US4485029A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Disinfecting method and compositions
Assignee: 3M Co
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Filing: 1984-03-19
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Granted: 1984-11-27
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Expires: 2004-03-19
Abstract
Abstract A composition is disclosed which includes the use of glyceryl monolaurate in combination with one or more other anti-microbial agents and, optionally an organic surfactant as a cleaning, disinfecting and preserving system which must be non-irritating and non-allergenic to body tissues. The composition is effective against a variety of microorganisms within a reasonable period of time, at concentrations that, if desired, can result in a visually clear solution. It is useful in a solution for cleaning, disinfecting and preserving contact lenses.
Inventors
- 👤 Kenneth H. Kato
- 👤 Arlene J. Mencke
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:10
CPC Classifications
A; A61; A61L; A61L12/00; A61L12/08; A61L12/14; A01; A01N; A01N37/00; A01N37/12; A01N37/36; A01N37/38; A01N37/40
Claims Analysis
Total Claims: 24
Claim 1
Independent Claim
73 words
An aqueous ophthalmic composition, which is non-irritating to the eyes, for cleaning, disinfecting or preserving contact lenses comprising (a) water; (b) an effective amount of up to 0.1% by weight of a first anti-microbial agent consisting essentially of a polyol ester having a formula selected from ##STR2## where R is the residue of lauric acid; and (c) an effective amount of a second anti-microbial agent comprising one or more esters of para-hydroxybenzoic acid.
Claim 2
Dependent Claim
73 words
An aqueous ophthalmic composition, which is non-irritating to the eyes, for cleaning, disinfecting or preserving contact lenses comprising (a) water; (b) an effective amount of up to 0.1% by weight of a first anti-microbial agent consisting essentially of a polyol ester having a formula selected from ##STR2## where R is the residue of lauric acid; and (c) an effective amount of a second anti-microbial agent comprising one or more esters of para-hydroxybenzoic acid.
Claim 3
Dependent Claim
7 words
An aqueous solution according to claim 1.
Claim 4
Dependent Claim
10 words
A buffered, sterile, and isotonic composition according to claim 1.
Claim 5
Dependent Claim
10 words
An optically clear composition according to claim 2 or 3.
Claim 6
Dependent Claim
28 words
A composition according to claim 1 wherein said second anti-microbial agent comprises a mixture of the methyl ester of para-hydroxybenzoid acid and the propyl ester of para-hydroxybenzoid acid.
Claim 7
Dependent Claim
45 words
A composition according to claim 5 wherein said mixture comprises from about 0.005 to 0.3% by weight of said composition of the methyl ester of para-hydroxybenzoic acid and from about 0.005 to 0.1% by weight of said composition of the propyl ester of para-hydroxybenzoic acid.
Claim 8
Dependent Claim
11 words
A composition according to claim 1 further comprising an organic surfactant.
Claim 9
Dependent Claim
6 words
A solution according to claim 7.
Claim 10
Dependent Claim
10 words
A buffered, sterile and isotonic composition according to claim 7.
Claim 11
Dependent Claim
10 words
An optically clear composition according to claim 8 or 9.
Claim 12
Dependent Claim
28 words
A composition according to claim 7 wherein said second anti-microbial agent comprises a mixture of the methyl ester of para-hydroxybenzoic acid and the propyl ester of para-hydroxybenzoid acid.
Claim 13
Dependent Claim
45 words
A composition according to claim 11 wherein said mixture comprises from about 0.005 to 0.3% by weight of said composition of the methyl ester of para-hydroxybenzoic acid and from about 0.005 to 0.1% by weight of said composition of the propyl ester of para-hydroxybenzoic acid.
Claim 14
Dependent Claim
11 words
A composition according to claim 7 wherein said surfactant is anionic.
Claim 15
Dependent Claim
24 words
A composition according to claim 7 wherein said surfactant is present in an amount effective to maximize the solubility of said first anti-microbial agent.
Claim 16
Dependent Claim
24 words
A composition according to claim 7 wherein said surfactant is present in an amount from about 0.005 to 0.15% by weight of said composition.
Claim 17
Dependent Claim
12 words
A composition according to claim 1 or 7 further comprising ethylenediaminetetraacetic acid.
Claim 18
Dependent Claim
34 words
A method of cleaning contact lenses comprising rubbing said lenses with the aqueous composition of claim 1 or 7 and rinsing said lenses for a time sufficient to remove foreign material from said lenses.
Claim 19
Dependent Claim
29 words
A method of disinfecting contact lenses comprising contacting said lenses with said aqueous composition of claim 1 or 7 for a time sufficient to kill microorganisms on said lenses.
Claim 20
Dependent Claim
30 words
A method of preserving contact lenses comprising contacting said lenses with said aqueous composition of claim 1 or 7 for a time sufficient to inhibit microorganism growth on said lenses.
Claim 21
Dependent Claim
18 words
A composition according to claim 1 wherein the pH of said composition is from about 4 to 10.
Claim 22
Dependent Claim
15 words
A composition according to claim 20 wherein said pH is from about 5 to 8.
Claim 23
Dependent Claim
91 words
An aqueous ophthalmic composition, which is non-irritating to the eyes, for cleaning, disinfecting or preserving contact lenses comprising (a) at least 99% water; (b) 0.0001 to 0.1% by weight of a first anti-microbial agent consisting essentially of a polyol ester having a formula selected from ##STR3## where R is the residue of lauric acid. (c) 0.02 to 0.2% of a second antimicrobial agent comprising one or more esters of para-hydroxybenzoic acid; and (d) 0 to 0.15% of an organic surfactant, said composition having a pH of from about 5 to 8.
Claim 24
Dependent Claim
91 words
An aqueous ophthalmic composition, which is non-irritating to the eyes, for cleaning, disinfecting or preserving contact lenses comprising (a) at least 99% water; (b) 0.0001 to 0.1% by weight of a first anti-microbial agent consisting essentially of a polyol ester having a formula selected from ##STR3## where R is the residue of lauric acid. (c) 0.02 to 0.2% of a second antimicrobial agent comprising one or more esters of para-hydroxybenzoic acid; and (d) 0 to 0.15% of an organic surfactant, said composition having a pH of from about 5 to 8.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-11-27 | 1988-05-28 | 1988-11-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-11-27 | 1992-05-28 | 1992-11-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-11-27 | 1996-05-28 | 1996-11-27 | $7700.00 | Window Closed / Lapsed |