US4393048A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Protective gel composition for wounds
Assignee: United States Department of the Army
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Filing: 1981-10-30
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Granted: 1983-07-12
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Expires: 2001-10-30
Abstract
Abstract Water soluble hydrogels of alkali metal alginate and glycerine have been found to be excellent wound dressings. The gels dry to an adherent, non-toxic pliable protective film which can be removed by water-washing when desired. The gels are also compatible with medicaments and hence can serve as vehicles or carriers for medicament application to wounds as well as a protective cover.
Inventors
- 👤 Arthur D. Mason, Jr.
- 👤 Avery A. Johnson, Jr.
- 👤 Harrel L. Walker
- 👤 Eleanor G. Bowler
- 👤 Charles R. Ritchey
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:47
CPC Classifications
A; A61; A61L; A61L26/00; A61L26/0009; A61L26/0023; Y; Y10; Y10S; Y10S424/00; Y10S424/13
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
82 words
A gel composition, having use as a wound dressing, comprising a water-soluble hydrogel consisting essentially of about 0.5 to 3% by weight of alkali metal alginate, about 8 to 12% by weight glycerine and about 82 to 90% by weight water wherein said hydrogel has a pH in the range of 6.8 to 7.2 and which upon drying forms a flexible, stretchable, transparent water-soluble protective film, nontoxic and adherent to a wound surface to which said gel composition is applied for protection.
Claim 2
Dependent Claim
82 words
A gel composition, having use as a wound dressing, comprising a water-soluble hydrogel consisting essentially of about 0.5 to 3% by weight of alkali metal alginate, about 8 to 12% by weight glycerine and about 82 to 90% by weight water wherein said hydrogel has a pH in the range of 6.8 to 7.2 and which upon drying forms a flexible, stretchable, transparent water-soluble protective film, nontoxic and adherent to a wound surface to which said gel composition is applied for protection.
Claim 3
Dependent Claim
15 words
A gel composition according to claim 1 wherein the alkali metal alginate is sodium alginate.
Claim 4
Dependent Claim
22 words
A gel composition according to claim 1 further comprising a medicament dispersed therein in an amount therapeutically effective as a wound dressing.
Claim 5
Dependent Claim
13 words
A gel composition according to claim 3 wherein the medicament is silver nitrate.
Claim 6
Dependent Claim
14 words
A gel composition according to claim 3 wherein the medicament is a sulfa drug.
Claim 7
Dependent Claim
13 words
A gel composition according to claim 3 wherein the medicament is an antibiotic.
Claim 8
Dependent Claim
14 words
A gel composition according to claim 3 wherein the medicament is a chemotherapeutic agent.
Claim 9
Dependent Claim
29 words
A gel composition according to claim 3 wherein the amount of medicament is in the range of from about 0.01% to about 10% by weight of the gel composition.
Claim 10
Dependent Claim
13 words
A gel composition according to claim 5 wherein the medicament is mafenide acetate.
Claim 11
Independent Claim
83 words
A method for protecting wounds which comprises applying over a wound surface a coating of a gel composition comprising a water-soluble hydrogel consisting essentially of about 0.5 to 3% by weight alkali metal alginate, about 8 to 12% by weight glycerine and about 82 to 90% by weight water wherein said hydrogel has a pH in the range of 6.8 to 7.2 and allowing the coating to dry to a water-soluble, flexible, stretchable, transparent, protective film, non-toxic and adherent to said wound surface.
Claim 12
Independent Claim
83 words
A method for protecting wounds which comprises applying over a wound surface a coating of a gel composition comprising a water-soluble hydrogel consisting essentially of about 0.5 to 3% by weight alkali metal alginate, about 8 to 12% by weight glycerine and about 82 to 90% by weight water wherein said hydrogel has a pH in the range of 6.8 to 7.2 and allowing the coating to dry to a water-soluble, flexible, stretchable, transparent, protective film, non-toxic and adherent to said wound surface.
Claim 13
Dependent Claim
14 words
A method according to claim 10 wherein the alkali metal alginate is sodium alginate.
Claim 14
Dependent Claim
22 words
A method according to claim 10 wherein the gel composition comprises a medicament in an amount therapeutically effective as a wound dressing.
Claim 15
Dependent Claim
13 words
A method according to claim 10 wherein the wound is a burn wound.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-07-11 | 1987-01-10 | 1987-07-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-07-11 | 1991-01-10 | 1991-07-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-07-11 | 1995-01-10 | 1995-07-12 | $7700.00 | Window Closed / Lapsed |