US4481827A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Blood fractionation apparatus having collection rate display system
Assignee: Baxter International Inc
•
Filing: 1981-12-15
•
Granted: 1984-11-13
•
Expires: 2001-12-15
Abstract
Abstract An apparatus for separating and collecting plasma from whole blood includes a collection rate monitoring system which provides a digital display of the rate of plasma collection per minute. A transducer circuit within the system develops an electrical signal frequency-dependent on the weight of the collected plasma. The frequency of this signal over a present measurement interval is periodically compared with the frequency of the signal over a preceding measurement interval to develop a signal indicative of the volume of plasma collected during the interval. This signal is combined in a shift register with signals developed over a plurality of immediately preceding measurement intervals, which, taken with the present interval, comprise a one minute period, to develop at the end of each interval an output signal indicative of the total units of plasma collected over the previous minute. A display counter responsive to each output of the shift register produces a digital display of collected volume units per minute. In the illustrated embodiment, each measurement interval is one second, and the present increment and fifty-nine immediately preceding increments are combined to obtain a readout in units per minute.
Inventors
- 👤 Arnold C. Bilstad
- 👤 John T. Foley
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 08:09
CPC Classifications
G; G01; G01G; G01G17/00; G01G17/04; G01G17/06; A; A61; A61M; A61M1/00; A61M1/34; A61M1/3496; B; B01; B01D; B01D61/00; B01D61/14; B01D61/147; B01D63/00; B01D63/02; G01F; G01F1/00; G01F1/76; A61M2205/00; A61M2205/33; A61M2205/3379; A61M2205/3393; A61M2209/00; A61M2209/08; A61M2209/082
Claims Analysis
Total Claims: 31
Claim 1
Independent Claim
147 words
In a fluid collection apparatus for collecting fluid in a collection container, a collection rate monitoring system comprising, in combination: weight responsive means including an electrical transducer in supporting relationship to the collection container for providing an output signal indicative of the weight of the collection chamber and the collected fluid contained therein; comparison means for repetitively comparing said transducer output signal over a measurement interval with said output signal over a preceding measurement interval to develop a collection signal indicative of the volume of fluid collected during the interval; accumulator means comprising a counter for developing the sum of said collection signals over a predetermined number of the most recent of said collection intervals corresponding to a unit of time; and rate derivation means for periodically developing from the sum of said incremental collection signals in said counter an output signal indicative of the collection rate.
Claim 2
Dependent Claim
147 words
In a fluid collection apparatus for collecting fluid in a collection container, a collection rate monitoring system comprising, in combination: weight responsive means including an electrical transducer in supporting relationship to the collection container for providing an output signal indicative of the weight of the collection chamber and the collected fluid contained therein; comparison means for repetitively comparing said transducer output signal over a measurement interval with said output signal over a preceding measurement interval to develop a collection signal indicative of the volume of fluid collected during the interval; accumulator means comprising a counter for developing the sum of said collection signals over a predetermined number of the most recent of said collection intervals corresponding to a unit of time; and rate derivation means for periodically developing from the sum of said incremental collection signals in said counter an output signal indicative of the collection rate.
Claim 3
Dependent Claim
18 words
A fluid collection rate monitoring system as defined in claim 1 wherein said counter comprises a shift register.
Claim 4
Dependent Claim
39 words
A fluid collection rate monitoring system as defined in claim 2 wherein said rate derivation circuit includes a display counter, and wherein data transfer means are provided for periodically transferring data in said shift register to said display counter.
Claim 5
Dependent Claim
37 words
A fluid rate monitoring system as defined in claim 1 wherein said measurement intervals each comprise one second, said unit of time comprises one minute, and wherein sixty of said measurement intervals are summed by said counter.
Claim 6
Dependent Claim
26 words
A fluid collection rate monitoring system as defined in claim 1 wherein said rate derivation means develop said rate output after each of said measurement intervals.
Claim 7
Dependent Claim
158 words
In a fluid collection apparatus for collecting fluid in a collection chamber, a collection rate monitoring system comprising, in combination: weight responsive means including an electrical transducer in supporting relationship to the collection container for providing an output signal indicative of the weight of the collection container and the collected fluid contained therein; comparison means for repetitively comparing said transducer output signal over a measurement interval with said output signal over a preceding measurement interval to develop collection signals each indicative of an incremental volume of fluid collected during the interval; means comprising a shift register for summing said incremental collection signals over a predetermined number of the most recent preceding measurement intervals corresponding to a unit of time; and output circuit means comprising a counter for receiving the count stored in said shift register following each measurement interval, and for providing from said count an output indicative of the collection rate of fluid in the collection container.
