US4465691A
Expired / Lapsed
US
⏱️ 0.0 years remaining
(3,4';4,5)-Pyrido (3,2-g)-furo coumarins or (3,4-h) pyrido psoralens process of preparation, applications in cosmetology and in therapeutics, and cosmetological and pharmaceutical compositions with them
Assignee: Institut National de la Santé et de la Recherche Médicale
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Filing: 1983-02-24
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Granted: 1984-08-14
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Expires: 2003-02-24
Abstract
Abstract Pyrido (3,4', 4,5) furo (3,2-g) coumarins or pyrido (3,4-h) psoralens having formula I ##STR1## wherein R is a hydrogen radical or a lower alkyl group having from 1 to 4 carbon atoms and R" is a methyl group or a methoxy group. These compounds are photobiologically active and are useful or medicinals and pharmaceutical compositions in association with ultraviolet radiation for treating skin diseases and as cosmetic compositions for skin pigmentation.
Inventors
- 👤 Emile Bisagni
- 👤 Jacqueline Morin
- 👤 Dietrich Averbeck
- 👤 Dubertret Louis
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 15:04
CPC Classifications
C; C07; C07D; C07D213/00; C07D213/02; C07D213/04; C07D213/60; C07D213/72; C07D213/73; A; A61; A61P; A61P17/00; A61P29/00; A61P37/00; A61P37/08; C07D213/62; C07D213/63; C07D213/68; C07D405/00; C07D405/02; C07D405/12; C07D491/00; C07D491/02; C07D491/04; C07D491/12; C07D491/14
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
53 words
Pyrido (3,4-h) psoralens or pyrido (3,4':4,5)furo (3,2-g) courmarins having the formula I ##STR15## wherein R is selected from the group consisting of a hydrogen atom and a lower alkyl group having from 1 to 4 carbon atoms and R' is selected from the group consisting of a methyl group and a methoxy group.
Claim 2
Dependent Claim
53 words
Pyrido (3,4-h) psoralens or pyrido (3,4':4,5)furo (3,2-g) courmarins having the formula I ##STR15## wherein R is selected from the group consisting of a hydrogen atom and a lower alkyl group having from 1 to 4 carbon atoms and R' is selected from the group consisting of a methyl group and a methoxy group.
Claim 3
Dependent Claim
26 words
Pyrido (3,4-h)psoralens or pyrido (3',4':4,5)furo (3,2-g) coumarins of claim 1, wherein R is selected from the group consisting of a methyl group and a hydrogen atom.
Claim 4
Dependent Claim
17 words
Pyrido (3,4-h) psoralens or pyrido (3',4':4,5)furo (3,2-g) coumarins of claim 1, wherein R' is a methyl group.
Claim 5
Dependent Claim
16 words
Pyrido (3,4-h)psoralens or pyrido (3',4':4,5)furo (3,2-g) coumarins of claim 2, wherein R' is a methyl group.
Claim 6
Dependent Claim
22 words
Pyrido (3,4-h) psoralens or pyrido (3',4':4,5)furo(3,2-g) coumarins of claim 1, wherein R is a hydrogen atom and R' is a methyl group.
Claim 7
Dependent Claim
19 words
Pyrido (3,4-h) psoralens or pyrido (3',4':4,5)furo (3,2-g) coumarins of claim 1, wherein R and R' are both methyl groups.
Claim 8
Dependent Claim
83 words
A pharmaceutical composition useful for treating inflammatory dermatoses or for stimulating the pigmentation of the skin, comprising an amount of pyrido (3,4-h) psoralens or pyrido (3',4';4,5) furo (3,2-g) coumarins having the formula ##STR16## wherein R is selected from the group consisting of a hydrogen atom and a lower alkyl group having from 1 to 4 carbon atoms and R' is selected from the group constisting of a methyl group and a methoxy group; and a pharmaceutically acceptable vehicle for local or oral administration.
Claim 9
Dependent Claim
83 words
A pharmaceutical composition useful for treating inflammatory dermatoses or for stimulating the pigmentation of the skin, comprising an amount of pyrido (3,4-h) psoralens or pyrido (3',4';4,5) furo (3,2-g) coumarins having the formula ##STR16## wherein R is selected from the group consisting of a hydrogen atom and a lower alkyl group having from 1 to 4 carbon atoms and R' is selected from the group constisting of a methyl group and a methoxy group; and a pharmaceutically acceptable vehicle for local or oral administration.
Claim 10
Dependent Claim
20 words
The pharmaceutical composition of claim 7, in a form selected from the group consisting of an ointment and a solution.
Claim 11
Dependent Claim
29 words
The pharmaceutical composition of claim 7, wherein said active ingredient is present in a therapeutically effective amount from about 0.1% to about 2% by weight of the pharmaceutical composition.
Claim 12
Dependent Claim
27 words
The pharmaceutical composition of claim 9, wherein said active ingredient is present in an amount from about 0.5% to about 2% by weight of the pharmaceutical composition.
Claim 13
Dependent Claim
42 words
A method of treating inflammatory dermatoses comprising administering to a patient afflicted with said condition an anti-antiflammatory dermatoses effective amount of the compound of claim 1, or a combination thereof, in combination with irradiation with light in the near ultraviolet range (UVA).
Claim 14
Dependent Claim
11 words
The method of claim 11, wherein the inflammatory dermatosis is psoriasis.
References Cited (Backward Citations)
US4260630A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-08-14 | 1988-02-13 | 1988-08-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-08-14 | 1992-02-13 | 1992-08-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-08-14 | 1996-02-13 | 1996-08-14 | $7700.00 | Window Closed / Lapsed |