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US4332795A Expired / Lapsed US ⏱️ 0.0 years remaining

Inflammation-preventing pharmaceutical composition of oral administration

Assignee: A Natterman und Cie GmbH
•
Filing: 1979-12-17
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Granted: 1982-06-01
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Expires: 1999-12-17
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Abstract

Abstract A novel pharmaceutical composition is provided which is suitable for the prevention of inflammation and which comprises non-steroidal inflammation-preventing compound (e.g. pyrazolones, salicylic acid derivatives, indoles, indanes, and phenylacetic acid and anthranilic acid derivatives) and at least one phospholipid.

Inventors

  • 👤 Miklos Ghyczy
  • 👤 Adorjan Erdos
  • 👤 Gunter Heidemann
  • 👤 Gotz Ritzmann

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 09:49
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/66; A61K31/683; A61K31/685; A61K47/00; A61K47/06; A61K47/24; A61K9/00; A61K9/20; A61K9/2004; A61K9/2013; A61K9/48; A61K9/4841; A61K9/4858; A61P; A61P29/00

Claims Analysis

Total Claims: 16
Claim 1
Independent Claim 42 words
A method of alleviating inflammation in a mammal comprising orally administering to said mammal an effective inflammation-alleviating amount of a pharmaceutical composition comprising a phospholipid and a non-steroidal inflammation-preventing indole in a molar ratio ranging from about 0.1:1 to about 20:1, respectively.
Claim 2
Independent Claim 42 words
A method of alleviating inflammation in a mammal comprising orally administering to said mammal an effective inflammation-alleviating amount of a pharmaceutical composition comprising a phospholipid and a non-steroidal inflammation-preventing indole in a molar ratio ranging from about 0.1:1 to about 20:1, respectively.
Claim 3
Dependent Claim 19 words
The method of claim 1 wherein said indole is selected from the group consisting of indometacine, glucametacine, and acemetacine.
Claim 4
Dependent Claim 10 words
The method of claim 2 wherein said indole is indometacine.
Claim 5
Dependent Claim 10 words
The method of claim 2 wherein said indole is acemetacine.
Claim 6
Dependent Claim 23 words
The method of claim 1 wherein said phospholipid and said indole are present in molar ratios ranging from about 0.5:1 to about 2:1.
Claim 7
Dependent Claim 10 words
The method of claim 1 wherein said phospholipid is phosphatidylcholine.
Claim 8
Dependent Claim 10 words
The method of claim 1 wherein said phospholipid is phosphatidylinositol.
Claim 9
Dependent Claim 41 words
A pharmaceutical composition in a form for oral administration in the prevention of inflammation in mammals comprising an effective inflammation-alleviating amount of a phospholipid and a non-steroidal inflammation-preventing indole in a molar ratio ranging from about 0.1:1 to about 20:1, respectively.
Claim 10
Dependent Claim 41 words
A pharmaceutical composition in a form for oral administration in the prevention of inflammation in mammals comprising an effective inflammation-alleviating amount of a phospholipid and a non-steroidal inflammation-preventing indole in a molar ratio ranging from about 0.1:1 to about 20:1, respectively.
Claim 11
Dependent Claim 20 words
The pharmaceutical composition of claim 8, wherein said indole is selected from the group consisting of indometacine, glucametacine, and acemetacine.
Claim 12
Dependent Claim 11 words
The pharmaceutical composition of claim 9 wherein said indole is indometacine.
Claim 13
Dependent Claim 11 words
The pharmaceutical composition of claim 9 wherein said indole is acemetacine.
Claim 14
Dependent Claim 24 words
The pharmaceutical composition of claim 8 wherein said phospholipid and said indole are present in molar ratios ranging from about 0.5:1 to about 2:1.
Claim 15
Dependent Claim 11 words
The pharmaceutical composition of claim 8 wherein said phospholipid is phosphatidylchloine.
Claim 16
Dependent Claim 11 words
The pharmaceutical composition of claim 8 wherein said phospholipid is phosphatidylinositol.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1985-05-31 1985-11-30 1986-06-01 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1989-05-31 1989-11-30 1990-06-01 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1993-05-31 1993-11-30 1994-06-01 $7700.00 Window Closed / Lapsed

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