Claim 8
Dependent Claim
158 words
In a fluid collection apparatus for collecting fluid in a collection chamber, a collection rate monitoring system comprising, in combination: weight responsive means including an electrical transducer in supporting relationship to the collection container for providing an output signal indicative of the weight of the collection container and the collected fluid contained therein; comparison means for repetitively comparing said transducer output signal over a measurement interval with said output signal over a preceding measurement interval to develop collection signals each indicative of an incremental volume of fluid collected during the interval; means comprising a shift register for summing said incremental collection signals over a predetermined number of the most recent preceding measurement intervals corresponding to a unit of time; and output circuit means comprising a counter for receiving the count stored in said shift register following each measurement interval, and for providing from said count an output indicative of the collection rate of fluid in the collection container.
Claim 9
Dependent Claim
29 words
A fluid collection rate monitoring system as defined in claim 6 including transfer circuit means for serially transferring said collection data in said shift register to said display counter.
Claim 10
Dependent Claim
35 words
A fluid collection rate monitoring system as defined in claim 6 wherein said counter comprises a display counter, and said output circuit includes a digital display device coupled to the output of said display counter.
Claim 11
Dependent Claim
170 words
In a blood fractionation apparatus for separating and collecting a blood fraction from whole blood, and of the type utilizing a disposable flow system having a collection container for the collected component, a collection rate monitoring system comprising, in combination: weight responsive means including an electrical transducer in supporting relationship to the collection container for providing an output signal indicative of the weight of the collection container and the collected blood fraction contained therein; comparison means for repetitively comprising said transducer output signal over a measurement interval with said output signal over an immediately preceding measurement interval to develop a collection signal indicative of the volume of blood fraction collected during the interval; accumulator means comprising a counter for developing the sum of said collection signals over a predetermined number of the most recent of said collection intervals corresponding to a unit of time; and rate derivation means for periodically developing from the sum of said incremental collection signals in said counter an output signal indicative of the collection rate.
Claim 12
Dependent Claim
170 words
In a blood fractionation apparatus for separating and collecting a blood fraction from whole blood, and of the type utilizing a disposable flow system having a collection container for the collected component, a collection rate monitoring system comprising, in combination: weight responsive means including an electrical transducer in supporting relationship to the collection container for providing an output signal indicative of the weight of the collection container and the collected blood fraction contained therein; comparison means for repetitively comprising said transducer output signal over a measurement interval with said output signal over an immediately preceding measurement interval to develop a collection signal indicative of the volume of blood fraction collected during the interval; accumulator means comprising a counter for developing the sum of said collection signals over a predetermined number of the most recent of said collection intervals corresponding to a unit of time; and rate derivation means for periodically developing from the sum of said incremental collection signals in said counter an output signal indicative of the collection rate.
Claim 13
Dependent Claim
18 words
A blood collection rate monitoring system as defined in claim 9 wherein said counter comprises a shift register.
Claim 14
Dependent Claim
39 words
A blood collection rate monitoring system as defined in claim 10 wherein said rate derivation means include a display counter, and wherein data transfer means are provided for periodically transferring data in said shift register to said display counter.
Claim 15
Dependent Claim
38 words
A blood collection rate monitoring system as defined in claim 9 wherein said measurement intervals each comprise one second, said unit of time comprises one minute, and wherein sixty of said measurement intervals are summed by said counter.
Claim 16
Dependent Claim
26 words
A blood collection rate monitoring system as defined in claim 9 wherein said rate derivation means develop said rate output after each of said measurement intervals.
Claim 17
Dependent Claim
192 words
In a blood fractionation apparatus for separating and collecting a blood fraction from whole blood, and of the type utilizing a disposable flow system having a collection container for the collected component, a collection rate display system comprising, in combination: weight responsive means including an electrical transducer in supporting relationship to the collection container for providing an output signal having a frequency related to the weight of the collection container and the collected blood fraction container therein; comparison means for repetitively comparing the frequency of said transducer output signal over a measurement interval with the frequency of said output signal over an immediately preceding measurement interval to develop collection signals each indicative of the incremental volume of blood fraction collected during the interval; means comprising a shift register for summing said collection signals over a predetermined number of the most recent preceding measurement intervals corresponding to a unit of time; and display circuit means comprising a display counter for receiving the count stored in said shift register following each measurement interval, and for providing from said count an output indicative of the collection rate of the blood fraction in the collection container.
Claim 18
Dependent Claim
192 words
In a blood fractionation apparatus for separating and collecting a blood fraction from whole blood, and of the type utilizing a disposable flow system having a collection container for the collected component, a collection rate display system comprising, in combination: weight responsive means including an electrical transducer in supporting relationship to the collection container for providing an output signal having a frequency related to the weight of the collection container and the collected blood fraction container therein; comparison means for repetitively comparing the frequency of said transducer output signal over a measurement interval with the frequency of said output signal over an immediately preceding measurement interval to develop collection signals each indicative of the incremental volume of blood fraction collected during the interval; means comprising a shift register for summing said collection signals over a predetermined number of the most recent preceding measurement intervals corresponding to a unit of time; and display circuit means comprising a display counter for receiving the count stored in said shift register following each measurement interval, and for providing from said count an output indicative of the collection rate of the blood fraction in the collection container.
Claim 19
Dependent Claim
27 words
A blood fractionation apparatus as defined in claim 14 including transfer circuit means for serially transferring said collection data in said shift register to said display counter.
