US4415491A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Synthetic vaccine peptide epitomes of hepatitis B surface antigen
Assignee: University of California, San Diego
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Filing: 1980-01-14
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Granted: 1983-11-15
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Expires: 2000-01-14
Abstract
Abstract Novel oligopeptides are provided having serologic activity for the a determinant of hepatitis B virus surface antigen. Included in the oligopeptide chain are a sequence of at least two cysteines and a lysine in proximity to the cysteines. The oligopeptides can find use in immunoassays, the formulation of vaccines, and the production of antisera.
Inventors
- 👤 Girish N. Vyas
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 19:16
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/005; C12; C12N; C12N2730/00; C12N2730/00011; C12N2730/10011; C12N2730/10111; C12N2730/10122; Y; Y10; Y10S; Y10S436/00; Y10S436/82; Y10S530/00; Y10S530/806; Y10S930/00; Y10S930/01; Y10S930/22; Y10S930/223
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
12 words
An oligopeptide of the formula H-TYR-PRO-SER-CYS-CYS-CYS-THR-LYS-PRO-THR-ASP-GLY-ASN-OH; or H-TYR-PRO-SER-CYS-CYS-CYS-THR-LYS-PRO-SER-ASP-GLY-ASN-OH; or H-PHE-PRO-SER-CYS-CYS-CYS-THR-LYS-PRO-THR-ASP-GLY-ASN-OH; or H-PHE-PRO-SER-CYS-CYS-CYS-THR-LYS-PRO-SER-ASP-GLY-ASN-OH.
Claim 2
Dependent Claim
12 words
An oligopeptide of the formula H-TYR-PRO-SER-CYS-CYS-CYS-THR-LYS-PRO-THR-ASP-GLY-ASN-OH; or H-TYR-PRO-SER-CYS-CYS-CYS-THR-LYS-PRO-SER-ASP-GLY-ASN-OH; or H-PHE-PRO-SER-CYS-CYS-CYS-THR-LYS-PRO-THR-ASP-GLY-ASN-OH; or H-PHE-PRO-SER-CYS-CYS-CYS-THR-LYS-PRO-SER-ASP-GLY-ASN-OH.
Claim 3
Dependent Claim
10 words
An oligopeptide according to claim 1 of the formula H-TYR-PRO-SER-CYS-CYS-CYS-THR-LYS-PRO-SER-ASP-GLY-ASN-OH.
Claim 4
Dependent Claim
10 words
An oligopeptide according to claim 1 of the formula H-PHE-PRO-SER-CYS-CYS-CYS-THR-LYS-PRO-THR-ASP-GLY-ASN-OH.
Claim 5
Dependent Claim
10 words
An oligopeptide according to claim 1 of the formula H-PHE-PRO-SER-CYS-CYS-CYS-THR-LYS-PRO-SER-ASP-GLY-ASN-OH.
Claim 6
Dependent Claim
12 words
An oligopeptide according to claim 1, bonded to an immunogenic carrier material.
Claim 7
Dependent Claim
10 words
An oligopeptide according to claim 1 labeled with a fluorescer.
Claim 8
Dependent Claim
10 words
An oligopeptide according to claim 1 labeled with an enzyme.
Claim 9
Dependent Claim
12 words
An oligopeptide according to claim 1 having a radionuclide bonded to carbon.
Claim 10
Dependent Claim
6 words
An oligopeptide of the formula H-TYR-PRO-SER-CYS-CYS-CYS-THR-LYS-PRO-THR-ASP-GLY-ASN-OH.
Claim 11
Dependent Claim
6 words
An oligopeptide of the formula H-TYR-PRO-SER-CYS-CYS-CYS-THR-LYS-PRO-THR-ASP-GLY-ASN-OH.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-11-14 | 1987-05-16 | 1987-11-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-11-14 | 1991-05-16 | 1991-11-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-11-14 | 1995-05-16 | 1995-11-15 | $7700.00 | Window Closed / Lapsed |