US4428924A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Preparation for diagnostic radiology
Assignee: Linton Medical Services Ltd
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Filing: 1980-04-14
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Granted: 1984-01-31
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Expires: 2000-04-14
Abstract
Abstract A method for making a preparation for diagnostic radiology. The method consists of agitating a radio opaque substance and a carrier in a vessel, controlling temperature and pressure, admitting gas to the vessel and withdrawing mixture from the vessel such that dissolved gas does not fall below a level at which gas is released within the patient when the preparation is ingested.
Inventors
- 👤 Arthur R. Millington
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 13:10
CPC Classifications
A; A61; A61K; A61K49/00; A61K49/04; A61K49/0404
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
178 words
A method of producing a preparation for diagnostic radiology, the preparation, when taken into the body of a user, releasing a gas that expands within the body of a user, comprising: placing a mixture containing a radio opaque substance and a carrier in a pressure vessel, the radio opaque substance being present in a quantity sufficient for diagnostic radiology; adding a non-toxic gas to the pressure vessel; agitating the mixture for a period of time sufficient to produce a substantially uniform suspension of radio opaque substance in the carrier and to obtain a predetermined level of dissolved gas within the mixture, the level being sufficient to cause release of the gas within the body of a user; controlling the temperature and pressure within the vessel so that the temperature is below ambient and the pressure is elevated; and withdrawing the preparation from the vessel for administration to a patient in such a way that the concentration of dissolved gas does not fall below a level at which gas is released within the patient when the preparation is ingested.
Claim 2
Independent Claim
178 words
A method of producing a preparation for diagnostic radiology, the preparation, when taken into the body of a user, releasing a gas that expands within the body of a user, comprising: placing a mixture containing a radio opaque substance and a carrier in a pressure vessel, the radio opaque substance being present in a quantity sufficient for diagnostic radiology; adding a non-toxic gas to the pressure vessel; agitating the mixture for a period of time sufficient to produce a substantially uniform suspension of radio opaque substance in the carrier and to obtain a predetermined level of dissolved gas within the mixture, the level being sufficient to cause release of the gas within the body of a user; controlling the temperature and pressure within the vessel so that the temperature is below ambient and the pressure is elevated; and withdrawing the preparation from the vessel for administration to a patient in such a way that the concentration of dissolved gas does not fall below a level at which gas is released within the patient when the preparation is ingested.
Claim 3
Dependent Claim
13 words
A method as claimed in claim 1, wherein the gas is carbon dioxide.
Claim 4
Dependent Claim
12 words
A method as claimed in claim 1, wherein the gas is nitrogen.
Claim 5
Dependent Claim
18 words
A method as claimed in claim 1, wherein the gas is a mixture of carbon dioxide and nitrogen.
Claim 6
Dependent Claim
15 words
A method as claimed in claim 1, wherein the radio opaque substance is barium sulphate.
Claim 7
Dependent Claim
13 words
A method as claimed in claim 1, wherein the preparation is continuously agitated.
Claim 8
Dependent Claim
12 words
A method as claimed in claim 1, wherein the agitation is mechanical.
References Cited (Backward Citations)
US2659690A
Cited
US3689630A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-01-30 | 1987-08-01 | 1988-01-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-01-30 | 1991-08-01 | 1992-01-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-01-30 | 1995-08-01 | 1996-01-31 | $7700.00 | Window Closed / Lapsed |