Patent US5395456A successfully refreshed from Google Patents.
US4285464A
Expired / Lapsed
US
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Apparatus for separation of blood into components thereof
Assignee: Haemonetics Corp
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Filing: 1980-06-02
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Granted: 1981-08-25
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Expires: 2000-06-02
Abstract
Abstract Apparatus is disclosed for centrifugally separating blood into a first blood component, such as a plasma-rich component, and a second blood component, such as a plasma-poor component. This apparatus employs a self-balancing centrifuge intended to be used immediately adjacent to a blood donor. The blood pathway is completely disposable and includes a phlebotomy needle and blood compatible tubing connecting the phlebotomy needle to a flexible blood processing bag designed to be supported within a contoured processing chamber in the centrifuge rotor so that second blood component travels along a short internal bag dimension to achieve separation. A displacement chamber having a fluid operated diaphram is also positioned within the blood processing chamber of the centrifuge rotor. Separated first blood component can be expressed from the flexible blood bag by movement of the diaphram and collected in a receiver container as the centrifuge rotor spins. The centrifuge rotor can then be stopped to allow return of second blood component to the donor.
Inventors
- 👤 Allen Latham, Jr.
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 16:18
CPC Classifications
B; B04; B04B; B04B5/00; B04B5/04; B04B5/0407; B04B5/0428; A; A61; A61M; A61M1/00; A61M1/02; A61M1/0209; A61M1/34; A61M1/3496; A61M1/36; A61M1/3693; A61M1/3698; A61M2205/00; A61M2205/33; A61M2205/3379; A61M2205/3393; A61M5/00; A61M5/14; A61M5/142; A61M5/145; A61M5/148; A61M5/1483; B04B9/00; B04B9/14; B04B2009/143
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
219 words
A disposable blood pathway for use in the centrifugal separation of blood in a spinning centrifuge rotor into a first blood component and a second blood component comprising, in combination: a flexible blood processing bag having at least one inlet port and one outlet port, said flexible blood processing bag having inner and outer wall members with a relatively small distance between said inner and said outer wall members compared to other internal bag dimensions so that the distance blood components travel during centrifugal separation is minimized when said bag is supported in the centrifuge rotor in a position whereby said relatively small distance is positioned transverse to the axis of rotation so that second blood component travels along this short internal bag dimension during centrifugal separation; a receiver container for receiving first blood component separated in said flexible blood processing bag, said receiver container having at least one inlet port and having a geometry which minimizes imbalance in said centrifuge rotor as separated first blood component is introduced into the receiver container; blood-compatible tubing connecting an outlet port of said flexible blood processing bag with an inlet port of said receiver container; and blood compatible tubing for providing fluid communication between a source of blood to be separated and an inlet port on said flexible blood processing bag.
Claim 2
Dependent Claim
219 words
A disposable blood pathway for use in the centrifugal separation of blood in a spinning centrifuge rotor into a first blood component and a second blood component comprising, in combination: a flexible blood processing bag having at least one inlet port and one outlet port, said flexible blood processing bag having inner and outer wall members with a relatively small distance between said inner and said outer wall members compared to other internal bag dimensions so that the distance blood components travel during centrifugal separation is minimized when said bag is supported in the centrifuge rotor in a position whereby said relatively small distance is positioned transverse to the axis of rotation so that second blood component travels along this short internal bag dimension during centrifugal separation; a receiver container for receiving first blood component separated in said flexible blood processing bag, said receiver container having at least one inlet port and having a geometry which minimizes imbalance in said centrifuge rotor as separated first blood component is introduced into the receiver container; blood-compatible tubing connecting an outlet port of said flexible blood processing bag with an inlet port of said receiver container; and blood compatible tubing for providing fluid communication between a source of blood to be separated and an inlet port on said flexible blood processing bag.
Claim 3
Dependent Claim
29 words
A disposable blood pathway of claim 1 wherein said blood processing bag has an outlet for separated first component located at approximately the center of its inner wall member.
Claim 4
Dependent Claim
39 words
A disposable blood pathway of claim 2 wherein said blood processing bag has an inlet for blood to be separated at the top thereof and at least one port for removal of said second blood component therefrom after separation.
Claim 5
Dependent Claim
67 words
A disposable blood pathway of claim 3 wherein said blood processing bag has two sealed spike ports for reconnection and said blood compatible tubing providing fluid communication between said source of blood and the inlet port of said disposable blood processing bag is dielectrically sealable and additionally contains two sealed insert spikes adapted for insertion into the two sealed spike ports of said disposable blood processing bag.
Claim 6
Dependent Claim
48 words
A disposable blood pathway of claims 1 or 4 wherein said receiver container has the form of a volume of revolution with the upper end larger than its lower end and a inlet port for first blood component at a point of substantially maximum diameter of said container.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-08-24 | 1985-02-23 | 1985-08-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-08-24 | 1989-02-23 | 1989-08-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-08-24 | 1993-02-23 | 1993-08-25 | $7700.00 | Window Closed / Lapsed |