Patent EP0388576B1 successfully refreshed from Google Patents.
US4478748A
Expired / Lapsed
US
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Bis-esters of alkanediols
Assignee: Pfizer Inc
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Filing: 1982-09-20
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Granted: 1984-10-23
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Expires: 2002-09-20
Abstract
Abstract 6-Acylaminopenicillanoyloxymethyl esters and 1-(6-acylaminopenicillanoyloxy)ethyl esters of 2-beta-acetoxymethyl-2-alpha-methyl-(5R)penam-3-alpha-carboxylic acid 1,1-dioxide are useful as antibacterial agents. The 6-aminopenicillanoyloxymethyl ester, the 1-(6-aminopenicillanoyloxy)ethyl ester and certain other mono-substituted methyl and ethyl esters of 2-beta-acetoxymethyl-2-alpha-methyl-(5R)penam-3-alpha-carboxylic acid 1,1-dioxide are useful intermediates to the aforesaid antibacterial agents.
Inventors
- 👤 Wayne E. Barth
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:54
CPC Classifications
C; C07; C07D; C07D499/00
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
23 words
A compound of the formula ##STR12## and the pharmaceutically-acceptable salts thereof, wherein Q is selected from the group consisting of hydrogen and methyl.
Claim 2
Dependent Claim
23 words
A compound of the formula ##STR12## and the pharmaceutically-acceptable salts thereof, wherein Q is selected from the group consisting of hydrogen and methyl.
Claim 3
Dependent Claim
10 words
The compound according to claim 1, wherein Q is hydrogen.
Claim 4
Dependent Claim
40 words
A compound of the formula ##STR13## wherein Q is selected from the group consisting of hydrogen and methyl; and X is selected from the group consisting of chloro, bromo, iodo, alkylsulfonyloxy having one to four carbon atoms, phenylsulfonyloxy and tolylsulfonyloxy.
Claim 5
Dependent Claim
40 words
A compound of the formula ##STR13## wherein Q is selected from the group consisting of hydrogen and methyl; and X is selected from the group consisting of chloro, bromo, iodo, alkylsulfonyloxy having one to four carbon atoms, phenylsulfonyloxy and tolylsulfonyloxy.
Claim 6
Dependent Claim
10 words
A compound according to claim 3, wherein Q is hydrogen.
Claim 7
Dependent Claim
10 words
The compound according to claim 4, wherein X is chloro.
Claim 8
Dependent Claim
10 words
The compound according to claim 4, wherein X is iodo.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-10-23 | 1988-04-23 | 1988-10-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-10-23 | 1992-04-23 | 1992-10-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-10-23 | 1996-04-23 | 1996-10-23 | $7700.00 | Window Closed / Lapsed |