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US4301800A Expired / Lapsed US ⏱️ 0.0 years remaining

Blood bags having an insert member

Assignee: Baxter International Inc
•
Filing: 1980-05-19
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Granted: 1981-11-24
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Expires: 2000-05-19
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Abstract

Abstract A blood bag or other container which is made of a flexible, hemocompatible, sterilizable plastic material free of blood-extractable plasticizer. The blood bag contains an insert member which comprises a non-toxic, sterilizable plastic formulation which contains from 5 to 70 percent by weight of a blood-extractable plasticizer selected from the group consisting of the dioctylphthalates and dioctyladipates. Such a blood bag is capable of reducing the plasma hemoglobin in stored blood, when compared with similar blood bags without the insert member.

Inventors

  • 👤 Henry W. Collins

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 12:02
CPC Classifications
A; A61; A61J; A61J1/00; A61J1/05; A61J1/10; A61M; A61M1/00; A61M1/36; A61M1/3687; C; C08; C08K; C08K5/00; C08K5/04; C08K5/10; C08K5/12; Y; Y10; Y10S; Y10S128/00; Y10S128/24

Claims Analysis

Total Claims: 24
Claim 1
Independent Claim 71 words
A blood bag which comprises a flexible, translucent container equipped with access tubing and sealed access ports, said blood bag comprising: a flexible, hemocompatible, sterilizable plastic material, essentially free of blood-extractable plasticizer, said blood bag containing an insert member, said insert member comprising a non-toxic, sterilizable plastic formulation which contains from 5 to 70 percent by weight of a blood-extractable plasticizer selected from the group consisting of the dioctylphthalates and dioctyladipates.
Claim 2
Dependent Claim 71 words
A blood bag which comprises a flexible, translucent container equipped with access tubing and sealed access ports, said blood bag comprising: a flexible, hemocompatible, sterilizable plastic material, essentially free of blood-extractable plasticizer, said blood bag containing an insert member, said insert member comprising a non-toxic, sterilizable plastic formulation which contains from 5 to 70 percent by weight of a blood-extractable plasticizer selected from the group consisting of the dioctylphthalates and dioctyladipates.
Claim 3
Dependent Claim 12 words
The blood bag of claim 1 in which said plasticizer is dioctylphthalate.
Claim 4
Dependent Claim 12 words
The blood bag of claim 1 in which said plasticizer is di-2-ethylhexylphthalate.
Claim 5
Dependent Claim 12 words
The blood bag of claim 1 in which said plasticizer is di-2-ethylhexyladipate.
Claim 6
Dependent Claim 22 words
The blood bag of claim 1 in which said insert member is from 15 to 50 percent by weight of said plasticizer.
Claim 7
Dependent Claim 15 words
The blood bag of claim 5 in which said insert member is a plastic sheet.
Claim 8
Dependent Claim 18 words
The blood bag of claim 5 in which said insert member comprises a blood-compatible plasticized polyvinyl chloride formulation.
Claim 9
Dependent Claim 75 words
A blood container which comprises a hemo-compatible, sterilizable material, essentially free of blood-extractable plasticizer, said blood container containing an insert member, said insert member comprising a non-toxic, sterilizable plastic formulation which contains sufficient material selected from the group consisting of dioctylphthalates and dioctyladipates to cause blood stored in said blood bag for 21 days to exhibit a reduced plasma hemoglobin content when compared with blood stored in a comparable blood container free of said material.
Claim 10
Dependent Claim 75 words
A blood container which comprises a hemo-compatible, sterilizable material, essentially free of blood-extractable plasticizer, said blood container containing an insert member, said insert member comprising a non-toxic, sterilizable plastic formulation which contains sufficient material selected from the group consisting of dioctylphthalates and dioctyladipates to cause blood stored in said blood bag for 21 days to exhibit a reduced plasma hemoglobin content when compared with blood stored in a comparable blood container free of said material.
Claim 11
Dependent Claim 12 words
The blood container of claim 8 in which said plasticizer is dioctylphthalate.
Claim 12
Dependent Claim 12 words
The blood container of claim 9 in which said plasticizer is di-2-ethylhexylphthalate.
Claim 13
Dependent Claim 75 words
