Patent US1672596A successfully refreshed from Google Patents.
US4440177A
Expired / Lapsed
US
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Respiratory analyzer system
Assignee: Medical Graphics Corp
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Filing: 1981-12-16
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Granted: 1984-04-03
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Expires: 2001-12-16
Abstract
Abstract A system for measuring the ventilatory response of the human respiratory system to increased levels of CO 2 and/or decreased levels of O 2 . Measured concentrations of CO 2 are introduced into an infant's lungs and the inspired and expired air is passed through a pneumotachograph for developing various electrical analog signals relating to flow. Samples of the expired air are delivered to CO 2 and O 2 analyzers. The resulting electrical analog signals produced by these devices represent inspiratory and expiratory flow, and the CO 2 and the O 2 levels in the expired air. They are applied to a waveform analyzer containing an analog to digital converter and a microprocessor system which is programmed to discriminate between normal breathing patterns and irregular patterns. The microprocessor also computes inspiratory and expiratory tidal volume, ventilation (measured in liters per minute), breathing frequency, inspiratory, expiratory and total times of a preceding breath, minimum CO 2 and O 2 , peak CO 2 and O 2 and volume of expired CO 2 and O 2 either on a breath-by-breath basis or over a user selected time interval. The results of these computations are provided in digital form to a digital computer having a graphic display capability. When the ventilation rate is plotted as a function of changes in the inspired CO 2 concentration, the slope of this linear relation is indicative of abnormal ventilatory response, which is deemed helpful in the diagnosis of a number of disease states, e.g., Sudden Infant Death Syndrome.
Inventors
- 👤 Stephen T. Anderson
- 👤 Catherine A. Anderson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 02:40
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/08; A61B5/083
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
206 words
Apparatus for diagnosing possible brain stem disfunction relating to respiration in a patient comprising: (a) means for selectively introducing a plurality of known percentages of a test gas into air being inspired by said patient; (b) means for measuring the inspiratory and expiratory flow of air to and from said patient during time periods related to introduction of each such gas percentage and for developing first electrical signals proportional thereto; (c) means for measuring the percentage concentration of said test gas in the air expired by said patient during time periods related to introduction of each such gas percentage and for producing second electrical signals proportional thereto; (d) analyzer means, including a programmable computing means, connected to receive said first and second electrical signals for integrating said first signals over respective predetermined time intervals and for computing from said second signals the respective alveolar partial pressure of carbon dioxide gas in the expiratory air flow from the lungs of said patient, said analyzer means further including means for determining the change in said integrated first signals relative to said respective alveolar partial pressures; and (e) display means connected to said analyzer means for displaying said relative change, whereby normal and abnormal ventilatory responses may be distinguished.
Claim 2
Dependent Claim
206 words
Apparatus for diagnosing possible brain stem disfunction relating to respiration in a patient comprising: (a) means for selectively introducing a plurality of known percentages of a test gas into air being inspired by said patient; (b) means for measuring the inspiratory and expiratory flow of air to and from said patient during time periods related to introduction of each such gas percentage and for developing first electrical signals proportional thereto; (c) means for measuring the percentage concentration of said test gas in the air expired by said patient during time periods related to introduction of each such gas percentage and for producing second electrical signals proportional thereto; (d) analyzer means, including a programmable computing means, connected to receive said first and second electrical signals for integrating said first signals over respective predetermined time intervals and for computing from said second signals the respective alveolar partial pressure of carbon dioxide gas in the expiratory air flow from the lungs of said patient, said analyzer means further including means for determining the change in said integrated first signals relative to said respective alveolar partial pressures; and (e) display means connected to said analyzer means for displaying said relative change, whereby normal and abnormal ventilatory responses may be distinguished.
Claim 3
Dependent Claim
63 words
Apparatus as in claim 1 wherein said means for introducing known percentages of test gas in air being inspired comprises: (a) means for connecting said source of test gas to the patient's breathing orifices; (b) sample storage means for storing a plurality of gas samples of known constituent concentrations; and (c) means for selectively connecting said sample storage means to said connecting means.
Claim 4
Dependent Claim
62 words
Apparatus as in claim 2 wherein said means for measuring said inspiratory and expiratory flow of air comprises: (a) a pressure transducing head disposed in said connecting means for sensing differential pressure changes between two predetermined locations therein; and (b) means coupled to said transducing head for converting said differential pressure change into an analog electrical signal comprising said first electrical signals.
Claim 5
Dependent Claim
125 words
Apparatus as in claim 3 wherein said analyzer means comprises: (a) multiplexer means having a plurality of input channels adapted to receive at least said analog electrical signal and said second electrical signal; (b) analog-to-digital converter means coupled to said multiplexer means for individually receiving signals applied to said plurality of input channels; (c) said programmable computing means including storage means for holding a program of instructions and operands at addressable locations therein, control means, arithmetic means and input and output means, said input means being coupled to said analog-to-digital converter means for receiving operands therefrom and storing same in said storage means under direction of said control means; and (d) said display means being coupled to said output means of said programmable computing means.
Claim 6
Dependent Claim
25 words
Apparatus as in claim 1 wherein said analyzer means further includes means for detecting when inspiratory or expiratory flow patterns fail to meet predetermined criteria.
Claim 7
Dependent Claim
58 words
Apparatus as in claim 1 wherein said analyzer means further includes means for detecting intervals during which the integrated value of said first electrical signal one less than a predetermined threshold level; and means responsive to said detecting means for inhibiting said programmable computing means from producing computations based upon said first electrical signal existing during said intervals.
Claim 8
Independent Claim
174 words
A method for diagnosing possible brain stem disfunction relating to respiration in a patient comprising the steps of: (a) selectively introducing a plurality of known percentages of test gases into air being inspired by said patient; (b) measuring the inspiratory and expiratory flow of air to and from said patient during time periods related to introduction of each such gas percentage and for developing first electrical signals proportional thereto; (c) measuring the percentage concentration of carbon dioxide gas in the air expired by said patient during time periods related to introduction of each such gas percentage and for producing second electrical signals proportional thereto; (d) computing the integral of said first signals over respective predetermined time intervals; (e) computing from said second signals the respective alveolar partial pressure of carbon dioxide gas in the expiratory air flow from the lungs of said patient; (f) determining the change in said integrated first signals relative to said respective alveolar partial pressures; and (g) displaying said relative change, whereby normal and abnormal ventilatory responses may be distinguished.
Claim 9
Independent Claim
174 words
A method for diagnosing possible brain stem disfunction relating to respiration in a patient comprising the steps of: (a) selectively introducing a plurality of known percentages of test gases into air being inspired by said patient; (b) measuring the inspiratory and expiratory flow of air to and from said patient during time periods related to introduction of each such gas percentage and for developing first electrical signals proportional thereto; (c) measuring the percentage concentration of carbon dioxide gas in the air expired by said patient during time periods related to introduction of each such gas percentage and for producing second electrical signals proportional thereto; (d) computing the integral of said first signals over respective predetermined time intervals; (e) computing from said second signals the respective alveolar partial pressure of carbon dioxide gas in the expiratory air flow from the lungs of said patient; (f) determining the change in said integrated first signals relative to said respective alveolar partial pressures; and (g) displaying said relative change, whereby normal and abnormal ventilatory responses may be distinguished.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-04-03 | 1987-10-03 | 1988-04-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-04-03 | 1991-10-03 | 1992-04-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-04-03 | 1995-10-03 | 1996-04-03 | $7700.00 | Window Closed / Lapsed |