US4374932A
Expired / Lapsed
US
⏱️ 0.0 years remaining
5-ASA Drug delivery system
Assignee: Pfizer Health AB
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Filing: 1981-06-08
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Granted: 1983-02-22
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Expires: 2001-06-08
Abstract
Abstract The present invention relates to novel compounds for the prophylaxis and treatment of Inflammatory Bowel disease (IBD) via the administration of an effective amount in a suitable pharmaceutical dosage of a polymeric agent for releasing 5,5'-azobis-salicylic acid which comprises a non-degradable anionic exchange resin and the dianionic form of 5,5'-azobis-salicylic acid. The 5,5'-azobis-salicylic acid undergoes bacterial cleavage in the mammalian lower bowel to release 5-aminosalicylic acid.
Inventors
- 👤 Barnett S. Pitzele
- 👤 Peter H. Jones
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 19:11
CPC Classifications
C; C07; C07C; C07C245/00; C07C245/02; C07C245/06; C07C245/08; A; A61; A61K; A61K47/00; A61K47/50; A61K47/51; A61K47/56; A61K47/58; A61K47/585; A61P; A61P1/00; A61P1/04
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
22 words
A polymeric anionic exchange complex comprising a pharmacologically acceptable, non-absorbable, non-degradable anionic exchange resin and the dianionic form of 5,5'-azobis salicylic acid.
Claim 2
Dependent Claim
22 words
A polymeric anionic exchange complex comprising a pharmacologically acceptable, non-absorbable, non-degradable anionic exchange resin and the dianionic form of 5,5'-azobis salicylic acid.
Claim 3
Dependent Claim
29 words
A complex according to claim 1 wherein the resin is a polystyrene polymer cross-linked with 2% divinylbenzene and functionalized on the benzene ring with a trialkyl ammonium methyl group.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-02-21 | 1986-08-23 | 1987-02-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-02-21 | 1990-08-23 | 1991-02-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-02-21 | 1994-08-23 | 1995-02-22 | $7700.00 | Window Closed / Lapsed |