Claim 20
Dependent Claim
117 words
In a fluid collection apparatus for collecting fluid in a collection container, a collection rate monitoring system comprising, in combination: means including an electrical transducer in supporting relationship to the collection container for providing collection signals each indicative of the collection of volume increments of fluid collected in the collection container, said collection signals being derived over a series of discrete measurement intervals; and rate derivation means including a counter for accumulating said collection signals over a unit of time comprising a predetermined number of said measurement intervals, said counter accumulating only the most recent of said intervals, for deriving from said collection signals an output indicative of the rate of fluid collection in the collection container.
Claim 21
Dependent Claim
117 words
In a fluid collection apparatus for collecting fluid in a collection container, a collection rate monitoring system comprising, in combination: means including an electrical transducer in supporting relationship to the collection container for providing collection signals each indicative of the collection of volume increments of fluid collected in the collection container, said collection signals being derived over a series of discrete measurement intervals; and rate derivation means including a counter for accumulating said collection signals over a unit of time comprising a predetermined number of said measurement intervals, said counter accumulating only the most recent of said intervals, for deriving from said collection signals an output indicative of the rate of fluid collection in the collection container.
Claim 22
Dependent Claim
16 words
A collection monitoring system as defined in claim 16 wherein said counter comprises a shift register.
Claim 23
Dependent Claim
38 words
A collection rate monitoring system as defined in claim 17 wherein said rate derivation circuit includes a display counter, and wherein data transfer means are provided for periodically transferring data in said shift register to said display counter.
Claim 24
Dependent Claim
37 words
A collection rate monitoring system as defined in claim 16 wherein said measurement intervals each comprise one second, said unit of time comprises one minute, and wherein sixty of said measurement intervals are summed by said counter.
Claim 25
Dependent Claim
24 words
A collection rate monitoring system as defined in claim 16 wherein said rate derivation means develop said output after each of said measurement intervals.
Claim 26
Dependent Claim
141 words
In a blood fractionation apparaus for separating and collecting a blood fraction from whole blood, and of the type utilizing a disposable flow system having a collection container for the collected component, a collection rate display system comprising, in combination: means including an electrical transducer in supporting relationship to the collection chamber for providing collection signals each indicative of the collection of volume increments of fluid collected in the collection container, said collection signals being derived over a series of discrete measurement intervals; and rate derivation means including a counter for accumulating said collection signals over a unit of time comprising a predetermined number of said measurement intervals, said counter accumulating only the most recent of said intervals, for deriving from said collection signals an output signal indicative of the rate of collection of the collected fraction in the collection container.
Claim 27
Dependent Claim
141 words
In a blood fractionation apparaus for separating and collecting a blood fraction from whole blood, and of the type utilizing a disposable flow system having a collection container for the collected component, a collection rate display system comprising, in combination: means including an electrical transducer in supporting relationship to the collection chamber for providing collection signals each indicative of the collection of volume increments of fluid collected in the collection container, said collection signals being derived over a series of discrete measurement intervals; and rate derivation means including a counter for accumulating said collection signals over a unit of time comprising a predetermined number of said measurement intervals, said counter accumulating only the most recent of said intervals, for deriving from said collection signals an output signal indicative of the rate of collection of the collected fraction in the collection container.
Claim 28
Dependent Claim
16 words
A blood fractionation system as defined in claim 21 wherein said counter comprises a shift register.
Claim 29
Dependent Claim
37 words
A blood fractionation system as defined in claim 22 wherein said rate derivation means include a display counter, and wherein data transfer means are provided for periodically transferring data in said shift register to said display counter.
Claim 30
Dependent Claim
36 words
A blood fractionation apparatus as defined in claim 21 wherein said measurement intervals each comprise one second, said unit of time comprises one minute, and wherein sixty of said measurement intervals are summed by said counter.
Claim 31
Dependent Claim
24 words
A blood fractionation apparatus as defined in claim 22 wherein said rate derivation means develop said rate output after each of said measurement intervals.
References Cited (Backward Citations)
US3375357A
Cited
US3439524A
Cited
US3459182A
Cited
US3655123A
Cited
US3557789A
Cited
US3665169A
Cited
US3684875A
Cited
US3701106A
Cited
US3674097A
Cited
US3789937A
Cited
US3812923A
Cited
US3860802A
Cited
US3855458A
Cited
US3853267A
Cited
US4013194A
Cited
US3916173A
Cited
US4044846A
Cited
US4008405A
Cited
US3960224A
Cited
US4041289A
Cited
US4320855A
Cited
US4144943A
Cited
US4139069A
Cited
US4117898A
Cited
US4151844A
Cited
US4330837A
Cited
US4267837A
Cited
US4294320A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-11-13 | 1988-05-14 | 1988-11-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-11-13 | 1992-05-14 | 1992-11-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-11-13 | 1996-05-14 | 1996-11-13 | $7700.00 | Window Closed / Lapsed |