plurality of said starting points, whereby the volume of each dose to be expressed is variably preset in use by selection of the angular position, as indicated by the scale means, of the starting point of the respective operating stroke of the operating member.

Claim 20

A syringe as claimed in claim 17, in which the scale means comprises an arcuate scale of indicia and a cooperating pointer by which the angular extent of each operating stroke from its selected starting point to the finishing point determined by the stop can be measured directly on the scale, from which measurement the volume of the corresponding dose is ascertainable, the operating member being rotatable into a position in which the pointer indicates the selected starting point on the scale.

Claim 21

A syringe as claimed in claim 18, in which the scale is calibrated in units of dose volume.

Claim 22

A syringe as claimed in any one of claims 17 through 19, in which the said screw mechanism comprises an external helical screwthread formed coaxially on the plunger and a cooperating internal helical screwthread formed in the cylinder, the plunger being rotatable in the cylinder by said operating member acting through the unidirectional coupling.

Claim 23

A syringe as claimed in claim 20, in which the operating member is coupled coaxially to the plunger through the said unidirectional coupling and screw mechanism.

Claim 24

A syringe as claimed in claim 21, which includes a rotary driving member to which the operating member is coaxially coupled by the unidirectional coupling, the rotary driving member being keyed to the threaded plunger for coaxial rotation therewith but being axially slidable relative thereto.

Claim 25

A syringe as claimed in claim 22, in which the threaded plunger comprises a tubular member having an axial bore, and in which the rotary driving member is an elongate member extending slidably within said bore and keyed to the plunger for rotation therewith.

Claim 26

A syringe as claimed in claim 23, in which said unidirectional coupling comprises a ratchet and pawl mechanism whereof the ratchet comprises a toothed wheel secured coaxially to the rotary driving member and the cooperating pawl is carried by the operating member.

Claim 27

A syringe as claimed in any one of claims 17 through 19, wherein the stop means comprises a stop member carried by the cylinder of the syringe, and a cooperating abutment on the operating member adapted and arranged to engage the stop member at the end of each operating stroke.

Claim 28

A syringe as claimed in claim 25, wherein the stop member is a fixed stop.

Claim 29

A syringe as claimed in any one of claims 17 through 19, in which the unidirectional coupling comprises a ratchet and pawl mechanism.

Claim 30

A syringe as claimed in any one of claims 17 through 19, in which the cylinder is adapted to receive and directly contain a quantity of the dose of liquid sealed in the cylinder by the piston which is a close sliding fit in the piston.

Claim 31

A syringe as claimed in any one of claims 17 through 19, in which the cylinder is adapted to hold an ampoule prefilled with a quantity of the dose liquid, the piston being arranged and adapted to express liquid from a said ampoule in the cylinder when the piston is advanced along the cylinder during an operating stroke of the operating member.

Claim 32

A syringe as claimed in claim 29, in which a piston of the syringe is contained in the prefilled ampoule and seals said quantity of dose liquid therein, the piston being a close sliding fit within the interior of the ampoule.

Claim 33

A syringe as claimed in claim 29, including a tubular needle mounted in the cylinder and arranged to pierce the wall of the ampoule to allow dose liquid to be expressed therefrom through the needle during an operating stroke of the operating member.

Claim 34

A syringe as claimed in claim 29, in which the operating member comprises a sleeve rotatably mounted on the exterior of the cylinder and slidable thereon between a first and a second longitudinal position thereon, and in which the stop means includes a stop mounted on the cylinder and a cooperating abutment on the sleeve, the abutment engaging with the stop to limit the rotation of the sleeve when the sleeve is in the said first longitudinal position, but the abutment being movable clear of the stop by sliding movement of the sleeve into the said second longitudinal position wherein the stop no longer hinders the free rotation of the sleeve on the cylinder.

Claim 35

A syringe as claimed in claim 32, in which the sleeve is arranged to be held in its said first longitudinal position by an ampoule inserted into the cylinder, and to be free to move into its said second longitudinal position when the ampoule is removed from the cylinder.

