US4277367A
Expired / Lapsed
US
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Phantom material and method
Assignee: Wisconsin Alumni Research Foundation
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Filing: 1978-10-23
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Granted: 1981-07-07
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Expires: 1998-10-23
Abstract
Abstract Tissue mimicking material for use in ultrasound phantoms formulated as a uniform suspension of solid particles of graphite, talc, pumice, polyethylene microspheres, or liquid particles of vegetable oils, kerosine, or combinations thereof described as scatterers in a congealed gelatin-water-alcohol-preservative matrix; containing detergents to create the liquid particles.
Inventors
- 👤 Ernest L. Madsen
- 👤 James A. Zagzebski
- 👤 Richard A. Banjavic
- 👤 Michele M. Burlew
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:57
CPC Classifications
G; G10; G10K; G10K11/00; G10K11/02; G01; G01N; G01N29/00; G01N29/22; G01N29/30; G09; G09B; G09B23/00; G09B23/28; G09B23/286; A; A61; A61B; A61B17/00; A61B2017/00681; A61B2017/00707; A61B2017/00716; Y; Y10; Y10T; Y10T436/00; Y10T436/10
Claims Analysis
Total Claims: 29
Claim 1
Independent Claim
57 words
Tissue mimicking material comprised of a scatterer in finely divided form uniformly dispersed throughout a congealed gel matrix, having in the absence of particulate scatterers a speed of sound within the range of 1400-1650 m/s, and formed of a gel forming material, water and an organic hydroxy compound soluble in the water, with or without a preservative.
Claim 2
Dependent Claim
57 words
Tissue mimicking material comprised of a scatterer in finely divided form uniformly dispersed throughout a congealed gel matrix, having in the absence of particulate scatterers a speed of sound within the range of 1400-1650 m/s, and formed of a gel forming material, water and an organic hydroxy compound soluble in the water, with or without a preservative.
Claim 3
Dependent Claim
16 words
Tissue mimicking material as claimed in claim 1 in which the gel forming material is gelatin.
Claim 4
Dependent Claim
16 words
Tissue mimicking material as claimed in claim 2 in which the gelatin is animal hide gelatin.
Claim 5
Dependent Claim
29 words
Tissue mimicking material as claimed in claim 1 in which the hydroxy compound is alcohol present in an amount within the range of 5-25% by volume of the gel.
Claim 6
Dependent Claim
14 words
Tissue mimicking material as claimed in claim 4 in which the alcohol is n-propanol.
Claim 7
Dependent Claim
16 words
Tissue mimicking material as claimed in claim 1 in which the scatterer is a graphite powder.
Claim 8
Dependent Claim
14 words
Tissue mimicking material as claimed in claim 1 in which the scatterer is talc.
Claim 9
Dependent Claim
15 words
Tissue mimicking material as claimed in claim 1 in which the scatterer is polyethylene microspheres.
Claim 10
Dependent Claim
27 words
Tissue mimicking material as claimed in claim 1 in which a preservative is present in an amount within the range of 0.01-1% by weight of the gel.
Claim 11
Dependent Claim
29 words
Tissue mimicking material as claimed in claim 1 in which the scatterer is graphite present in the gel in an amount within the range of 0.01-0.2 gm/cm 3 .
Claim 12
Dependent Claim
58 words
The method of preparing tissue mimicking material as claimed in claim 1 comprising mixing the gel forming material with a solution of the alcohol and water and preservative, heating the mixture to clarify, dispersing the scatterer into the clear solution and then congealing the mixture with rotation to maintain the scatterers in uniform distribution in the congealed product.
Claim 13
Dependent Claim
50 words
Tissue mimicking material comprising an oil and gelatin mixture, a solution of water and an alcohol soluble in the water and a preservative, with a detergent present in an amount to form a stable oil in water emulsion upon vigorous agitation of the mixture which congeals into a stable gel.
