US4309408A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Effervescent powders
Assignee: Beecham Group PLC
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Filing: 1979-11-09
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Granted: 1982-01-05
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Expires: 1999-11-09
Abstract
Abstract Effervescent analgesic powders which comprise paracetamol D.C., and metoclopramide or an acid addition salt thereof, the weight ratio of paracetamol D.C. to metoclopramide or the acid addition salt thereof lying in the range 50:1 to 250:1, and a process for their preparation.
Inventors
- 👤 Ram D. Pathak
- 👤 Elizabeth J. Treherne
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:55
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/16; A61K31/165; A61K9/00; A61K9/0002; A61K9/0007; A61P; A61P25/00; A61P25/04
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
25 words
An analgesic effervescent powder comprising paracetamol D.C. and metoclopramide or an acid addition salt thereof in a weight ratio of from 80:1 to 120:1 respectively.
Claim 2
Dependent Claim
25 words
An analgesic effervescent powder comprising paracetamol D.C. and metoclopramide or an acid addition salt thereof in a weight ratio of from 80:1 to 120:1 respectively.
Claim 3
Dependent Claim
23 words
A powder according to claim 1 wherein the metoclopramide or its acid addition salt is present at 0.05 to 0.4 percent by weight.
Claim 4
Dependent Claim
19 words
A powder according to claim 1 containing (a) sodium bicarbonate and (b) sodium dihydrogen citrate or disodium hydrogen citrate.
Claim 5
Dependent Claim
31 words
A unit of the powder according to claim 1 containing from 0.4 to 0.6 g of paracetamol D.C. and 4 to 6 mg of metoclopramide or an acid addition salt thereof.
Claim 6
Dependent Claim
45 words
A method of treating migraine headache, which method comprises administering to the sufferer a therapeutically effective amount of paracetamol D.C. and metoclopramide or an acid addition salt thereof in the aqueous solution derived from the reaction of a powder according to claim 1 and water.
References Cited (Backward Citations)
US3136669A
Cited
FR2013552A1
Cited
FR2085730B1
Cited
BE769156A
Cited
FR2187312B1
Cited
GB1442159A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-01-04 | 1985-07-06 | 1986-01-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-01-04 | 1989-07-06 | 1990-01-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-01-04 | 1993-07-06 | 1994-01-05 | $7700.00 | Window Closed / Lapsed |