Claim 36

A syringe comprising a cylinder and a piston movable axially in the cylinder for the expression of dose liquid therefrom, an internal helical screwthread formed on the surface of the cylinder, an elongate plunger in the cylinder arranged to act on the piston, an external helical screwthread formed on the plunger, said internal and external screwthreads being in threaded relationship whereby a rotation of the plunger about its longitudinal axis is converted into a corresponding axial movement of the plunger and piston for expressing a dose, a rotary driving member keyed to the plunger for coaxial rotation therewith, the plunger being longitudinal slidable relative to the rotary driving member, a manual operating member rotatably mounted coaxially on the cylinder, a ratchet and pawl mechanism acting between the operating member and the rotary driving member whereby an angular rotation of the operating member in a first angular direction is transmitted to the rotary driving member and thence to the plunger to cause the plunger to advance the piston a corresponding axial distance so as to express a dose whose volume corresponds to the angle through which the operating member is rotated, stop means adapted and arranged to limit the rotation of the operating member in the said first angular direction at a predetermined finishing position, the ratchet and pawl mechanism permitting the manual rotation of the operating member in the direction opposite to the said first angular direction from the predetermined finishing point to a variably-selected starting position for a subsequent dose expression, and scale means arranged to indicate a plurality of selectable starting positions, whereby the volume of each dose to be expressed from the syringe is variably preset in use by selection of the angular starting point, indicated on the scale means, to which the operating member is rotated prior to its rotation towards the finishing point for the expression of that dose.

Claim 37

A syringe comprising a cylinder and a piston movable axially in the cylinder for the expression of dose liquid therefrom, an internal helical screwthread formed on the surface of the cylinder, an elongate plunger in the cylinder arranged to act on the piston, an external helical screwthread formed on the plunger, said internal and external screwthreads being in threaded relationship whereby a rotation of the plunger about its longitudinal axis is converted into a corresponding axial movement of the plunger and piston for expressing a dose, a rotary driving member keyed to the plunger for coaxial rotation therewith, the plunger being longitudinal slidable relative to the rotary driving member, a manual operating member rotatably mounted coaxially on the cylinder, a ratchet and pawl mechanism acting between the operating member and the rotary driving member whereby an angular rotation of the operating member in a first angular direction is transmitted to the rotary driving member and thence to the plunger to cause the plunger to advance the piston a corresponding axial distance so as to express a dose whose volume corresponds to the angle through which the operating member is rotated, stop means adapted and arranged to limit the rotation of the operating member in the said first angular direction at a predetermined finishing position, the ratchet and pawl mechanism permitting the manual rotation of the operating member in the direction opposite to the said first angular direction from the predetermined finishing point to a variably-selected starting position for a subsequent dose expression, and scale means arranged to indicate a plurality of selectable starting positions, whereby the volume of each dose to be expressed from the syringe is variably preset in use by selection of the angular starting point, indicated on the scale means, to which the operating member is rotated prior to its rotation towards the finishing point for the expression of that dose.

Claim 38

A syringe as claimed in claim 34, in which the scale means is calibrated in units of dose volume whereby the volume of each dose to be expressed is readable directly by reading the position of the corresponding said starting point selected on the scale.

Claim 39

A syringe as claimed in claim 34 or claim 35, in which the scale means comprises an arcuate scale of indicia and a cooperating pointer, one on the sleeve and the other on the cylinder.

Claim 40

A syringe as claimed in claim 34 or 35, in which the operating member comprises a sleeve rotatably mounted on the exterior of the cylinder and slidable thereon between a first and a second longitudinal position, and in which the stop means includes a stop mounted on the cylinder and a cooperating abutment on the sleeve, the abutment engaging with the stop means to limit the rotation of the sleeve when the sleeve is in the said first longitudinal position, but the abutment being movable clear of the stop by sliding movement of the sleeve into the said second longitudinal position wherein the stop no longer hinders the free rotation of the sleeve on the cylinder.

Claim 41

A syringe as claimed in claim 37, in which the cylinder is adapted to hold an ampoule prefilled with a quantity of dose liquid sealed in the ampoule, and in which the sleeve is arranged to be held in its said first longitudinal position by an ampoule inserted into the cylinder and to be free to move into its second longitudinal member when the ampoule is removed from the cylinder.

Claim 42

A syringe as claimed in claim 38, including a detent member slidably mounted in the cylinder and having a portion extending through a longitudinal aperture slot formed in the wall of the cylinder, the detent member being arranged to engage at one end outside the cylinder with the sleeve and to be engaged at its other end within the interior of the sleeve by an ampoule inserted into the cylinder, the ampoule when fully inserted causing the detent member to hold the sleeve in its said first longitudinal position, and the detent being slidable when the ampoule is removed to allow the sleeve to be moved into its said second longitudinal position.