Claim 14
Dependent Claim
50 words
Tissue mimicking material comprising an oil and gelatin mixture, a solution of water and an alcohol soluble in the water and a preservative, with a detergent present in an amount to form a stable oil in water emulsion upon vigorous agitation of the mixture which congeals into a stable gel.
Claim 15
Dependent Claim
32 words
Tissue mimicking material as claimed in claim 12 in which the oil is present in the ratio of 0.1-0.6 parts by volume of oil to 1 part by volume of the gelatin.
Claim 16
Dependent Claim
15 words
Tissue mimicking material as claimed in claim 13 in which the oil is olive oil.
Claim 17
Dependent Claim
25 words
Tissue mimicking material as claimed in claim 12 in which the alcohol is n-propanol present in the ratio of 5-25% by volume of the gel.
Claim 18
Dependent Claim
27 words
Tissue mimicking material as claimed in claim 12 in which the detergent is present in an amount within the range of 0.2-10% by volume of the mixture.
Claim 19
Dependent Claim
14 words
Tissue mimicking material as claimed in claim 1 in which the scatterer is pumice.
Claim 20
Dependent Claim
16 words
Tissue mimicking material as claimed in claim 1 in which the gel-forming material is a polysaccharide.
Claim 21
Dependent Claim
15 words
Tissue mimicking material as claimed in claim 18 in which the gel-forming material is agar-agar.
Claim 22
Dependent Claim
16 words
Tissue mimicking material as claimed in claim 12 in which the oil is replaced by kerosine.
Claim 23
Dependent Claim
30 words
Tissue mimicking material as claimed in claim 20 in which the kerosine is present up to 0.33 parts by volume of kerosine to 1 part by volume of the gelatin.
Claim 24
Dependent Claim
21 words
Tissue mimicking material as claimed in claim 12 in which the oil is replaced by a solution of kerosine and oil.
Claim 25
Dependent Claim
27 words
Tissue mimicking material as claimed in claim 22 in which the ratio of volume of oil to volume of kerosine extends over the range O to infinity.
Claim 26
Dependent Claim
40 words
Tissue mimicking material as claimed in claim 22 in which the oil and kerosine is present in the ratio of 0.25 parts of volume of oil and 0.25 parts by volume kerosine to 1 part by volume of the gelatin.
Claim 27
Dependent Claim
108 words
Tissue mimicking material comprised of a scatterer in finely divided form uniformly dispersed throughout a congealed gel matrix, having in the absence of particulate scatterers a speed of sound within the range of 1400-1650 m/s, and formed of a gel forming material, water and an organic hydroxy compound soluble in the water, with or without a preservative, in which the gel forming material is gelatin, in which the hydroxy compound is n-propanol present in an amount within the range of 5-25% by volume of the gel, and in which the scatterer is graphite present in the gel in an amount within the range of 0.01-0.2 gm/cm 3 .
Claim 28
Dependent Claim
108 words
Tissue mimicking material comprised of a scatterer in finely divided form uniformly dispersed throughout a congealed gel matrix, having in the absence of particulate scatterers a speed of sound within the range of 1400-1650 m/s, and formed of a gel forming material, water and an organic hydroxy compound soluble in the water, with or without a preservative, in which the gel forming material is gelatin, in which the hydroxy compound is n-propanol present in an amount within the range of 5-25% by volume of the gel, and in which the scatterer is graphite present in the gel in an amount within the range of 0.01-0.2 gm/cm 3 .
Claim 29
Dependent Claim
27 words
A tissue mimicking material as claimed in claim 25 which includes a preservative present in an amount within the range of 0.01-1% by weight of the gel.
References Cited (Backward Citations)
US4002221A
Cited
US4116040A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-07-06 | 1985-01-05 | 1985-07-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-07-06 | 1989-01-05 | 1989-07-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-07-06 | 1993-01-05 | 1993-07-07 | $7700.00 | Window Closed / Lapsed |