A blood container which comprises a hemo-compatible, sterilizable material, essentially free of blood-extractable plasticizer, said blood container containing an insert member, said insert member comprising a non-toxic, sterilizable, plastic formulation which contains sufficient antihemolytic agent, capable of leaching from said plastic formulation, to cause blood stored in said blood bag for 21 days to exhibit a reduced plasma hemoglobin content when compared with blood stored in a comparable blood container free of said antihemolytic agent.
Claim 14
Dependent Claim 75 words
A blood container which comprises a hemo-compatible, sterilizable material, essentially free of blood-extractable plasticizer, said blood container containing an insert member, said insert member comprising a non-toxic, sterilizable, plastic formulation which contains sufficient antihemolytic agent, capable of leaching from said plastic formulation, to cause blood stored in said blood bag for 21 days to exhibit a reduced plasma hemoglobin content when compared with blood stored in a comparable blood container free of said antihemolytic agent.
Claim 15
Independent Claim 85 words
The method of storing blood which comprises placing said blood for a period of days into a flexible, hemocompatible, sterilizable plastic material, essentially free of blood-extractable plasticizer, said blood bag containing an insert member, said insert member comprising a non-toxic, sterilizable, plastic formulation which contains a blood extractable antihemolytic agent in sufficient quantity to cause blood stored in said blood bag for 21 days to exhibit a reduced plasma hemoglobin content when compared with blood stored in a comparable blood container free of said material.
Claim 16
Independent Claim 85 words
The method of storing blood which comprises placing said blood for a period of days into a flexible, hemocompatible, sterilizable plastic material, essentially free of blood-extractable plasticizer, said blood bag containing an insert member, said insert member comprising a non-toxic, sterilizable, plastic formulation which contains a blood extractable antihemolytic agent in sufficient quantity to cause blood stored in said blood bag for 21 days to exhibit a reduced plasma hemoglobin content when compared with blood stored in a comparable blood container free of said material.
Claim 17
Independent Claim 70 words
The method of storing blood which comprises placing blood for a period of days in a blood bag made of a flexible, hemocompatible, sterilizable plastic material, essentially free of blood-extractable plasticizer, said blood bag containing an insert member, said insert member comprising a non-toxic, sterilizable plastic formulation which contains from five to 70 percent by weight of an antihemolytic material selected from the group consisting of the dioctylphthalates and dioctyladipates.
Claim 18
Independent Claim 70 words
The method of storing blood which comprises placing blood for a period of days in a blood bag made of a flexible, hemocompatible, sterilizable plastic material, essentially free of blood-extractable plasticizer, said blood bag containing an insert member, said insert member comprising a non-toxic, sterilizable plastic formulation which contains from five to 70 percent by weight of an antihemolytic material selected from the group consisting of the dioctylphthalates and dioctyladipates.
Claim 19
Dependent Claim 16 words
The method of claim 13 in which the material contained in said insert member is dioctylphthalate.
Claim 20
Dependent Claim 16 words
The method of claim 14 in which the material contained in said insert member is di-2-ethylhexylphthalate.
Claim 21
Dependent Claim 16 words
The method of claim 13 in which the material container in said insert member is di-2-ethylhexyladipate.
Claim 22
Dependent Claim 22 words
The method of claim 13 in which said insert member is from 15 to 50 percent by weight of said antihemolytic material.
Claim 23
Dependent Claim 14 words
The method of claim 13 in which said insert member is a plastic sheet.
Claim 24
Dependent Claim 17 words
The method of claim 13 in which said insert member comprises a blood-compatible, plasticized polyvinyl chloride formulation.

References Cited (Backward Citations)

US3064647A Cited
US3279996A Cited
US3186961A Cited
US3710795A Cited
US3940802A Cited
US3977404A Cited
US4082509A Cited
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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1984-11-23 1985-05-25 1985-11-24 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1988-11-23 1989-05-25 1989-11-24 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1992-11-23 1993-05-25 1993-11-24 $7700.00 Window Closed / Lapsed

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