Claim 43

A syringe comprising a cylinder, a piston movable axially in the cylinder for the expression of dose liquid therefrom, an internal helical screwthread formed in the cylinder, an elongate plunger in the cylinder arranged to act on the piston, an external helical screwthread formed on the plunger, said internal and external screwthread being in threaded relationship whereby a rotation of the plunger about its longitudinal axis is converted into a corresponding axial movement of the plunger and piston for expressing a dose, a manual operating sleeve rotatably mounted coaxially on the cylinder, a ratchet and pinion mechanism arranged to transmit a rotation of the operating sleeve in a first angular direction to the threaded plunger to cause the plunger to advance the piston a corresponding axial distance so as to express a dose whose volume corresponds to the angle through which the operating sleeve is rotated, stop means adapted and arranged to limit the rotation of the operating sleeve in the said first angular direction at a predetermined finishing point, the ratchet and pawl mechanism permitting the manual rotation of the operating sleeve in the said first angular direction from the predetermined finishing point to a variably-selected starting point for a subsequent dose expression, and scale means arranged to indicate a plurality of selectable starting points, whereby the volume of each dose to be expressed from the syringe is variably preset in use by selection of the angular starting point, indicated on the scale means, to which the operating sleeve is rotated prior to its rotation towards the finishing point for the expression of that dose.

Claim 44

A syringe comprising a cylinder, a piston movable axially in the cylinder for the expression of dose liquid therefrom, an internal helical screwthread formed in the cylinder, an elongate plunger in the cylinder arranged to act on the piston, an external helical screwthread formed on the plunger, said internal and external screwthread being in threaded relationship whereby a rotation of the plunger about its longitudinal axis is converted into a corresponding axial movement of the plunger and piston for expressing a dose, a manual operating sleeve rotatably mounted coaxially on the cylinder, a ratchet and pinion mechanism arranged to transmit a rotation of the operating sleeve in a first angular direction to the threaded plunger to cause the plunger to advance the piston a corresponding axial distance so as to express a dose whose volume corresponds to the angle through which the operating sleeve is rotated, stop means adapted and arranged to limit the rotation of the operating sleeve in the said first angular direction at a predetermined finishing point, the ratchet and pawl mechanism permitting the manual rotation of the operating sleeve in the said first angular direction from the predetermined finishing point to a variably-selected starting point for a subsequent dose expression, and scale means arranged to indicate a plurality of selectable starting points, whereby the volume of each dose to be expressed from the syringe is variably preset in use by selection of the angular starting point, indicated on the scale means, to which the operating sleeve is rotated prior to its rotation towards the finishing point for the expression of that dose.

Claim 45

A syringe as claimed in claim 40, in which the scale means is calibrated in units of dose volume whereby the volume of each dose to be expressed is readable directly by reading the position of the corresponding said starting point selected on the scale.

Claim 46

A syringe as claimed in claim 40 or claim 41, in which the ratchet and pawl mechanism comprises a toothed ratchet formation formed circumferentially around and in the internal wall surface of the sleeve, and a cooperating pawl carried by the plunger.

Claim 47

A syringe as claimed in claim 40 or claim 41, in which the operating sleeve is longitudinally slidably on the cylinder, and in which the stop means comprises a movable stop member carried by the cylinder and held in an operative position in which it is entered into a circumferential groove formed in and around the inner surfaces of the wall of the sleeve so as to retain the sleeve in an operative longitudinal position on the cylinder, in which operative longitudinal position the sleeve is rotatable for dose expression, the sleeve having an abutment arranged to engage the stop member and limit the rotation of the sleeve in the said predetermined finishing position when the stop member is entered in the groove, and in which the stop member is retractable from the groove to allow the sleeve to be slid longitudinally off the cylinder.

Claim 48

A syringe as claimed in claim 43, in which the cylinder is adapted to hold an ampoule prefilled with a quantity of dose liquid sealed in the ampoule by a piston of the syringe which is a sliding fit in the interior of the ampoule, and in which the movable stop is resiliently biassed away from its operative position entered in the groove, but is arranged to be held in said operative position by an ampoule when inserted into the cylinder.